DATA

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Expert services and/or collaboration within common research projects are offered in the following areas:

A. FOOD/FEED CHEMICAL SAFETY, HUMAN EXPOSURE, AND FORENSIC ISSUES

Development of advanced methods for analysis of multiple contaminants and their metabolites in food, feed, biological and environmental matrices; investigation of preventive measures and mitigation strategies:

Mycotoxins and natural plant toxins
Pesticide / veterinary drugs residues
POPs and other industrial contaminants
Packaging contaminants / migrants
Processing contaminants, antinutritive substances
Nanoparticles
´Emerging´ contaminants

B. FOOD QUALITY ATTRIBUTES AND AUTHENTICATION; BIOPROSPECTION

Implementation of novel approaches for characterization and classification of:

Metabolome / foodome: fingerprinting and/or profiling methods employing high resolution MS (ambient, LC, GC); advanced data processing; specific markers´ identification
Biologically active compounds: non-target screening for ‘unknowns’ in plants / microorganisms; identification based on cutting-edge mass spectrometric techniques; assessment of chemical cocktails in combination with bioactivity testing
Flavours / odours: combination of instrumental and sensory analysis; assessment based on the combination of comprehensive GC and olfactometry

TRAINING AND STUDY STAYS are offered to PhD students / postdoc young researchers interested in the above areas.

The UCT Prague closely cooperates with EU Reference Laboratories (EURLs) network in the field of QA/QC strategies, interlaboratory validation studies, reference materials and traceability of chemical measurements.

‘ACCREDITED TESTING AND METROLOGICAL LABORATORY’ of the Department of Food Analysis and Nutrition performs according to the International standard ISO/IEC 17025:2005; accreditation was provided by the Czech Accreditation Institute, signatory of the ILAC-MRA. For an external QC, the laboratory regularly participates in the proficiency testing (FAPAS, EU PT, IRMM, IAEA, etc.).

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Nicolet iS50 FT-IR Spectrometer (Thermo Fisher Scientific, USA)

Description

Fourier transform infrared spectrometer Nicolet TM iS50 (FTIR)
This instrumentation represents Fourier transform infrared spectrometer (FT-IR) with a built-in diamond ATR crystal for measurements using an attenuated total reflection technique. Measurements can be performed in UV-VIS, IR, NIR, and FAR area (without the need of blowing through the device). The instrument is also able to record Raman spectra without any replacement of the system components. Infrared spectroscopy is widely used in both qualitative and quantitative analysis. At the Department of Food Analysis and Nutrition UCT Prague, this instrument is mostly used for determination of the acid value or authentication of various foodstuffs and food supplements (such as oil, butter, margarine, spices, honey, lecithin, oyster mushroom, milk thistle).
Publications:
• Vytejčková S., Gavlasová D., Hajšlová J., Poustka J.: Fourier transform infrared spectroscopy coupled to chemometric tools applied for the authentication of flours made of cereals and pseudo cereals. 7th International Symposium on Recent Advances in Food Analysis, November 3-6, 2015, Prague, Czech Republic
• Vytejčková S., Pohořelá B., Pánek J., Hajšlová J., Poustka J.: Recognition of vegetable oils adulteration and oxidative changes in thermally stressed fats and oils using Fourier transform infrared spectroscopy. 7th International Symposium on Recent Advances in Food Analysis, November 3-6, 2015, Prague, Czech Republic
• Pekárková V., Vassilkova A., Hajšlová J., Poustka J.: Potential of Fourier transform infrared spectroscopy for joint supplements authentication. 7th International Symposium on Recent Advances in Food Analysis, November 3-6, 2015, Prague, Czech Republic
• Poustka J.: Application of mid infrared spectroscopy for food and food supplements authentication. 9th International Symposium on Recent Advances in Food Analysis, November 5-8, 2019, Prague, Czech Republic

Spectrophotometer Cary 60 UV-Vis (Agilent Technologies, USA)

Agilent 1200 Series Rapid Resolution LC system with DAD and FLD detectors (Agilent Technologies, USA)

Description

The liquid chromatography system connected with a diode array detector and a fluorescence detector is mainly used for the analysis of polycyclic aromatic hydrocarbons, carotenoids, amino acids and vitamins (groups B, C and E) in a wide range of foods (fruits, vegetables, teas, cereals, food supplements, hemp products…) and beverages.

Publications:
• Pavelkova P., Krmela A., Schulzova V.: Determination of carotenoids in flowers and food supplements by HPLC-DAD. Acta Chimica Slovaca (2020) 13(1). (doi: 10.2478/acs-2020-0002)
• Bhave A., Schulzova V., Mrnka L., Hajslova J.: Influence of Harvest Date and Postharvest Treatment on Carotenoid and Flavonoid Composition in French Marigold Flowers. Journal of Agricultural and Food Chemistry (2020) 68(30): 7880–7889. (doi: 10.1021/acs.jafc.0c02042)
• Novotny C., Schulzova V., Krmela A., Hajslova J., Svobodova K., Koudela M.: Ascorbic Acid and Glucosinolate Levels in New Czech Cabbage Cultivars: Effect of Production System and Fungal Infection. Molecules (2018) 23(8):1855 (doi: 10.3390/molecules23081855)

Acquity UPLC with Evaporative Light Scattering (ELS) detector (Waters, USA)

FCPC® A Kromaton (Rousselet Centrifugation)

Description

Fast centrifugal partitioning chromatography FCPC® A Kromaton coupled with peripheral system puriFlash®4250 (Interchim)
This instrumentation consists of a fast centrifugal chromatography (FCPC® A Kromaton) with a rotor volume of 1000 ml and a peripheral system puriFlash®4250 (Interchim), which includes a pump, injection valve, 50 ml injection loop, PDA detector (200 – 600 nm) and fraction collector. The separation is based on the different affinity of the analytes to the two immiscible solvent mixtures, which represent the stationary and mobile phase. The system is suitable for the separation and isolation of various bioactive compounds, such as phenolics, flavonoids, lignans, alkaloids, and many others.

Main benefits of the FCPC® A Kromaton system

• Large amounts of sample mass can be loaded (up to 50 ml)
• No extraction and purification of target molecules needed prior FCPC
• Suitable even for low-concentrated bioactive compounds • Applicable for a broad spectrum of compounds
At the Department of Food Analysis and Nutrition UCT Prague, this instrument is mainly used for the separation and isolation of bioactive compounds from Cannabis sativa L. extracts.

Halogen Moisture Analyzer HG63 (Mettler Toledo)

Description

The halogen moisture analyzer is suitable for routine determination of moisture content. It is fast (results obtained within minutes) and efficient, and offers very good repeatability even if a small amount of sample is available. The fast speed and good repeatability of the measurement are achieved by a circular halogen lamp and a gold-plated reflector. The results are obtained with resolution of up to 10 ppm MC. The halogen moisture analyzer is mainly used for the determination of the dry matter in plant material.

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GC-MS/MS Agilent 7000B Triple Quadrupole

Gas chromatography coupled to tandem mass spectrometry (triple quadrupole) equipped with electron impact ionization technique is employed for the analysis of pesticide residues in a wide range of foodstuffs (e.g. fruit, vegetable, tea, cereals). This instrumentation allows to measure more than 300 pesticide residues in less than 30 minutes at ultra-trace concentrations in one run. This system is also equipped with a JetClean function for self-cleaning ion source with hydrogen.

Publications

Drabova L., Alvarez-Rivera G., Suchanova M., Schusterova D., Pulkrabova J., Tomaniova M., Kocourek V., Chevallier O., Elliot Ch., Hajslova J.: Food fraud in oregano: pesticide residues as adulteration markers. Food Chemistry (2019) 276:726-734. (doi:10.1016/j.foodchem.2018.09.143)

Cajka T., Sandy C., Bachanova V., Drabova L., Kalachova K., Pulkrabova J., Hajslova J.: Streamlining sample preparation and gas chromatography-tandem mass spectrometry analysis of multiple pesticide residues in tea. Anal. Chim. Acta (2012) 743:51–60. (doi: 10.1016/j.aca.2012.06.051)

GC-MS/MS Agilent 7000B Triple Quadrupole

Gas chromatography coupled to tandem mass spectrometry (triple quadrupole) is particularly used for the analysis of environmental contaminants (e.g. polychlorinated biphenyls, flame retardants, organochlorine pesticides). Applications allow multi-detection analysis in a wide range of environmental (e.g. soil or atmosphere), food (e.g. meat, fat, fruit or vegetable) and biological (e.g. human breast milk or human blood serum) samples. This second triplequad system is also possible to operate in chemical ionization suitable particularly for the analysis of halogenated compounds and it is equipped with fully automated device for solid phase microextraction (CTC Pal) for the analysis of volatile compounds.

Publications

Polachova A., Gramblicka T., Parizek O., Sram R.J., Stupak M., Hajslova J., Pulkrabova J.: Estimation of human exposure to polycyclic aromatic hydrocarbons (PAHs) based on the dietary and outdoor atmospheric monitoring in the Czech Republic. Environmental Research (2020) 182: 108977. (doi: 10.1016/j.envres.2019.108977)

Logerova H., Tuma P., Stupak M., Pulkrabova J., Dlouhy P.: Evaluation of the burdening on the Czech population by brominated flame retardants. International Journal of Environmental Research and Public Health (2019) 16(21) 4105. (doi: 10.3390/ijerph16214105 )

Pulkrabova J., Cerny J., Szakova J., Svarcova A., Gramblicka T., Hajslova J., Balik J., Tlustos P.: Is the long-term application of sewage sludge turning soil into a sink for organic pollutants?: evidence from field studies in the Czech Republic. Journal of Soils and Sediments (2019) 19: 2445-2458. (doi:10.1007/s11368-019-02265-y)

Svarcova A., Lankova D., Gramblicka T., Stupak M., Hajslova J., Pulkrabova J.: Integration of five groups of POPs into one multi-analyte method for human blood serum analysis: An innovative approach within biomonitoring studies. Science of The Total Environment (2019) 667: 701-709. (doi: 10.1016/j.scitotenv.2019.02.336)

Szakova J., Pulkrabova J., Cerny J., Mercl F., Svarcova A., Gramblicka T., Najmanova J., Tlustos P., Balik J.: Selected persistent organic pollutants (POPs) in the rhizosphere of sewage sludge-treated soil: Implications for the biodegradability of POPs. Archives of Agronomy and Soil Science (2019) 65(7): 994-1009. (doi:10.1080/03650340.2018.1543945)

Pulkrabova J., Stupak M., Svarcova A., Rossner P., Rossnerova A., Ambroz A., Sram R., Hajslova J.: Relationship between atmospheric pollution in the residential area and concentrations of polycyclic aromatic hydrocarbons (PAHs) in human breast milk. Science of the Total Environment (2016) 562: 640-647. (doi: 10.1016/j.scitotenv.2016.04.013)

Kalachova K., Cajka T., Sandy C., Hajslova J., Pulkrabova J.: High throughput sample preparation in combination with gas chromatography coupled to triple quadrupole tandem mass spectrometry (GC-MS/MS): a smart procedure for (ultra)trace analysis of brominated flame retardants in fish. Talanta (2013) 105:109–116.(doi: 10.1016/j.talanta.2012.11.073)

Kalachova K., Pulkrabova J., Cajka T., Drabova L., Stupak M., Hajslova J.: Gas chromatography–triple quadrupole tandem mass spectrometry: A powerful tool for the (ultra)trace analysis of multi-class environmental contaminants in fish and fish feed. Anal. Bioanal. Chem., (2013) 405: 7803–7815 (doi: 10.1007/s00216-013-7000-4)

GC-MS/MS Agilent 7000C Triple Quadrupole

Gas chromatography coupled to tandem mass spectrometry (triple quadrupole) is an alternative technique to a system Agilent 7000B for the analysis of environmental contaminants (e.g. polychlorinated biphenyls, flame retardants, organochlorine pesticides). Applications allow multi-detection analysis in a wide range of environmental (e.g. soil or atmosphere), food (e.g. meat, fat, fruit or vegetable) and biological (e.g. human breast milk or human blood serum) samples. By Agilent 7000C system we can achieved lower limits of quantification for target analytes compared to the system Agilent 7000B. This system is also equipped with a JetClean function for self-cleaning ion source with hydrogen.

