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Technická 5
166 28 Prague 6 – Dejvice
IČO: 60461373 / VAT: CZ60461373
Czech Post certified digital mail code: sp4j9ch
Copyright: UCT Prague 2015
Information provided by the Department of International Relations and the Department of R&D. Technical support by the Computing Centre.
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[obsah] => DEPARTMENT OF FOOD ANALYSIS AND NUTRITION is a part of the Faculty of Food and Biochemical Technology. The research projects are mainly focused on food and feed quality, authenticity & safety related issues; investigations concerned with the impact of environmental conditions on the human food chain are also included. Special attention is paid to studies concerned with food components interactions / breakdown which may result in changes of nutritional value and/or sensory properties. In the recent years, interdisciplinary ‘omics’-based research aimed at the assessment of in vivo / in vitro effects induced by biologically active compounds, both beneficial and toxic, has been initiated.
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Our Department contributes to teaching of following Study Programmes:
Bachelor Study Programme
Chemistry and Technology, specialization Food Chemistry and Technology
Our teachers participate in learning of following subjects of this programme:
2nd year
Sensory Analysis (SIS or EMIL)
3rd year
Analysis of Food and Natural Products: Laboratory (SIS or EMIL)
Human Nutrition and Nutritional Policy (SIS or EMIL)
Food and Natural Products Analysis (SIS or EMIL)
Master Study Programmes
Biotechnology and Food Science
Our teachers participate in learning of following subjects of this programme:
1st year
Reaction Mechanisms in Food Chemistry (SIS or EMIL)
Special Food Analysis (SIS or EMIL)
Chemical Food Safety (SIS or EMIL)
Analysis of Bioactive Compounds (SIS or EMIL)
Control of Food Raw Materials and Commodities: Laboratory (SIS or EMIL)
2nd year
Isolation and Separation Methods (SIS or EMIL)
Doctoral Study Programme
Food and Natural Products
List of available PhD topics here
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[obsah] => Expert services and/or collaboration within common research projects are offered in the following areas:
A. FOOD/FEED CHEMICAL SAFETY, HUMAN EXPOSURE, AND FORENSIC ISSUES
Development of advanced methods for analysis of multiple contaminants and their metabolites in food, feed, biological and environmental matrices; investigation of preventive measures and mitigation strategies:
- Mycotoxins and natural plant toxins
- Pesticide / veterinary drugs residues
- POPs and other industrial contaminants
- Packaging contaminants / migrants
- Processing contaminants, antinutritive substances
- Nanoparticles
- ´Emerging´ contaminants
B. FOOD QUALITY ATTRIBUTES AND AUTHENTICATION; BIOPROSPECTION
Implementation of novel approaches for characterization and classification of:
- Metabolome / foodome: fingerprinting and/or profiling methods employing high resolution MS (ambient, LC, GC); advanced data processing; specific markers´ identification
- Biologically active compounds: non-target screening for ‘unknowns’ in plants / microorganisms; identification based on cutting-edge mass spectrometric techniques; assessment of chemical cocktails in combination with bioactivity testing
- Flavours / odours: combination of instrumental and sensory analysis; assessment based on the combination of comprehensive GC and olfactometry
TRAINING AND STUDY STAYS are offered to PhD students / postdoc young researchers interested in the above areas.
The UCT Prague closely cooperates with EU Reference Laboratories (EURLs) network in the field of QA/QC strategies, interlaboratory validation studies, reference materials and traceability of chemical measurements.
‘ACCREDITED TESTING AND METROLOGICAL LABORATORY’ of the Department of Food Analysis and Nutrition performs according to the International standard ISO/IEC 17025:2005; accreditation was provided by the Czech Accreditation Institute, signatory of the ILAC-MRA. For an external QC, the laboratory regularly participates in the proficiency testing (FAPAS, EU PT, IRMM, IAEA, etc.).
