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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461373 / VAT: CZ60461373
Czech Post certified digital mail code: sp4j9ch
Copyright: UCT Prague 2015
Information provided by the Department of International Relations and the Department of R&D. Technical support by the Computing Centre.
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[obsah] => DEPARTMENT OF FOOD ANALYSIS AND NUTRITION is a part of the Faculty of Food and Biochemical Technology. The research projects are mainly focused on food and feed quality, authenticity & safety related issues; investigations concerned with the impact of environmental conditions on the human food chain are also included. Special attention is paid to studies concerned with food components interactions / breakdown which may result in changes of nutritional value and/or sensory properties. In the recent years, interdisciplinary ‘omics’-based research aimed at the assessment of in vivo / in vitro effects induced by biologically active compounds, both beneficial and toxic, has been initiated.
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Our Department contributes to teaching of following Study Programmes:
Bachelor Study Programme
Chemistry and Technology, specialization Food Chemistry and Technology
Our teachers participate in learning of following subjects of this programme:
2nd year
Sensory Analysis (SIS or EMIL)
3rd year
Analysis of Food and Natural Products: Laboratory (SIS or EMIL)
Human Nutrition and Nutritional Policy (SIS or EMIL)
Food and Natural Products Analysis (SIS or EMIL)
Master Study Programmes
Biotechnology and Food Science
Our teachers participate in learning of following subjects of this programme:
1st year
Reaction Mechanisms in Food Chemistry (SIS or EMIL)
Special Food Analysis (SIS or EMIL)
Chemical Food Safety (SIS or EMIL)
Analysis of Bioactive Compounds (SIS or EMIL)
Control of Food Raw Materials and Commodities: Laboratory (SIS or EMIL)
2nd year
Isolation and Separation Methods (SIS or EMIL)
Doctoral Study Programme
Food and Natural Products
List of available PhD topics here
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[obsah] => Expert services and/or collaboration within common research projects are offered in the following areas:
A. FOOD/FEED CHEMICAL SAFETY, HUMAN EXPOSURE, AND FORENSIC ISSUES
Development of advanced methods for analysis of multiple contaminants and their metabolites in food, feed, biological and environmental matrices; investigation of preventive measures and mitigation strategies:
- Mycotoxins and natural plant toxins
- Pesticide / veterinary drugs residues
- POPs and other industrial contaminants
- Packaging contaminants / migrants
- Processing contaminants, antinutritive substances
- Nanoparticles
- ´Emerging´ contaminants
B. FOOD QUALITY ATTRIBUTES AND AUTHENTICATION; BIOPROSPECTION
Implementation of novel approaches for characterization and classification of:
- Metabolome / foodome: fingerprinting and/or profiling methods employing high resolution MS (ambient, LC, GC); advanced data processing; specific markers´ identification
- Biologically active compounds: non-target screening for ‘unknowns’ in plants / microorganisms; identification based on cutting-edge mass spectrometric techniques; assessment of chemical cocktails in combination with bioactivity testing
- Flavours / odours: combination of instrumental and sensory analysis; assessment based on the combination of comprehensive GC and olfactometry
TRAINING AND STUDY STAYS are offered to PhD students / postdoc young researchers interested in the above areas.
The UCT Prague closely cooperates with EU Reference Laboratories (EURLs) network in the field of QA/QC strategies, interlaboratory validation studies, reference materials and traceability of chemical measurements.
‘ACCREDITED TESTING AND METROLOGICAL LABORATORY’ of the Department of Food Analysis and Nutrition performs according to the International standard ISO/IEC 17025:2005; accreditation was provided by the Czech Accreditation Institute, signatory of the ILAC-MRA. For an external QC, the laboratory regularly participates in the proficiency testing (FAPAS, EU PT, IRMM, IAEA, etc.).
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[obsah] => Bioactive secondary metabolites of plants and microorganisms
Natural toxic compounds, mycotoxins, alkaloids
Some plants or microorganisms have the ability to synthesize complex organic compounds, products of specific secondary metabolism, generally used to protect producers from the harmful effects of the environment (predators or parasites). However, these substances are also usually toxic to humans, and can pose a significant health risk to consumers. Our working group deals mainly with mycotoxins, toxic secondary metabolites of filamentous micromycetes, and natural alkaloids, toxic products of some of the higher plants and some microscopic fungi. We work not only on the development of sensitive analytical methods based on chromatography and mass spectrometry, which are able to detect dozens of substances within a single analysis, but we also participate in the evaluation and interpretation of risks arising from the presence of these substances in food and natural products.