GC-MS/MS Agilent 7010 Triple Quadrupole

The last generation of gas chromatography coupled to tandem mass spectrometry (triple quadrupole) is employed for the analysis of pesticide residues in a wide range of foodstuffs (e.g. fruit, vegetable, tea, cereals) and environmental samples. This instrument allows to measure more than 300 pesticide pesticides in less than 30 minutes in one run. Its high-efficiency electron impact ion source produces at least 20 times as many ions as the previous generation, improving the efficiency of the entire workflow.

GC-HRMS Pegasus HRT (LECO)

Gas chromatography coupled to high resolution mass spectrometry (time of flight analyzer) enable resolution of 50,000 FWHM and mass accuracies less than 1 ppm is used for target and non-target analysis of volatile and semi-volatile compounds. This technique is equipped with a fully automated device for solid phase microextraction (Gerstel). GC-HRMS Pegasus HRT is employed for non-target analysis of volatiles in variable samples, for a routine analysis of furans or dithiocarbamates and for a practical training of students.

Publications

Gracka A., Raczyk M., Hradecky J., Hajslova J., Jeziorski S., Karlovits G., Michalak B., Bąk N. and Jeleń H.: Volatile compounds and other indicators of quality for cold-pressed rapeseed oils obtained from peeled, whole, flaked, and roasted seeds. European Journal of Lipid Science Technology (2017) 119 (10). (doi:10.1002/ejlt.201600328)

Hradecky J., Kludska E., Belkova B., Wagner M., Hajslova, J.: Ohmic heating: A promising technology to reduce furan formation in sterilized vegetable and vegetable/meat baby foods. Innovative Food Science and Emerging Technologies (2017) 43: 1-6. (doi: 10.1016/j.ifset.2017.07.018)

GC-MS Agilent 5973 Single Quadrupole

Gas chromatography coupled to mass spectrometry (single quadrupole) is particularly used in student laboratory courses. In the courses, students learn detail functions of this instrumentation and try some GC-MS application (e.g. the determination of volatile compounds in spices or the alcoholic beverages quality determination).

Publications

Stupak M, Kocourek V., Kolouchova I., Hajslova J.: Rapid approach for the determination of alcoholic strength and overall quality check of various spirit drinks and wines using GC–MS. Food Control (2017) 80: 307-313 (doi: 10.1016/j.foodcont.2017.05.008)

GCxGC-MS Pegasus® 4D

Gas chromatography enabling two dimensional separation coupled to mass spectrometry (time of flight analyzer) is particularly used for the determination of volatile and semi-volatiles compounds in extremely complex matrixes (e.g. mineral oils). This technique has fully automated device for solid phase microextraction (Gerstel). Other applications employing GCxGC-MS Pegasus® 4D are the analysis of environmental contaminants (e.g. polychlorinated biphenyls, flame retardants or organochlorine pesticides) and terpenoic compounds in cannabis and cannabis products.

Publications

Drabova L., Pulkrabova J., Kalachova K., Tomaniova M., Kocourek V., Hajslova J.: Polycyclic aromatic hydrocarbons (PAHs) and halogenated persistent organic pollutants (POPs) in canned fish and seafood products: smoked versus non-smoked products. Food Addit. Contam. A (2013) 30:5152–527. (doi: 10.1080/19440049.2012.755645)

Drabova L., Tomaniova M., Kalachova K., Kocourek V., Hajslova J., Pulkrabova J.: Application of solid phase extraction and two-dimensional gas chromatography coupled with time-of-flight mass spectrometry for fast analysis of polycyclic aromatic hydrocarbons in vegetable oils. Food Control (2013) 33: 489–497. (doi: 10.1016/j.foodcont.2013.03.018)

Drabova L., Pulkrabova J., Kalachova K., Tomaniova M., Kocourek V., Hajslova J.: Rapid determination of polycyclic aromatic hydrocarbons (PAHs) in tea using Two-Dimensional Gas Chromatography coupled with Time of Flight Mass Spectrometry. Talanta (2012) 100:207–216. (doi:10.1016/j.talanta.2012.07.081)

Kalachova K., Pulkrabova J., Cajka T., Drabova L., Hajslova J.: Implementation of comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the simultaneous determination of halogenated contaminants and polycyclic aromatic hydrocarbons in fish. Anal. Bioanal. Chem. (2012) 403:2813–2824. (doi: 10.1007/s00216-012-6095-3)

Drábová L., Pulkrabová J., Kalachová K., Hradecký J., Suchanová M., Tomaniová M., Kocourek V., Hajšlová J.: Novel approaches to determination of PAHs and halogenated POPs in canned fish. Czech J. Food Sci. (2011) 29:498–507

Kalachova K., Pulkrabova J., Drabova L., Cajka T., Kocourek V., Hajslova J.: Simplified and rapid determination of polychlorinated biphenyls, polybrominated diphenyl ethers, and polycyclic aromatic hydrocarbons in fish and shrimps integrated into a single method. Anal. Chim. Acta (2011) 707:84–91. (doi: 10.1016/j.aca.2011.09.016)

GC-HRMS Agilent 7200b

Agilent 7200b is a system consists of gas chromatography and high resolution tandem mass spectrometry (quadrupole-time of flight analyzer). This instrumentation is mostly applied for non-target analysis (e.g. determination of Scotch whisky authenticity) as well as for target analysis (e.g. chlorinated paraffins in foodstuffs and biological samples, pesticide residues in foodstuffs, terpenoic compounds in cannabis and cannabis products and determination of spirits quality). This instrument is also equipped with fully automated device for solid phase microextraction and chemical (positive/negative) ionization. Agilent 7200b is also used in student laboratory courses.

Publications

Stupak M., Goodall I., Tomaniova M., Pulkrabova J., Hajslova J.: A novel approach to assess the quality and authenticity of Scotch Whisky based on gas chromatography coupled to high resolution mass spectrometry. Analytica Chimica Acta (2018) 1042:60-70. (doi: 10.1016/j.aca.2018.09.017)

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The instrumentation is utilized at the Department of Analytical Chemistry and in the field of metabolomic analysis, ultra-trace analysis, and it is also used for the identification of unknown compounds.

Liquid chromatograph Vanquish Horizon hyphenated to mass spectrometer Exploris 240

Ultra-high performance liquid chromatograph Vanquish Horizon with high resolution tandem mass spectrometer Exploris 240 (U-HPLC‒HRMS/MS) is a modern, user-friendly instrument enabling chromatographic separation at very high operating pressures, ionization using electrospray (ESI), or atmospheric pressure chemical ionization (APCI). Detection is performed using a high-resolution orbitrap mass analyzer with a resolution of up to 240,000 FWHM. High precision of the detected ions m/z is achieved through the built-in autocalibration module (EASY-IC) that can be utilized before and during the analysis. The measuring PC and the available powerful data processing station are equipped with specialized software for handling extensive data.

U-HPLC‒MS/MS (Acquity UPLC – QTRAP 5500)

1) QTRAP 5500 (originál)

Hyphenation of ultra-high performance liquid chromatograph Acquity UPLC (Waters) and tandem mass spectrometer QTRAP 5500 (Sciex) equipped with quadrupole and linear ion trap mass analyzers and electrospray ionization (ESI) interface represents a ‘standard’ instrumentation for quantitative analysis of known compounds at low concentration levels, provides high degree of selectivity (MS2) and allows the possibility of additional confirmation of selected compounds (MS3). The instrument is used for detection of mycotoxins and residues of polar pesticides and pesticides in water and also for laboratory teaching.

Publications

Dzuman Z., Vaclavikova M., Polisenska I., Veprikova Z., Fenclova M., Zachariasova M., Hajslova J.: Enzyme linked immunosorbent assay in analysis of deoxynivalenol: Investigation of impact of sample matrix on results accuracy. Analytical and Bioanalytical Chemistry 406 (2014): 505-514. (doi: 10.1007/s00216-013-7463-3)

Dzuman Z., Zachariasova M., Lacina O., Veprikova Z., Slavikova P., Hajslova J.: A rugged high-throughput analytical approach for the determination and quantification of multiple mycotoxins in complex feed matrices. Talanta 121 (2014): 263–272. (doi: 10.1016/j.talanta.2013.12.064)

Zachariasova M., Dzuman Z., Veprikova Z., Hajkova K., Jiru M., Vaclavikova M., Zachariasova A., Pospichalova M., Florian M., Hajslova J.: Occurrence of multiple mycotoxins in European feedingstuffs, assessment of dietary intake by farm animals. Animal Feed Science and Technology 193 (2014): 124–140. (doi: 10.1016/j.anifeedsci.2014.02.007)

Vaclavikova M., Dzuman Z., Lacina O., Fenclova M., Veprikova Z., Zachariasova M., Hajslova J.: Monitoring survey of patulin in a variety of fruit-based products using a sensitive UHPLC-MS/MS analytical procedure. Food Control 47 (2015): 577–584. (doi: 10.1016/j.foodcont.2014.07.064)

Veprikova Z., Zachariasova Z., Dzuman Z., Zachariasova A., Fenclova M., Slavikova P., Vaclavikova M., Mastovska K., Hengst D., Hajslova J.: Mycotoxins in plant-based dietary supplements: hidden health risk for consumers. Journal of Agricultural and Food Chemistry 63 (2015): 6633–6643. (doi: 10.1021/acs.jafc.5b02105)