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[seo_title] => Organic pollutants in food, environment and human biomonitoring studies
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[obsah] => Organic pollutants in food, environment and human biomonitoring studies
Industrial contaminants in the food chain
Human population uses a number of chemicals on a daily basis that can be released into the environment, where they can have negative effects and persist for a long time. These compounds can be found in various environmental compartments, including water, air, or soil, which together with sediments can represent a significant reservoir of persistent substances. Undesirable substances penetrate into environment by various ways, including atmospheric deposition, the use of contaminated water for irrigation or through accidental spills.
Our research group has been involved in the analysis of environmental contaminants for a long time. From the group of persistent organic pollutants (POPs), we focus on brominated flame retardants. (BFR), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), chlorinated paraffins (CPs), perfluoroalkylated substances (PFAS), but also polycyclic aromatic hydrocarbons (PAHs), phthalates, UV filters, organophosphate flame retardants (OPFRs). In many studies, we monitor these chemicals not only in food and food supplements, but also in environmental compartments such as air, dust, sediments, soil, water, etc. Recently, we have been analyzing these compounds in food contact materials and other object of everyday use as they represent significant sources of human exposure to these chemicals. Within the research projects, we develop the required multianalytical methods, in which gas or liquid chromatography coupled with mass spectrometry is used as an instrumental technique.
Publications
- Drabova L., Dvorakova D., Urbancova K., Gramblicka T., Hajslova J., Pulkrabova J.: Critical Assessment of Clean-Up Techniques Employed in Simultaneous Analysis of Persistent Organic Pollutants and Polycyclic Aromatic Hydrocarbons in Fatty Samples. Toxics (2022), 10 (1),12. (doi: 10.3390/toxics10010012)
- Jurikova M., Dvorakova D., Pulkrabova J.: The occurrence of perfluoroalkyl substances (PFAS) in drinking water in the Czech Republic: a pilot study. Environmental Science and Pollution Research (2022) published (doi: 10.1007/s11356-022-20156-7)
- Tomasko J., Hrbek V., Kourimsky T., Stupak M., Hajslova J., Pulkrabova J.: Are fish oil-based dietary supplements a significant source of exposure to chlorinated paraffins? Science of the Total Environment (2022) 833, 155137. (doi: 10.1016/j.scitotenv.2022.155137)
- Tomasko J., Stupak M., Hajslova J., Pulkrabova J.: Application of the GC-HRMS based method for monitoring of short- and medium-chain chlorinated paraffins in vegetable oils and fish. Food Chemistry (2021) in press. (doi: 10.1016/j.foodchem.2021.129640)
- Polachova A., Gramblicka T., Parizek O., Sram R.J., Stupak M., Hajslova J., Pulkrabova J.: Estimation of human exposure to polycyclic aromatic hydrocarbons (PAHs) based on the dietary and outdoor atmospheric monitoring in the Czech Republic. Environmental Research (2020) 182: 108977. (doi: 10.1016/j.envres.2019.108977)
Projects
- GAČR - Vliv nových chlorovaných kontaminantů na adipogenezi, 21-19437S, 01/2021 – 12/2023
- Horizon 2020 - PAPILLONS - Plastic in Agricultural Production: Impacts, Lifecycles and Long-term Sustainability, 101000210, 6/2021 - 5/2025
- EFSA - Screening for emerging chemical risks in the food chain, OC/EFSA/SCER/2020/02, 02/2021 – 01/2024
Biomonitoring, exposom
Today, humans are exposed to mixtures of chemicals that are released into the environment from various commercial and industrial applications. Some of them can have an adverse effect on human health. Therefore, it is necessary to monitor the quality of the environment and to assess its impact on humans. For this purpose, human biological monitoring (biomonitoring) is applied and provides, which provides data on the amount of chemicals and their metabolites in the body by analyzing suitable biological samples, such as blood serum / plasma, urine, breast milk, etc.
|
„Human Biological Monitoring“, Zielhuis, 1984
|
Our research group has been involved in European biomonitoring for many years. We develop multianalytical procedures based on chromatography and mass spectrometry, which meet the requirements of ultratrace analysis for the determination of different groups of environmental contaminants in one analysis. The group of persistent organohalogenated pollutants are represented by brominated flame retardants, polychlorinated biphenyls, chlorinated pesticides, chlorinated paraffins, perfluoroalkylated compounds, but also polycyclic aromatic hydrocarbons, phthalates, UV filters, organophosphate flame retardants, including their metabolites.