Publications
- Dzuman Z., Jonatova P., Stranska-Zachariasova M., Prusova N., Brabenec O., Novakova A., Fenclova M., Hajslova J.: Development of a new LC‒MS method for accurate and sensitive determination of 33 pyrrolizidine and 21 tropane alkaloids in plant-based food matrices. Analytical and Bioanalytical Chemistry (2020). Accepted. (doi: 10.1007/s00216-020-02848-6)
- Fenclova M., Novakova A., Viktorova J., Jonatova P., Dzuman Z., Ruml T., Kren V., Hajslova J., Vitek L., Stranska-Zachariasova M.: Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes. Scientific Reports (2019) 9: 11118. (doi:10.1038/s41598-019-47250-0)
- Righetti L., Fenclova M., Dellafiora L., Hajslova J., Stranska-Zachariasova M., Dall'Asta Ch.: High resolution-ion mobility mass spectrometry as an additional powerful tool for structural characterization of mycotoxin metabolites. Food Chemistry (2018) 245: 768-774. (doi: 10.1016/j.foodchem.2017.11.113)
Projects
- 8E18B045: New mask masked ’Fusarium mycotoxins found in malt and beer, clarification of their origin and proposal of strategies for their minimization (Ministry of Education, Youth and Sports)
Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.
- 20-14649S: Pulsed electric field as an innovative tool to reduce the occurrence of micromycetes of the genus Fusarium and mycotoxins in the barley-malt-beer chain (Czech Science Foundation)
Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.
- 16-06008S: A novel comprehensive strategy for assessment of biological effects elicited by mixtures of chemicals occurring foods and food supplements (Czech Science Foundation)
Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.
Cannabinoids
Plant cannabinoids (phytocannabinoids) are a group of structurally diverse bioactive secondary metabolites occurring in Cannabis sativa L. plants. C. sativa and cannabinoids are now increasingly popular in connection with the production and distribution of "healthy foods" and cannabis-based dietary supplements. Besides the most well-known psychotropic tetrahydrocannabinol (THC), being produced by certain C. sativa varieties (in particular C. sativa L. var. indica), tens up to hundreds of other phytocannabinoids with numerous positive biological effects (antioxidant, anti-inflammatory, immunomodulatory, etc.) are the subject of our current interdisciplinary research. In addition to development of analytical methods for efficient separation and sensitive detection of cannabinoids in various cannabis varieties and derived products, our working group collaborates also on determination of biological availability and biological endpoints of these compounds.
It should be noted that in addition to natural phytocannabinoids, the subject of our interest are also so-called synthetic cannabinoids, substances of completely different structure, but similar pharmacological effect such as THC. Their occurrence in food has recently been observed in the Czech Republic.
Publications
- Benes F., Fenclova M., Peukertova P., Binova Z., Dzuman Z., Hajslova J.: Determination of seventeen phytocannabinoids in various matrices by UHPLC-HRMS/MS. LCGC Europe (2020) 33(1): 8-16. Fulltext
- Vaclavik L., Benes F., Fenclova M, Hricko J., Krmela A., Svobodova V., Hajslova J., Mastovska K.: Quantitation of Cannabinoids in Cannabis Dried Plant Materials, Concentrates, and Oils Using Liquid Chromatography-Diode Array Detection Technique with Optional Mass Spectrometric Detection: Single-Laboratory Validation Study, First Action 2018.11. Journal of AOAC International (2019) 102(6): 1822-1833. (doi: 10.5740/jaoacint.18-0426)
Projects
- TJ02000238: Development of innovative analytical strategies usable for checking the safety and authenticity of food and food raw materials (Technology Agency of the Czech Republic)
Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.
- FV40103: Biotechnology of cannabis cultivation for the production of CBD (Ministry of Industry and Trade)
Principal Investigator at UCT Prague: prof. Ing. Jana Hajšlová, CSc.
- TN01000048/04: Biorefining as a circulating technology - valorization of plant biomass by biorefining processes (Technology Agency of the Czech Republic)
Principal Investigator at UCT Prague: prof. Ing. Jana Hajšlová, CSc.
Head of the working group:
doc. Ing. Milena Stránská, Ph.D.
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Researchers:
Ing. Zbyněk Džuman, Ph.D.
Ing. Marie Zlechovcová, Ph.D.
Ing. Nela Průšová, Ph.D.
PhD. students:
Ing. Adam Behner
Ing. Ondřej Brabenec
Ing. Tereza Doležalová
CANNABINOIDS
Researchers:
Ing. Marie Zlechovcová, Ph.D.
Ing. František Beneš, Ph.D.
PhD. students:
Ing. Zuzana Bínová
Ing. Tereza Jaegerová
Professor:
prof. Ing. Jana Hajšlová, CSc.
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