Chrpova J., Sip V., Salava J., Palicova J., Stockova L., Dzuman Z., Hajslova J.: Occurrence of Fusarium species and mycotoxins in wheat grain collected in the Czech Republic. World Mycotoxin Journal 9 (2016): 317–327. (doi: 10.3920/WMJ2015.1917)

Dzuman Z., Zachariasova M., Vaclavikova M., Tomaniova M., Veprikova Z., Slavikova P., Hajslova J.: Fate of free and conjugated mycotoxins within the production of distiller’s dried grains with solubles (DDGS). Journal of Agricultural and Food Chemistry 64 (2016): 5085–5092. (doi: 10.1021/acs.jafc.6b00304)

U-HPLC‒MS/MS (Agilent 1290 Infinity II – QTRAP 6500+)

2) QTRAP 6500+ (originál)

Ultra-high performance liquid chromatograph Agilent 1290 Infinity II (Agilent Technologies) and tandem mass spectrometer QTRAP 6500+ (Sciex) equipped with quadrupole and linear ion trap mass analyzers and electrospray ionization (ESI) interface is a new instrument suitable for quantitative analysis of known compounds allowing to achieve high degree of selectivity within routine analysis (MS2) with the possibility of additional confirmation (MS3). The instrument is used for determination of compounds at trace and ultra-trace levels – toxic plant alkaloids, metabolites of environmental contaminants and residues of polar pesticides. It is also equipped with UV and fluorescence detectors finding application e.g. for detection of polycyclic aromatic hydrocarbons.

Publications

Dzuman Z., Jonatova P., Stranska-Zachariasova M., Prusova N., Brabenec O., Novakova A., Fenclova M., Hajslova J.: New liquid chromatography - tandem mass spectrometry method for accurate and sensitive determination of 33 pyrrolizidine and 21 tropane alkaloids in plant-based food matrices. Journal of Chromatography A (2020), under review

U-HPLC‒HRMS (Acquity UPLC – Exactive)

3) Exactive (originál)

Hyphenation of ultra-high performance liquid chromatograph Acquity UPLC (Waters) and high resolution mass spectrometer Exactive (Thermo Scientific) equipped with orbital ion trap mass analyzer utilizes widespread ambient electrospray ionization (ESI), atmospheric pressure chemical ionization (APCI) as well as direct analysis in real time (DART) without chromatographic separation. The instrument operating in full-spectral acquisition mode is used for quantitative analysis of opium alkaloids, MCPD esters and cannabinoids and non-targeted analysis for authentication purposes. It is also used for laboratory teaching.

Publications

Vaclavik L., Zachariasova M., Hrbek V., Hajslova J.: Analysis of multiple mycotoxins in cereals under ambient conditions using direct analysis in real time (DART) ionization coupled to high resolution mass spectrometry. Talanta 82 (2010): 1950-1957. (doi: 10.1016/j.talanta.2010.08.029)

Malachova A., Dzuman Z., Veprikova Z., Vaclavikova M., Zachariasova M., Hajslova J.: Deoxynivalenol, deoxynivalenol-3-glucoside, and enniatins: the major mycotoxins found in cereal-based products on the Czech market. Journal of Agricultural and Food Chemistry 59 (2011): 12990-12997. (doi: 10.1021/jf203391x)

Zachariasova M., Vaclavikova M., Lacina O., Vaclavik L., Hajslova J.: Deoxynivalenol oligoglycosides: new "masked" Fusarium toxins occurring in malt, beer, and breadstuff. Journal of Agricultural and Food Chemistry 60 (2012): 9280-9291. (doi: 10.1021/jf302069z)

Moravcova E., Vaclavik L., Lacina O., Hrbek V., Riddelova K., Hajslova J.: Novel approaches to analysis of 3-chloropropane-1,2-diol esters in vegetable oils. Analytical and Bioanalytical Chemistry 402 (2012): 2871-2883. (doi: 10.1007/s00216-012-5732-1)

Rubert J., Dzuman Z., Vaclavikova M., Zachariasova M., Soler C., Hajslova J.: Analysis of mycotoxins in barley using ultra high liquid chromatography high resolution mass spectrometry: comparison of efficiency and efficacy of different extraction procedures. Talanta 99 (2012): p. 712–719. (doi: 10.1016/j.talanta.2012.07.010)

Hrbek V., Vaclavik L., Elich O., Hajslova J.: Authentication of milk and milk-based foods by direct analysis in real time ionization-high resolution mass spectrometry (DART-HRMS) technique: a critical assessment. Food Control 36 (2014): 138-145. (doi: 10.1016/j.foodcont.2013.08.003)

Hrbek V., Rektorisova M., Chmelarova H., Ovesna J., Hajslova J.: Authenticity assessment of garlic using a metabolomic approach based on high resolution mass spectrometry. Journal of Food Composition and Analysis 67 (2018): 19-28. (doi: 10.1016/j.jfca.2017.12.020)

U-HPLC‒HRMS/MS (UltiMate 3000 – Q-Exactive Plus)

4) Q-ExactivePlus (originál)

Modern technology of the instrument combining ultra-high performance liquid chromatograph UltiMate 3000 (Thermo Scientific) and high resolution tandem mass spectrometer Q-Exactive Plus (Thermo Scientific) equipped with quadrupole and orbital ion trap mass analyzers with characteristic unique mass accuracy (m/z) allows full-spectral acquisition and/or selection of precursor ions and fragmentation. Utilization of both electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) is possible. It is used for quantitative and qualitative determination of cannabinoids, mycotoxins, toxic plant alkaloids and residues of pesticides and also finds application in authentication studies focused on valuable commodities (wine, olive oil, etc.).

Publications

Dzuman Z., Zachariasova M., Veprikova Z., Godula M., Hajslova J.: Multi–analyte high performance liquid chromatography coupled to high resolution tandem mass spectrometry method for control of pesticide residues, mycotoxins, and pyrrolizidine alkaloids. Analytica Chimica Acta (2015) 863: 29–40. (doi:10.1016/j.aca.2015.01.021 )

Stranska-Zachariasova M., Kastanek P., Dzuman Z., Rubert J., Godula M., Hajslova J.: Bioprospecting of microalgae: proper extraction followed by high performance liquid chromatographic-high resolution mass spectrometric fingerprinting as key tools for successful metabolom characterization. Journal of Chromatography B 1015-1016 (2016): 22-33. (doi: 10.1016/j.jchromb.2016.01.050)

Kosek V., Stranska M., Fenclova M., Ruml T., Vitek L., Hajslova J.: High resolution mass spectrometry based method applicable for a wide range of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors in blood serum including intermediates and products of the cholesterol biosynthetic pathway. Journal of Chromatography A 1489 (2017): 86-94. (doi: 10.1016/j.chroma.2017.01.084)

Belkova B., Hradecky J., Hurkova K., Forstova V., Vaclavik L., Hajslova J.: Impact of vacuum frying on quality of potato crisps and frying oil. Food Chemistry 241 (2018): 54-59. (doi: 10.1016/j.foodchem.2017.08.062)

Jiru M., Stranska-Zachariasova M., Dzuman Z., Hurkova K., Tomaniova M., Stepan R., Cuhra P., Hajslova J.: Analysis of phosphodiesterase type 5 inhibitors as possible adulterants of botanical-based dietary supplements: extensive survey of preparations available at the Czech market. Journal of Pharmaceutical and Biomedical Analysis 164 (2019): 713-724. (doi: 10.1016/j.jpba.2018.11.007)

Benes F., Fenclova M., Peukertova P., Binova Z., Dzuman Z., Hajslova J.: Determination of seventeen phytocannabinoids in various matrices by UHPLC-HRMS/MS. LCGC Europe 33 (2020): 8-16

Acquity UPLC liquid chromatograph coupled with with Xevo TQ-S mass spectrometer (LC-MS/MS)

This is a highly sensitive tandem mass spectrometer, which is typically used for the determination of substances even at ultra-trace concentrations. This sensitive universal detector coupled with ultra- high-performance liquid chromatography is a suitable tool for the analysis of a wide range of chemicals in various types of matrices, not only in food, but also in environmental and biomonitoring samples. The mass spectrometer is equipped with an electrospray ion source and the analysis of ions is performed using a triple quadrupole by measuring the characteristic parent and daughter ions of the monitored analytes.

Examples of applications

Analysis of a wide spectrum of pesticide residues (more than 400 substances in one run), especially in fruits and vegetables, but also baby food, cereals and other food ingredients.
Analysis of environmental contaminants, such as perfluoralkylated subsatces or metabolites of polycyclic aromatic hydrocarbons or phthalates in biological matrices and environmental samples.
Analysis of acrylamide - a process contaminant formed during the heat treatment of food, typically determined in samples of biscuits, chips, bread or coffee.

Publications

Urbancova K., Dvorakova D., Gramblicka T., Sram R.J., Hajslova J., Pulkrabova J.: Comparison of polycyclic aromatic hydrocarbon metabolite concentrations in urine of mothers and their newborns. Science of the Total Environment (2020) 723:138116 (doi: 10.1016/j.scitotenv.2020.138116)

Drabova L., Alvarez-Rivera G., Suchanova M., Schusterova D., Pulkrabova J., Tomaniova M., Kocourek V., Chevallier O., Elliot Ch., Hajslova J.: Food fraud in oregano: pesticide residues as adulteration markers. Food Chemistry (2019) 276:726-734. (doi:10.1016/j.foodchem.2018.09.143)

Urbancova K., Lankova D., SramR.J., Hajslova J., Pulkrabova J.: Urinary metabolites of phthalates and di-iso-nonyl cyclohexane-1,2-dicarboxylate (DINCH) – Czech mothers´ and newborns´ exposure biomarkers. Environmental Research (2019), 173: 342-348. (doi: 10.1016/j.envres.2019.03.067)

Urbancova K., Lankova D., Rossner P., Rossnerova A., Svecova V., Tomaniova M., Veleminsky M., Jr., Sram R. J., Hajslova J., Pulkrabova J.: Evaluation of 11 polycyclic aromatic hydrocarbon metabolites in urine of Czech mothers and newborns. Science of the Total Environment (2017) 577: 212–219. (doi: 10.1016/j.scitotenv.2016.10.165)

Lankova D., Urbancova K., Sram R.J., Hajslova J., Pulkrabova J.: A novel strategy for the determination of polycyclic aromatic hydrocarbon monohydroxylated metabolites in urine using ultra-high-performance liquid chromatography with tandem mass spectrometry. Analytical and Bioanalytical Chemistry (2016) 408: 2515–25. (doi: 10.1007/s00216-016-9350-1)

Lankova D., Svarcova A., Kalachova K., Lacina O., Pulkrabova J., Hajslova J.: Multi-analyte method for the analysis of various organohalogen compounds in house dust. Analytica Chimica Acta (2015) 854: 61–69. (doi: 10.1016/j.aca.2014.11.007)

Acquity UPLC liquid chromatograph coupled with Synapt G2 high resolution mass spectrometer (LC-HRMS)

The combination of ultrahigh-performance liquid chromatography with high-resolution mass spectrometry is a unique tool applied especially for metabolomics studies. Measurement of characteristic metabolomics fingerprints allows to control the quality of food, verification the authenticity of food and classification of the analyzed samples according to selected parameters. The mass spectrometer, thanks to its design, allows to perform various scientific experiments. Data from both MS1 and MS/MS modes can be obtained, and last but not least, additional ion separations using ion mobility can be used. This instrument can be operated both under electrospray conditions and chemical ionization at atmospheric pressure. This technique is suitable for the analysis of a wide range of substances present in the examined samples, both non-target analysis and the target analysis of selected compounds are in the application portfolio.