Publications
- Nübler S., Lopez M. E., Castano A., Mol H. G. J., Haji-Abbas-Zarrabi K., Schäfer M., Hajslova J., Dvorakova D., Antignac J.-P., Koch H. M., Huag L. S., Vorkamp K., Göen T.: Interlaboratory Comparison Investigations (ICIs) and External Quality Assurance Schemes (EQUASs) for human biomonitoring of perfluoroalkyl substances (PFASs) in serum as part of the quality assurance programme under HBM4EU. Science of The Total Environment (2022) 847: 157481 (doi: 10.1016/j.scitotenv.2022.157481)
- Ambroz A., Rossner Pavel Jr., Rossnerova A., Honkova K., Milcova A., Pastorkova A., Klema J., Pulkrabova J., Parizek O., Vondraskova V., Zelenka J., Vrzackova N., Schmuczerova J., Topinka J., Sram R.J.: Oxidative Stress and Antioxidant Response in Populations of the Czech Republic Exposed to Various Levels of Environmental Pollutants. Environmental Research and Public Health (2022). 19, 3609. (doi: 10.3390/ijerph19063609)
- Cerna M., Grafnetterova A.P., Dvorakova D., Pulkrabova J., Maly M., Janos T., Vodrazkova N., Tupa Z., Puklova V.: Biomonitoring of PFOA, PFOS and PNFNA in human milk from Czech Republic, time trends and estimation of infant’s daily intake.Environmental Research (2020) in press. (doi: 1016/j.envres.2020.109763)
- Dvorakova D., Pulkrabova J., Gramblicka T., Polachova A., Buresova M., Hajslova J., López M.E., Castaño A., Nübler S., Haji-Abbas-Zarrabi K., Klausner N., Göen T., Mol H., Koch H.M., Vaccher V., Antignac J.-P., Haug L.S., Vorkamp K.: Interlaboratory Comparison Investigations (ICIs) and External Quality Assurance Schemes (EQUASs) for Flame Retardant Analysis in Biological Matrices: Results from the HBM4EU Project. Environmental Research (2021) 202: 111705. (doi: 10.1016/j.envres.2021.111705)
- Polachova A., Gramblicka T., Bechynska K., Parizek O., Turnerova, Dvorakov, Honkova K., Rossnerova A., Rossner P., Sram R.J., Topinka J., Pulkrabova J.: Biomonitoring of 89 POPs in blood serum samples of Czech city policemen. Environmental Pollution (2021) 291: 118140(doi: 10.1016/j.envpol.2021.118140)
- Urbancova K., Sram R.J., Hajslova J., Pulkrabova J.: Concentrations of Phthalate and DINCH Metabolites in Urine Samples from Czech Mothers and Newborns. Exposure and Health (2021) 14: 17-27 (doi: 10.1007/s12403-021-00415-7)
Projects
- GAČR - Vliv nových chlorovaných kontaminantů na adipogenezi, 21-19437S, 01/2021 – 12/2023
- Horizon Europe - PARC - European Partnership for the Assessment of Risks from Chemicals, HORIZON-HLTH-2021-ENVHLTH-03, No. 101057014, 5/2022 - 4/2029
Head of the working group:
prof. Ing. Jana Pulkrabová, Ph.D.
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Associate professors:
doc. Ing. Darina Dvořáková, Ph.D.
Researchers:
Ing. Lucie Drábová, Ph.D.
Ing. Veronika Svobodová, Ph.D.
Aristeidis Tsagkaris, Ph.D.
Ing. Tomáš Gramblička, Ph.D.
Ing. Jakub Tomáško, Ph.D.
Ph.D. students:
Ing. Ondřej Pařízek
Ing. Veronika Gomersall
BIOMONITORING, EXPOSOM
Associate professors:
doc. Ing. Darina Dvořáková, Ph.D.
Researchers:
Ph.D. students:
Ing. Ondřej Pařízek
Ing. Denisa Pařízková
Ing. Veronika Gomersall