Examples of applications

Metabolomics studies focused on the authentication (confirmation of authenticity) of plant and animal food origin.
Metabolomics fingerprinting for the purpose of classifying samples, for example, according to geographical origin - verification of the declaration of the geographical origin of the food.
Demonstration of the presence of organic nanoparticles in fruit juices.

Publications

Navratilova K., Hrbek V., Kratky F., Hurkova K., Tomaniova M., Pulkrabova J., Hajslova J.: Green tea: authentication of geographic origin based on UHPLC-HRMS fingerprints. Journal of Food Composition and Analysis (2019) 78:121-128. (doi:10.1016/j.jfca.2019.02.004)

Hrbek, V., Rektorisova, M., Chmelarova, H., Ovesna, J., Hajslova, J.: Authenticity assessment of garlic using a metabolomic approach based on high resolution mass spectrometry. Journal of Food Composition and Analysis (2018) 67: 19-28. (doi: 10.1016/j.jfca.2017.12.020 )

Hrbek V., Krtkova V., Rubert J., Chmelarova H., Demnerova K., Ovesna J., Hajslova J.: Metabolomic Strategies Based on High-Resolution Mass Spectrometry as a Tool for Recognition of GMO (MON 89788 Variety) and Non-GMO Soybean: a Critical Assessment of Two Complementary Methods. Food Analytical Methods (2017), 10 (11): 3723-3737. (doi: 10.1007/s12161-017-0929-8)

Krtkova V., Schulzova V., Lacina O., Hrbek V., Tomaniova M., Hajslova J.: Analytical strategies for controlling polysorbate-based nanomicelles in fruit juice. Anal. Bioanal. Chem., (2014) 406: 3909-3918. (doi: 10.1007/s00216-014-7823-7)

Aquity UPC2 supercritical fluid chromatograph coupled with Synapt G2 Si high-resolution mass spectrometer (SFC-HRMS)

Supercritical fluid chromatography is separation technique recently very popular in modern analytical chemistry. Thanks to the use of a supercritical fluid, carbon dioxide, it offers many undeniable advantages. Carbon dioxide is a non-polar mobile phase, thus this chromatographic technique is typically applied primarily for the analysis of non-polar components of the sample. Thanks to the possibility of using polar mobile phase modifiers, the application potential of this technique is extended by the possibility of analysis of medium-polar substances. A high-resolution mass spectrometer which can be operated under various measuring functions (MS1, MS / MS, ion mobility) is used for the detection of a wide spectrum of substances in many scientific studies.

Examples of applications

Metabolomics - lipidomic studies focused on a comprehensive examination of analyzed samples of plant and animal food origin.
Lipidomic fingerprinting in order to control the quality of food products - oils, chocolate and others.
Comprehensive lipidomic analysis of human plasma/serum samples.
Target analysis of natural biologically active substances - cannabinoids in hemp, hemp seeds, hemp oil and other hemp products.
Analysis of contaminants, especially in matrices with a higher fat content - determination of aflatoxins in nuts and other products.

Publications

Hrbek V., Ovesná J., Demnerová K., Hajšlová J.: Využití superkritické fluidní chromatografie pro lipidomické profilování sójového a kravského mléka: Autenticita a detekce falšování. Chemické listy (2015) 109: 518-526.

Acquity UPLC liquid chromatograph coupled with Quattro Premier XE mass spectrometer (LC-MS/MS)

It is one of the first types of tandem mass spectrometers employing at our department, which is currently used to determine substances that are naturally present in higher concentrations in samples. The mass spectrometer includes an electrospray ion source and the analysis of ions is performed using a triple quadrupole by measuring the characteristic parent and daughter ions of the monitored analytes.

Examples of applications

Analysis of water-soluble vitamins, especially B vitamins.
Determination of hyaluronic acid, glucosamine, chondroitin.
Analysis of acrylamide - a process contaminant arising during the heat treatment of food, determined, for example, in samples of biscuits, chips, bread or, for example, coffee.

Publications

Belkova B., Hradecky J., Hurkova K., Forstova V., Vaclavik L., Hajslova J.: Impact of vacuum frying on quality of potato crisps and frying oil. Food Chemistry (2018) 241: 51-59. (doi: 10.1016/j.foodchem.2017.08.062)

Forstova V., Belkova B., Riddellova K., Vaclavik L., Prihoda J., Hajslova J.: Acrylamide formation in traditional Czech leavened wheat-rye breads and wheat rolls. Food Control (2014) 38:221–226. (doi: 10.1016/j.foodcont.2013.10.022)

Acquity UPLC liquid chromatograph coupled with QDa mass spectrometer (LC-MS)

It is a mass spectrometer using a single quadrupole analyzer. QDa is a relatively simple mass spectrometer at relatively low cost. In combination with high-performance liquid chromatography, it is a very efficient and user-friendly tool for routine analyzes, in which it can often replace conventional detectors that surpass their versatility. Due to its simple operation, the instrument is also used for teaching purposes for bachelor students at our faculty as a "first contact" of students with mass spectrometry.

Examples of applications

Determination of additives in food and beverages - especially dyes, sweeteners and preservatives of synthetic origin.
Determination of caffeine - in food and beverages.
Amino acid analysis - monitoring the representation and composition of amino acids in food.

Publications

Jiru M., Stranska-Zachariasova M., Kocourek V., Krmela A., Tomaniova M., Rosmus J., Hajslova J.: Authentication of meat species and net muscle proteins: updating of an old concept. Czech Journal of Food Sciences (2019) 37:205-211. (doi: 10.17221/94/2019-CJFS)

Dionex UltiMate 3000 U-HPLC liquid chromatograph coupled with TripleTOFTM 6600 high resolution tandem mass spectrometric detector (LC-HRMS)

This instrument uses Quadrupole-Time-of-Flight (Q-TOF) technology to measure at high resolution and accurate mass. At the same time, it is possible to select the precursor ion in the quadrupole and obtain MS-MS spectra, thus obtaining a higher selectivity as well as confirming the identity of the analytes by comparison with MS-MS libraries. Electrospray and chemical ionization techniques at atmospheric pressure are available for ionization of substances. SelexIon differential ion mobility technology is also available. It is also possible to connect a conventional diode array detector in series to the device. The device is mainly used for non-target analyzes within metabolomics and identification and confirmation of present substances as well as for the purpose of target search for substances and confirmation of their presence in the analyzed samples.

Examples of applications

Non-target analysis for food authentication and detect of adulteration.
Metabolomics studies in order to classify samples according to the examined parameters (geographical origin; influence of cultivation, harvesting, technological modifications, treatment of samples; variety, etc.)
Multiresidual analysis of pesticides and mycotoxins in food

Publications

Rubert, J.; Lacina, O.; Zachariasova, M.; Hajslova, J. Saffron authentication based on liquid chromatography high resolution tandem mass spectrometry and multivariate data analysis. Food Chemistry 2016, 204, 201–209

Rubert, J.; Lacina, O.; Fauhl-Hassek, C.; Hajslova, J. Metabolic fingerprinting based on high-resolution tandem mass spectrometry: a reliable tool for wine authentication. Analytical and Bioanalytical Chemistry 2014, 406, 6791–6803

Righetti, L.; Rubert, J.; Galaverna, G.; Folloni, S.; Ranieri, R.; Stranska-Zachariasova, M.; Hajslova, J.; Dall'Asta, C. Characterization and discrimination of ancient grains: A metabolomics approach. International Journal of Molecular Sciences 2016, 17, 1217

Hurkova, K.; Rubert, J.; Stranska-Zachariasova, M.; Hajslova, J. Characterization and Strategies to document adulteration of food supplement based on sea buckthorn oil: a case study. Food Analytical Methods 2016. DOI: 10.1007/s12161-016-0674-4

Hurkova K., Uttl L., Rubert J., Navratilova K., Kocourek V., Stranska- Zachariasova M., Paprstein F., Hajslova J.: Cranberries versus lingonberries: A challenging authentication of similar Vaccinum fruit. Food Chemistry (2019) 284:162-170. (doi: 10.1016/j.foodchem.2019.01.014)

Uttl L., Hurkova K., Kocourek V., Pulkrabova J., Tomaniova M. Hajslova J.: Metabolomics-based authentication of wines according to grape variety. Czech Journal of Food Sciences (2019) 37(4): 239-245. (doi: 10.17221/82/2019-CJFS)

Lacina O., Zachariasova M., Urbanova J., Vaclavikova M., Cajka T., Hajslova J. Critical assessment of extraction methods for the simultaneous determination of pesticide residues and mycotoxins in fruits, cereals, spices and oil seeds employing ultra–high performance liquid chromatography–tandem mass spectrometry. Journal of Chromatography A 2012, 1262, 8 – 18.

Veprikova Z., Vaclavikova M., Lacina O., Dzuman Z., Zachariasova M., Hajslova J. Occurrence of mono- and di-glycosylated conjugates of T-2 and HT-2 toxins in naturally contaminated cereals. World Mycotoxin Journal 2012, 5, 231–240

Agilent 6560 Ion Mobility Q-TOF LC/MS (Agilent Technologies)

Liquid chromatograph Agilent Infinity 1290 coupled with Drift Tube Ion Mobility, Quadrupole Time-of-Flight mass spectrometer and DAD detector (Agilent 6560)

This instrumental system combines the benefits of high-performance liquid chromatography, high-resolution tandem mass spectrometry with a time of flight and quadrupole analyser (Q-TOF), and ion mobility in a drift tube (DTIM) to perform highly efficient three-dimensional ion separation. The mass spectrometer is equipped with the Agilent Jet Stream (AJS) ion source, which provides significantly higher sensitivity compared to traditional electrospray. The instrumentation has a broad application potential for both target and non-target analyses of complex matrices.

Main benefits of the Agilent 6560 Ion Mobility Q-TOF LC/MS system:

Separation of structural isomers - separation of isobaric compounds in ion mobility allows to study their structure and conformation; at the same time it allows to directly measure the collision cross section values without reference standards or calibration curve, providing information about the size of analysed molecules
Increased peak capacity - efficient separation of individual compounds in complex matrices thanks to the combination of UHPLC, ion mobility and high-resolution mass spectrometry
Identification and confirmation of minor components - thanks to the possibility of chemical background elimination in ion mobility and high sensitivity achieved by ion optics, which is ideal for example for the detection of small amounts of contaminants in complex matrices; detection in All Ions MS/MS mode then allows unambiguous identification of analytes
Study of the native structure of proteins - an easy study of the structure of proteins and peptides in the gas phase; the preservation of the native structure is achieved even with labile proteins by minimizing the ion’s energy

◳ Agilent (png) → (originál)

In addition to the above, the system is beyond equipped with an additional non-destructive diode array detector and thus allows to perform the analyses in the LC-DAD-(IM)-Q-TOF setup. At the Department of Food Analysis and Nutrition UCT Prague, this instrumental system is widely used mainly for the analyses within the so-called ‘omics’ disciplines (metabolomics, lipidomics) and for the separation of isomeric compounds which cannot be separated by common chromatographic techniques. The ongoing studies include analysis of lipidome in human blood plasma, analysis of pesticide metabolites, metabolomics profiling of Cannabis bioactive compounds, or study of isomeric forms of mycotoxins and various bioactive substances (e.g. silymarin).

Publications

Fenclova M., Stranska-Zachariasova M., Benes F., Novakova A., Jonatova P., Kren V., Vitek L., Hajslova J.: Liquid chromatography–drift tube ion mobility–mass spectrometry as a new challenging tool for the separation and characterization of silymarin flavonolignans. Analytical and Bioanalytical Chemistry (2020) 412(4): 819-832. (doi: 10.1007/s00216-019-02274-3)

Viktorova J., Stranska-Zachariasova M., Fenclova M., Vitek L., Hajslova J., Kren V., Ruml T.: Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements. Antioxidants (2019) 8(8): 317. (doi: 10.3390/antiox8080317)

Bechynska K., Daskova N., Vrzackova N., Harant K., Heczkova M., Podzimkova K., Bratova M., Dankova H., Berkova Z., Kosek V., Zelenka J., Hajslova J., Sedlacek R., Suttnar J., Hlavackova A., Bartonova L., Cahova M.: The effect of ω-3 polyunsaturated fatty acids on the liver lipidome, proteome and bile acid profile: parenteral versus enteral administration. Scientific Reports (2019) 9: 19097. (doi: 10.1038/s41598-019-54225-8)

Schusterova D., Suchanova M., Pulkrabova J., Kocourek V., Urban J., Hajslova J.: Can occurrence of pesticide metabolites detected in crops provide the evidence on illegal practices in organic farming? Journal of Agricultural and Food Chemistry (2019) 67(22): 6102-6115. (doi: 10.1021/acs.jafc.8b06999)

Righetti L., Fenclova M., Dellafiora L., Hajslova J., Stranska-Zachariasova M., Dall’Asta C.: High resolution-ion mobility mass spectrometry as an additional powerful tool for structural characterization of mycotoxin metabolites. Food Chemistry (2018) 245: 768-774. (doi: 10.1016/j.foodchem.2017.11.113)

AutoPure prep LC – LCT Premier XE (Waters)

Preparative liquid chromatograph Waters AutoPurification System coupled with high-resolution mass spectrometer Waters LCT Premier XE

Preparative chromatography is used to purify and isolate biologically active compounds (or groups of compounds) from extracts of various matrices for their further study. The chromatographic system consists of the following parts; (i) a quaternary gradient pump (Waters 2545 Quaternary Gradient Module), (ii) a system fluidics organizer (SFO) allowing automatic switching between analytical and preparative separation mode with up to three analytical and two preparative columns, (iii) flow splitter (8-30 ml, 1000: 1), (iv) 515 make-up pump, (v) sample injector/fraction collector (Waters 2767 Sample Manager) for analytical/preparative operation mode, with separate fluid paths for injection and collection of sample fractions. Thanks to the connection with a high-resolution mass spectrometer with TOF analyser (Waters LCT Premier XE), it is possible to collect fractions not only depending on the elution time of analytes but especially selectively based on a defined exact mass (m/z) of ions of the compounds of interest. The system is equipped with an electrospray as an ionization source. Thanks to its robustness and flexible configuration, the system is suitable for purification of material in the order of milligrams to several grams while the high purity and yield of isolated compounds are maintained.

At the Department of Food Analysis and Nutrition UCT Prague, this instrumental system is used for isolation of glycosylated mycotoxins, or fractionation of extracts of various plant materials for chemical characterization purposes and further study of biological activities of individual obtained fractions.

Agilent 6495 Triple Quadrupole LC/MS (Agilent Technologies)

Liquid chromatograph Agilent 1290 Infinity II coupled with tandem mass spectrometer Agilent Triple Quadrupole 6495

This instrument is due to its sensitivity and selectivity suitable for the routine analysis of the broad range of biologically active compounds. It is used for analyses of environmental contaminants (e.g. per- and polyfluoroalkylated substances and brominated flame retardants within the human biomonitoring studies), phytocannabinoids and pesticide residues. Also, the analyses of the other significant groups of contaminants, e.g. bisphenols and organophosphate flame retardants in various types of environmental samples are performed on this instrument. The triple quadrupole mass spectrometer works based on the principle of monitoring the specific transitions between precursor and product ions of the target compounds. The ionization of analytes is performed by electrospray ionization technique.

Application examples

• Analysis of perfluoroalkylated substances, brominated and organophosphate flame retardants in water, food, biological and environmental samples
• Analysis of bisphenol A and its derivates in biological samples
• Analysis of pesticide residues in water, fruits, vegetables, teas, and cereals
• Analysis of phytocannabinoids and their metabolites in biological samples
• Analysis of plant alkaloids in spices, teas, cereals, and pseudo cereals
• Analysis of migrants from food packaging

Agilent 6495C Triple Quadrupole LC/MS (Agilent Technologies)

Liquid chromatograph Agilent 1290 Infinity II coupled with tandem mass spectrometer Agilent Triple Quadrupole 6495C

This instrumental system combines the advantages of ultra-performance liquid chromatography and tandem mass spectrometry consisting of a new generation MS system A6495C (triple quadrupole analyser). The instrumentation is especially used for trace analyses, such as analysis of food contaminants, where the very low detection limits (up to 0.001 mg/kg) need to be achieved. The 3rd generation of this detector type provides sufficient mass resolution up to 3000 m/z. For the multiresidual analyses, the dMRM acquisition mode is used, allowing to monitor specific transitions between the precursor and product ions for high number of substances in a certain time interval while maintaining sufficient sensitivity and selectivity. This instrumentation is mainly used for analysis of pesticide residues in a large variety of food commodities, providing the detection and confirmation of up to 400 different compounds within a short period of time. The application scope includes fast screening of the substances present in the sample, as well as their confirmation and very fast quantification using Agilent MassHunter software. For the ionization of analytes, the electrospray technique is used. The Vent-free ion source equipped with the VacSchield system enables to maintain a vacuum in the MS system during service.

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Direct Analysis in Real Time (DART) connected to 5600 TripleTOF (SCIEX) or Exactive (Thermo Fisher Scientific) or AccuTOF MS system (JEOL)
Atmospheric Solids Analysis Probe (ASAP) (Waters) SYNAPT G2 HDMS (Waters)

Publikace / Publications

2024

1.	Fuente-Ballesteros A., Brabenec O., Tsagkaris A.S., Ares A.M., Hajslova J., Bernal J.: Comprehensive overview of the analytical methods for determining pyrrolizidine alkaloids and their derived oxides in foods. Journal of Food Composition and Analysis (2024), 125:105758. (doi:10.1016/j.jfca.2023.105758)
2.	Kokalj A.J., Kolcikova G., Selonen S., Bosker T., Drobne D., Dvorakova D., Hofman J., Hurley R., Kernchen S., Laforsch Ch., Loder M.G.J., van Loon S., Redondo-Hasselerharm P.E.R., Saartama V., Smidova K., Tsagkaris A.S., Zantis L.J., Nizzetto L., van Gestel C.A.M.: Strategy towards producing relevant and reliable data for the hazard assessment of micro- and nanoplastics in agricultural soils. Trend in Analytical Chemistry (2024) 172:117567. (doi: 10.1016/j.trac.2024.117567)
3.	Kucerka O., Blahutova M., Kosek V., Minarikova P., Horacek J.M., Urbanek P., Maly M.: Exploring the Role of GDF-15 in Inflammatory Bowel Disease: A Case-Controlled Study Comparing Crohn’s Disease and Ulcerative Colitis with Non-Inflammatory Controls. Metabolites (2024) 14(4) 185. (doi: 10.3390/metabo14040185)
4.	Parizek O., Zavodna T., Milcova A., Drabova L., Stupak M., Gomersall V., Schmuczerova J., Jirik V., Topinka J., Pulkrabova J.: Personal exposure monitoring to polycyclic aromatic hydrocarbons bound to size-segregated aerosol. Atmospheric Pollution Research (2024) in press, 102122. (doi: 10.1016/j.apr.2024.102122)
5.	Schusterova D., Horska T., Skalsky M., Stara J., Ourednickova J., Uttl L., Kocourek V., Hajslova J.: Three-year monitoring study of pesticide dissipation in pears. Journal of Food Composition and Analysis (2024) 126:105863. (doi: 10.1016/j.jfca.2023.105863)
6.	Skvorova P., Kulma M., Bozik M., Kurecka M., Plachy V., Slavikova D., Sebelova K., Kourimska L.: Evaluation of rapeseed cake as a protein substitute in the feed of edible crickets: A case study using Gryllus assimilis. Food Chemistry (2024) 441: 138254. (doi: 10.1016/j.foodchem.2023.138254)
7.	Tittlemier S.A., Cramer B., DeRosa M.C., Dzuman Z., Malone R., Maragos C., Suma M., Sumarah M.W.: Developments in analytical techniques for mycotoxin determination: an update for 2022-23. World Mycotoxin Journal (2024) accepted (doi: 10.1163/18750796-bja10002)
8.	Wojciechowicz-Budzisz A., Skřivan P., Sluková M., Švec I., Pejcz E., Stupák M., Czubaszek A., Harasym J.: Comprehensive Characterization of Micronized Wholemeal Flours: Investigating Technological Properties across Various Grains. Foods (2024) 13(1): 39. (doi: 10.3390/foods13010039)

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Publikace / Publications

2023

1.	Ahmed B., Benes F., Hajslova J., Fisarova L., Vosatka M., Hijri M.: Enhanced production of select phytocannabinoids in medical Cannabis cultivars using microbial consortia. FRONTIERS IN PLANT SCIENCE (2023) 14: 1219836. (doi: 10.3389/fpls.2023.1219836)
2.	Behnisch P., Petrlik J., Budin C., Besselink H., Felzel E., Strakova J., Bell L., Kuepouo G., Gharbi S., Bejarano F., Jensen G.K., DiGangi J., Ismawati Y., Speranskaya O., Da M., Pulkrabova J., Gramblicka T., Brabcova K., Brower A.: Global survey of dioxin- and thyroid hormone-like activities in consumer products and toys. Environment International (2023) 178: 108079. (doi: 10.1016/j.envint.2023.108079)
3.	Bušová M., Kouřimská L., Doležal M., Ilko V., Revenco D., Zare M., Matoušek J., Ferrocino I., Franciosa I., Smejkal P., Přeslička M., Prokešová M.: Fatty Acid Profile, Atherogenic and Thrombogenic Indices, and Meat Quality as the Effect of Feed Additive in African Catfish Clarias gariepinus (Burchell, 1822). Applied Sciences (2023) 18(13): 10058. (doi: 10.3390/app131810058)
4.	Ciglova K., Vondraskova V., Milcova A., Rossnerova A., Sram R.J., Topinka J., Pulkrabova J.: A Simultaneous Determination of Benzophenone and Camphor UV-Filters, Together with Metabolites of Polycyclic Aromatic Hydrocarbons, in Human Urine. Exposure and Health (2023) on-line. (doi: 10.1007/s12403-023-00554-z)
5.	Cipryan L., Kosek V., Carlos J. Garcia Hernandez, Dostal T., Bechynska K., Hajslova J., Hofmann P.: A lipidomic and metabolomic signature of a very low-carbohydrate high-fat diet and high-intensity interval training: an additional analysis of a randomized controlled clinical trial. Metabolomics (2023) 20(1)10. (doi: 10.1007/s11306-023-02071-1)
6.	Dvorakova D., Jurikova M., Svobodova V., Parizek O., Kozisek F., Kotal F., Jeligova H., Mayerova L., Pulkrabova J.: Complex monitoring of perfluoroalkyl substances (PFAS) from tap drinking water in the Czech Republic. Water Research (2023) 247: 120764. (doi: 10.1016/j.watres.2023.120764)
7.	Drabova L, Pulkrabova J., Hrbek V., Kocourek V., Hajslova J.: POPs and PAHs in fish oil-based food supplements at the Czech market. FOOD ADDITIVES & CONTAMINANTS: PART B (2023) 16(3): 2200374. (doi: 10.1080/19393210.2023.2200374)
8.	Ehlers M., Uttl L., Riedl J., Raeke J., Westkamp I., Hajslova J., Brockmeyer J., Fauhl-Hassek C.: Instrument comparability of non-targeted UHPLC-HRMS for wine authentication. Food Control (2023) 144:109360. (doi: 10.1016/j.foodcont.2022.109360)
9.	Filatova M., Hajslova J., Stupak M.: Detection of saffron adulteration by other plant species using SPME-GC-HRMS . European Food Research and Technology (2023) published. (doi: 10.1007/s00217-023-04443-2)
10.	Govarts E., Gilles L., Martin L.R., .....Dvorakova D., .....Schoeters G.: Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014–2021). International Journal of Hygiene and Environmental Health (2023) 249: 114119. (doi: 10.1016/j.ijheh.2023.114119)
11.	Gramblicka T., Parizek O., Stupak M., Pulkrabova J.: Assessment of atmospheric pollution by oxygenated and nitrated derivatives of polycyclic aromatic hydrocarbons in two regions of the Czech Republic. Atmospheric Environment (2023) 310: 119981. (doi: 10.1016/j.atmosenv.2023.119981)
12.	Gregorová E., Nakonechna K., Ilko V., Zlatohlávek L., Doležal M.: Nutriční a senzorická hodnota alternativ masa. Výživa a potraviny (2023) 4(8): 6-9.
13.	Ilko V., Sosnová D., Hrůšová P., Fišnar J., Czornyj Š., Doležal M., Nakonechna K., Réblová Z.: Loss of Vitamin E While Baking and Heating French Fries. Applied Sciences (2023) 13(21). (doi: 10.3390/app132111965)
14.	Krizkovska B., Hoang L., Brdova D., Klementova K., Szemeredi N., Louckova A., Kronusova O., Spengler G., Kastanek P., Hajslova J., Viktorova J., Lipov J.: Modulation of the bacterial virulence and resistance by well-known European medicinal herbs. Journal of Ethnopharmacology (2023) 312:116484. (doi: 10.1016/j.jep.2023.116484)
15.	Kulisova M., Matatkova O., Branyik T., Zelenka J., Drabova L. , Kolouchova I. J.: Detection of microscopic filamentous fungal biofilms – Choosing the suitable methodology. Journal of Microbiological Methods (2023) 205:106676. (doi: 10.1016/j.mimet.2023.106676)
16.	Maly M., Benes F., Binova Z., Zlechovcova M., Kastanek P., Hajslova J.: Effective isolation of cannabidiol and cannabidiolic acid free of psychotropic phytocannabinoids from hemp extract by fast centrifugal partition chromatography. Analytical and Bioanalytical Chemistry (2023) SI 415(19): 4827-4837. (doi: 10.1007/s00216-023-04782-9)
17.	Merino I., Olarte Guasca A., Krmela A., Arif U., Ali A., Westerberg E., Kashinath Jalmi S., Hajslova J., Schulzova V., Sitbon F.: Metabolomic and Transcriptomic Analyses Identify External Conditions and Key Genes Underlying High Levels of Toxic Glycoalkaloids in Tubers of Stress-sensitive Potato Cultivars. Frontiers in Plant Science (2023), 14:1210850. (doi: 10.3389/fpls.2023.1210850)
18.	Nelis J.L.D., Schacht V.J., Dawson A.L., Bose U., Tsagkaris A.S., Dvorakova D., Beale D.J., Can A., Elliot Ch.T., Thomas V.T., Broadbent J.A.: The measurement of food safety and security risks associated with micro- and nanoplastic pollution. Trends in Analytical Chemistry (2023) 161: 116993. (doi: 10.1016/j.trac.2023.116993)
19.	Novotna T., Sitarova B, Hoskova Z., Vaibarova V., Dzuman Z., hajslova J., Skupien V., Svobodova Z.: Tremorgenic mycotoxin poisoning in a dog: A case report. Veterinarni medicina (2023) 68(12): 483-489. (doi: 10.17221/82/2023-VETMED)
20.	Nübler S., Lopez M.E., Castano A., Mol H.G.J., Müller J., Schäfer M., Haji-Abbas-Zarrabi K., Hajslova J., Pulkrabova J., Dvorakova D., Urbancova K., Koch H.M., Antignac J-P., Sakhi A.K., Vorkamp K., Burkhardt T., Scherer M., Göen T.: External Quality Assurance Schemes (EQUASs) and Inter-laboratory Comparison Investigations (ICIs) for human biomonitoring of polycyclic aromatic hydrocarbon (PAH) biomarkers in urine as part of the quality assurance programme under HBM4EU. International Journal of Hygiene and Environmental Health (2023) 250: 114169. (doi: 10.1016/j.ijheh.2023.114169)
21.	Book “Smartphones for Chemical Analysis: From Proof-of-concept to Analytical Applications” edited by J.L.D. Nelis and A.S. Tsagkaris, Comprehensive Analytical Chemistry, Vol. 101, 2023, Elsevier, ISBN 978-0-443-13405-0
22.	Paluch Z., Biriczova L., Pallag G., Chrbolka P., Vargova N., Marques E., Alusik S., Hercogova J., Hurkova K., Hajslova J.: Agrimonia eupatoria L. and wound healing. Journal of Herbal Medicine (2023) 42: 100765. (doi: 10.1016/j.hermed.2023.100765)
23.	Parizek O., Gramblicka T., Parizkova D., Polachova A., Bechynska K., Dvorakova D., Stupak M., Dusek J., Pavlikova J., Topinka J., Sram R.J., Pulkrabova J.: Assessment of organohalogenated pollutants in breast milk from the Czech Republic. Science of the Total Environment (2023) 871: 161938 (doi: 10.1016/j.scitotenv.2023.161938)
24.	Prusova N., Behner A., Dzuman Z., Hajslova J., Stranska M.: Conjugated type a trichothecenes in oat-based products: Occurrence data and estimation of the related risk. Food Control (2023) 143: 109281. (doi: 10.1016/j.foodcont.2022.109281)
25.	Purwidyantri A., Azinheiro S., Roldan A.G., Jaegerova T., Vilaca A., Machado R., Cerqueira M.F., Borme J., Domingues T., Martins M., Alpuim P., Prado M.: Integrated approach from sample-to-answer for grapevine varietal identification on a portable graphene sensor chip. ACS Sensors (2023) 8(2): 640–654. (doi: 10.1021/acssensors.2c02090)
26.	Rempelos L., Baranski M., Sufar E.K., Gilroy J., Shotton P., Leifert H., Srednicka-Tober D., Hasanaliyeva G., Rosa E.A.S., Hajslova J., Schulzova V., Cakmak I., Ozturk L., Brandt K., Seal Ch., Wang J., Schmidt Ch., Leifert C.: Effect of Climatic Conditions, and Agronomic Practices Used in Organic and Conventional Crop Production on Yield and Nutritional Composition Parameters in Potato, Cabbage, Lettuce and Onion; Results from the Long-Term NFSC-Trials. Agronomy-Basel (2023) 13(5): 1225. (doi: 10.3390/agronomy13051225)
27.	Ryparova Kvirencova J., Navratilova K., Hrbek V., Hajslova J.: Detection of botanical adulterants in saffron powder. Analytical and Bioanalytical Chemistry (2023) 415(23):5723-5734. (doi: 10.1007/s00216-023-04853-x)
28.	Samolada S., Vasilopoulou D.G., Danezis G.PP., Tsagkaris A.S.: Confirming smartphone-based assay results using instrumental analysis in the book “Smartphones for Chemical Analysis: From Proof-of-concept to Analytical Applications” edited by J.L.D. Nelis and A.S. Tsagkaris, Comprehensive Analytical Chemistry Vol. 101, pp 277-295, 2023, Elsevier, ISBN 978-0-443-13405-0. (doi: 10.1016/bs.coac.2023.03.001)
29.	Sevenich R., Gratz M., Hradecka B., Fauster T., Teufl T., Schottroff F., Souckova Chytilova L., Hurkova K., Tomaniova M., Hajslova J., Rauh C., Jaeger H.: Differentiation of sea buckthorn syrups processed by high pressure, pulsed electric fields, ohmic heating and thermal pasteurization based on quality evaluation and chemical fingerprinting. Frontiers in Nutrition (2023) 10:156. (doi: 10.3389/fnut.2023.912824)
30.	Schusterova D., Mráz P., Uttl L., Drábová L., Kocourek V., Hajslova J.: Pesticide residues in fresh and processed edible mushrooms from Czech markets. Food Additives & Contaminants: Part B (2023) 16(4): 384-392. (doi: 10.1080/19393210.2023.2259867)
31.	Smid V., Dvorak K., Stehnova K., Strnad H., Rubert J., Stříteský J., Staňková B., Stránská M., Hajšlová J., Brůha R., Vítek L.: The Ameliorating Effects of n-3 Polyunsaturated Fatty Acids on Liver Steatosis Induced by a High-Fat Methionine Choline-Deficient Diet in Mice. International Journals of Molecular Sciences (2023) 24(24): 17226. (doi: 10.3390/ijms242417226)
32.	Stelzl T., Belc N., Cito N., Lattanzio V.M.T., Meerpoel C., De Saeger S., Alakomi H.-L., Tomaniova M., Hajslova J., Scheibenzuber S., Rychlik M.: European food safety research: An explorative study with funding experts’ consultation. Heliyon (2023) 9(12): e22979. (doi: 10.1016/j.heliyon.2023.e22979)
33.	Stranska M., Prusova N., Behner A., Dzuman Z., Lazarek M., Tobolkova A., Chrpova J., Hajslova J.: Influence of pulsed electric field treatment on the fate of Fusarium and Alternaria mycotoxins present in malting barley. Food Control (2023) 145: 109440. (doi: 10.1016/j.foodcont.2022.109440)
34.	Tittlemier S.A., Cramer B., DeRosa M.C., Lattanzio V.M.T., Malone R., Maragos C., Stranska M., Sumarah M.W.: Developments in mycotoxin analysis: an update for 2021-22. World Mycotoxin Journal (2023). 16 (1): 3-24. (doi: 10.3920/WMJ2022.2822)
35.	Tomasko J., Parizek O., Pulkrabova J.: Short- and medium-chain chlorinated paraffins in T-shirts and socks. Environmental Pollution (2023) 333:122065. (doi: 10.1016/j.envpol.2023.122065)
36.	Tsagkaris A.S., Bechynska K., NtakoulasD.D., Pasias I.N., Weller P., Proestos C., Hajslova J.: Investigating the impact of spectral data pre-processing to assess honey botanical origin through Fourier transform infrared spectroscopy (FTIR). Journal of Food Composition and Analysis (2023), 119: 105276. (doi: 10.1016/j.jfca.2023.105276)
37.	Tsagkaris A.S., Louckova A., Polak J., Hajslova J.: Identifying edible plants with high anti-obesity potential: In vitro inhibitory effect against pancreatic lipase followed by bioactive compound metabolomic screening. Food Bioscience (2023), Vol. 56, 103453. (doi: 10.1016/j.fbio.2023.103453)
38.	Tsagkaris A. S., Nelis J. L. D., Campbell K., Elliott C. T., Pulkrabova J., Hajslova J.: Chapter 8 - Smartphone and microfluidic systems in medical and food analysis, in the book "Microfluidic Biosensors" edited by W. C. Mak & - A. Ho Pui Ho, 2023, Elsevier, ISBN: 978-0-12-823846-2 (doi: 10.1016/B978-0-12-823846-2.00002-X)
39.	Uttl L., Bechynska K., Ehlers M., Kadlece V., Navratilova K., Dzuman Z., Fauhl-Hassek C., Hajslova J.: Critical assessment of chemometric models employed for varietal authentication of wine based on UHPLC-HRMS data. Food Control (2023) 143: 109336. (doi: 10.1016/j.foodcont.2022.109336)
40.	Vrublevskaya M., Nguyenova T.T.M., Drabova L., Lovecka P., Vrchotova B., Matatkova O., Kulisova M., Kolouchova I.J.: Biodiversity of Vitis vinifera endophytes in conventional and biodynamic vineyard. Czech Journal of Food Sciences (2023) 41(1):44-53. (doi: 10.17221/200/2022-CJFS)

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Publikace / Publications

2022

1.	Ambroz A., Rossner Pavel Jr., Rossnerova A., Honkova K., Milcova A., Pastorkova A., Klema J., Pulkrabova J., Parizek O., Vondraskova V., Zelenka J., Vrzackova N., Schmuczerova J., Topinka J., Sram R.J.: Oxidative Stress and Antioxidant Response in Populations of the Czech Republic Exposed to Various Levels of Environmental Pollutants. Environmental Research and Public Health (2022). 19, 3609. (doi: 10.3390/ijerph19063609)
2.	Drabova L., Dvorakova D., Urbancova K., Gramblicka T., Hajslova J., Pulkrabova J.: Critical Assessment of Clean-Up Techniques Employed in Simultaneous Analysis of Persistent Organic Pollutants and Polycyclic Aromatic Hydrocarbons in Fatty Samples. Toxics (2022), 10 (1),12. (doi: 10.3390/toxics10010012)
3.	Drabova L., Libenska L., Zednikova M., Vondraskova V., Hajslova J., Pulkrabova J.: Analysis of UV-Treated Mushrooms: Dietary Source of Vitamin D2 ? LC-GC (2022) 35(s7):35-38. (pdf)
4.	Dragoun M., Klausova K., Simicova P., Honzikova T., Stejskal J., Navratilova K., Hajslova J., Barta J., Bartova V., Jarosova M., Bjelkova M., Filip V.: Formation of Previously Undescribed Δ⁷-Phytosterol Oxidation Products and Tocopherylquinone Adducts in Pumpkin Seed Oil during Roasting, Screw-Pressing, and Simulated Culinary Processing at Elevated Temperatures. Journal of Agricultural and Food Chemistry (2022) 70(37): 11689 - 11703. (doi: 10.1021/acs.jafc.2c03292)
5.	Filatova M., Bechynska K., Hajslova J., Stupak M.: A comprehensive characterization of volatile profiles of plum brandies using gas chromatography coupled to high resolution mass spectrometry. LWT (2022), 167, 113864. (doi: 10.1016/j.lwt.2022.113864)
6.	Fiserova I., Trinh M.D., Elkalaf M., Vacek L., Heide M., Martinkova S., Bechynska K., Kosek V., Hajslova J., Fiser O., Tousek P., Polak J.: Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes: In vitro model of takotsubo syndrome. Frontiers in Cardiovascular Medicine (2022) 9:917989. (doi: 10.3389/fcvm.2022.917989)
7.	Fisnar J., Reblova Z.: Vitamin E – Known or Unknown? Chemicke listy (2022) 116(5): 287 - 292. (doi: 10.54779/chl20220287)
8.	Garcia C.J., Kosek V., Beltran D., Tomas-Barberan F.A., Hajslova J.: Production of New Microbially Conjugated Bile Acids by Human Gut Microbiota. Biomolecules (2022) 12(5): 687. (doi: 10.3390/biom12050687)
9.	Jurikova M., Dvorakova D., Pulkrabova J.: The occurrence of perfluoroalkyl substances (PFAS) in drinking water in the Czech Republic: a pilot study. Environmental Science and Pollution Research (2022) 29, 60341–603. (doi: 10.1007/s11356-022-20156-7)
10.	Kosek V., Hajsl M., Bechynska K., Kucerka O., Suttnar J., Hlavackova A., Hajslova J., Maly M.: Long-Term Effects on the Lipidome of Acute Coronary Syndrome Patients. Metabolites (2022) 12(2): 124. (doi: 10.3390/metabo12020124)
11.	Kouba V., Hurkova K., Navratilova K., Kok D., Benakova A., Laureni M., Vodickova P., Podzimek T., Lipovova P., van Niftrik L., Hajslova J., van Loosdrecht M.C.M., Weissbrodt D.G., Bartacek J.: Effect of temperature on the compositions of ladderane lipids in globally surveyed anammox populations. Science of the Total Environment (2022) 830: 154715. (doi: 10.1016/j.scitotenv.2022.154715)
12.	Kouba V., Hurkova K., Navratilova K., Kok D., Benakova A., Laureni M., Vodickova P., Podzimek T., Lipovova P., van Niftrik L., Hajslova J., van Loosdrecht M.C.M., Weissbrodt D.G., Bartacek J.: On anammox activity at low temperature: Effect of ladderane composition and process conditions. Chemical Engineering Journal (2022) 445:136712. (doi: 10.1016/j.cej.2022.136712)
13.	Kouba V., Vejmelkova D., Zwolsman E., Hurkova K., Navratilova K., Laureni M., Vodickova P., Podzimek T., Hajslova J., Pabst M., van Loosdrecht M.C.M., Bartacek J., Lipovova P., Weissbrodt D.G.: Adaptation of anammox bacteria to low temperature via gradual acclimation and cold shocks: Distinctions in protein expression, membrane composition and activities. Water Research (2022) 209,117822. (doi: 10.1016/j.watres.2021.117822)
14.	G.A.Koulis, A.S. Tsagkaris, P.A. Katsianou, P.P. Gialouris, I.Martakos, F. Stergiou, A. Fiore, E. I. Panagopoulou, S. Karabournioti,C. Baessmann, N. van der Borg, M.E. Dasenaki, C.Proestos and N.S. Thomaidis, Thorough Investigation of the Phenolic Profile of Reputable Greek Honey Varieties: Varietal Discrimination and Floral Markers Identification Using Liquid Chromatography–High-Resolution Mass Spectrometry, Molecules 2022, 27(14), 4444. (doi: 10.3390/molecules27144444)
15.	Kourimsky T., Hrbek V., Steidl M., Hajslova J.: Analysis of MCPD and Glycidyl Fatty Acid Esters in Refined Plant Oils by Supercritical Fluid ChromatographyHigh-Resolution Mass Spectrometry. LC-GC (2022) 35(s7):28-34. (pdf)
16.	Kvirencova J., Hrbek V., Tomaniova M., Hajslova J.: Authentication of Panax Ginseng‑Based Herbal Teas Using “Chemical Markers” Strategy. LC-GC (2022) 35(s7):20-24. (pdf)
17.	Mol H.G.J., Elbers I., Pälmke C., Bury D., Göen T., Lopez M.E., Nübler S., Vaccher V., Antignac J.-P., Dvorakova D., Hajslova J., Sakhi A.K., Thomsen C., Vorkamp K., Castaño A., Koch H.M.: Proficiency and Interlaboratory Variability in the Determination of Phthalate and DINCH Biomarkers in Human Urine: Results from the HBM4EU Project. Toxics (2022), 10, 57. (doi: 10.3390/toxics10020057)
18.	Navratilova K., Hurkova K., Hrbek V., Uttl L., Tomaniova M., Valli E., Hajslova J.: Metabolic fingerprinting strategy: Investigation of markers for the detection of extra virgin olive oil adulteration with soft-deodorized olive oils. Food Control (2022) 134,108649. (doi: 10.1016/j.foodcont.2021.108649)
19.	Nelis J.L. D. , Rosas da Silva G., Ortuño J., Tsagkaris A. S., Borremans B., Hajslova J., Colgrave M. L., Elliott C. T.: The General Growth Tendency: A tool to improve publication trend reporting by removing record inflation bias and enabling quantitative trend analysis. PLoS ONE (2022) 17(5): e0268433. (doi: 10.1371/journal.pone.0268433)
20.	Nübler S., Lopez M. E., Castano A., Mol H. G. J., Haji-Abbas-Zarrabi K., Schäfer M., Hajslova J., Dvorakova D., Antignac J.-P., Koch H. M., Huag L. S., Vorkamp K., Göen T.: Interlaboratory Comparison Investigations (ICIs) and External Quality Assurance Schemes (EQUASs) for human biomonitoring of perfluoroalkyl substances (PFASs) in serum as part of the quality assurance programme under HBM4EU. Science of The Total Environment (2022) 847: 157481 (doi: 10.1016/j.scitotenv.2022.157481)
21.	Nübler S., Schäfer M., Haji-Abbas-Zarrabi K., Markovic S., Markovic K., Lopez M.E., Castano A., Mol H., Koch H. M., Antignac J.-P., Hajslova J., Thomsen C., Vorkamp K., Göen T.: Interlaboratory Comparison Investigations (ICIs) for human biomonitoring of chromium as part of the quality assurance programme under HBM4EU. Journal of Trace Elements in Medicine and Biology (2022) 70: 126912. (doi: 10.1016/j.jtemb.2021.126912)
22.	Pavlikova J., Ambroz A., Honkova K., Chvojkova I., Sram R.J., Rossner P. Jr., Topinka J., Gramblicka T., Parizek O., Parizkova D., Schmuczerova J., Pulkrabova J., Rossnerova A.: Maternal Diet Quality and the Health Status of Newborns. Foods (2022) 11(23): 3893. (doi: 10.3390/foods11233893)
23.	Pohorela B., Gramblicka T., Dolezal M., Dvorakova D., Pulkrabova J., Kourimska L., Ilko V., Panek J.: Nutritional Quality and Assessment of Contaminants in Farmed Atlantic Salmon (Salmo salar L.) of Different Origins. Journal of Food Quality (2022) 2022: 9318889 (doi: 10.1155/2022/9318889)
24.	Pohorela B., Polachova A., Ruzickova M., Dolezal M., Pulkrabova J., Panek J.: Nutritional evaluation of the full-day diet. Czech Journal of Food Sciences (2022) 40: 118–129 (doi: 10.17221/273/2021-CJFS)
25.	Prusova N., Dzuman Z., Jelinek L., Karabin M., Hajslova J., Rychlik M., Stranska M.: Free and conjugated Alternaria and Fusarium mycotoxins during Pilsner malt production and double-mash brewing. Food Chemistry (2022), 369: 130926. (doi: 10.1016/j.foodchem.2021.130926)
26.	Reblova Z., Aubourg S.P., Pokorny J.: The Effect of Different Freshness of Raw Material on Lipid Quality and Sensory Acceptance of Canned Sardines. Foods (2022) 11(13): 1987. (doi: 10.3390/foods11131987)
27.	Rektorisova M., Hrbek V., Tomaniova M., Cuhra P., Hajslova J.: Supercritical fluid chromatography coupled to high-resolution tandem mass spectrometry: an innovative one-run method for the comprehensive assessment of chocolate quality and authenticity. Analytical and Bioanalytical Chemistry (2022) 414: 6825–6840. (doi: 10.1007/s00216-022-04246-6)
28.	Rektorisova M., Tomaniova M., Hajslova J.: Nut and seed butters: lipid component quality and its changes during storage. European Food Research and Technology (2022) 248: 2531–2538. (doi: 10.1007/s00217-022-04067-y)
29.	Schulzova V., Koudela M., Chmelarova H., Hajslova J., Novotny C.: Assessment of Carrot Production System Using Biologically Active Compounds and Metabolomic Fingerprints. Agronomy (2022) 12(8): 1770. (doi: 10.3390/agronomy12081770)
30.	Smid V., Dvorak K., Sedivy P., Kosek V., Lenicek M., Dezortova M., Hajslova J., Hajek M., Vitek L., Bechynska K., Bruha R.: Effect of Omega-3 Polyunsaturated Fatty Acids on Lipid Metabolism in Patients With Metabolic Syndrome and NAFLD. Hepatology Communications (2022) 6(6): 1336-1349. (doi: 10.1002/hep4.1906)
31.	Steiner D., Humpel A., Stamminger E., Schoeberl A., Pachschwoell G., Sloboda A., Swoboda Ch., Rigg J., Zhang D., Greer B., Elliott Ch. T., Dzuman Z., Hajslova J., Gschaider A., Fechner C., Forstner L., Varga El, Jedziniak P., Pietruszka K., Rudawska A., Malachova A.: An Interlaboratory Comparison Study of Regulated and Emerging Mycotoxins Using Liquid Chromatography Mass Spectrometry: Challenges and Future Directions of Routine Multi-Mycotoxin Analysis including Emerging Mycotoxins. Toxins (2022) 14(6), 405. (doi: 10.3390/toxins14060405)
32.	Stranska M., Dzuman Z., Prusova N., Behner A., Kolouchova I., Lovecka P., Rezanka T., Kolarik M., Hajslova J.: Fungal Endophytes of Vitis vinifera-Plant Growth Promoters or Potentially Toxinogenic Agents? Toxins (2022) 14(2): 66. (doi: 10.3390/toxins14020066)
33.	Tittlemier S.A., Cramer B., Dall´Asta C., DeRosa M.C., Lattanzio V.M.T., Malone R., Maragos C., Stranska M., Sumarah M.W.: Developments in mycotoxin analysis: An update for 2020-2021. World Mycotoxins Journal (2022) 15(1): 3-25. (doi: 10.3920/WMJ2021.2752)
34.	Timkina E, Drabova L, Palyzova A, Rezanka T, Matatkova O, Kolouchova I.: Kocuria Strains from Unique Radon Spring Water from Jachymov Spa. Fermentation (2022) 8 (1),35. (doi: 10.3390/fermentation8010035)
35.	Tomasko J., Hrbek V., Kourimsky T., Stupak M., Hajslova J., Pulkrabova J.: Are fish oil-based dietary supplements a significant source of exposure to chlorinated paraffins? Science of the Total Environment (2022) 833, 155137. (doi: 10.1016/j.scitotenv.2022.155137)
36.	Tomasko J., Maxa D., Navratilova K., Kourimsky T., Hrbek V., Hajslova J., Pulkrabova J.: Application of Liquid- and Supercritical Fluid Chromatography Coupled with High-Resolution Mass Spectrometry for the Analysis of Short-, Medium-, and Long-Chain Chlorinated Paraffins in Dietary Supplements. LC-GC (2022) 35(s7):7-11. (pdf)
37.	Tsagkaris A.S., Hrbek V., Dzuman Z., Hajslova J.: Critical comparison of direct analysis in real time orbitrap mass spectrometry (DART-Orbitrap MS) towards liquid chromatography mass spectrometry (LC-MS) for mycotoxin detection in cereal matrices. Food Control 2022, 132: 108548. (doi: 10.1016/j.foodcont.2021.108548)
38.	Tsagkaris A.S., Kalogiouri N., Hrbek V., Hajslova J.: Spelt authenticity assessment using a rapid and simple Fourier transform infrared spectroscopy (FTIR) method combined to advanced chemometrics. European Food Research and Technology (2022) 249: 441-450. (doi: 10.1007/s00217-022-04128-2)
39.	Tsagkaris A. S., Louckova A., Jaegerova T., Tokarova V., HajslovaJ.: The In Vitro Inhibitory Effect of Selected Asteraceae Plants on Pancreatic Lipase Followed by Phenolic Content Identification through Liquid Chromatography High Resolution Mass Spectrometry (LC-HRMS). International Journal of Molecular Sciences (2022) 23(19): 11204 (doi: 10.3390/ijms231911204)
40.	Tsagkaris A.S., Uttl L., Dzuman Z., Pulkrabova J., Hajslova J.: A critical comparison between an ultra-high-performance liquid chromatography triple quadrupole mass spectrometry (UHPLC-QqQ-MS) method and an enzyme assay for anti-cholinesterase pesticide residue detection in cereal matrices. Analytical Methods (2022), 14, 1479-1489. (doi: 10.1039/d2ay00355d )
41.	Vaccher V., Lopez M.E., Castano A., Mol H., Haji-Abbas-Zarrabi K., Bury D., Koch H.M., Dvorakova D., Hajslova J., Nübler S., Sakhi A.K., Thomsen C., Vorkamp K., Göen T., Antignas J.-P.: European interlaboratory comparison investigations (ICI) and external quality assurance schemes (EQUAS) for the analysis of bisphenol A, S and F in human urine: Results from the HBM4EU project. Environmental Research (2022) 210, 112933. (doi:10.1016/j.envres.2022.112933)
42.	Vacek L., Dvorak A., Bechynska K., Kosek V., Elkalaf M., Trinh M.D., Fiserova I., Pospisilova K., Slovakova L., Vitek L., Hajslova J., Polak J.: Hypoxia Induces Saturated Fatty Acids Accumulation and Reduces Unsaturated Fatty Acids Independently of Reverse Tricarboxylic Acid Cycle in L6 Myotubes. Frontiers in Endocrinology (2022). 13: 663625. (doi: 10.3389/fendo.2022.663625)

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Publikace / Publications

2021

1.	Baranski M., Srednicka-Tober D., Rempelos R., Hasanaliyeva G., Gromadzka-Ostrowska J., Skwarlo-Sonta K., Krolikowski T., Rembialkowska E., Hajslova J., Schulzova V., Cakmak I., Ozturk L., Hallmann E., Seal Ch., Iversen P.O., Vigar V., Leifert C.: Feed Composition Differences Resulting from Organic and Conventional Farming Practices Affect Physiological Parameters in Wistar Rats—Results from a Factorial, Two-Generation Dietary Intervention Trial. Nutrients (2021) 13: 377 (doi: 10.3390/nu13020377)
2.	Bechynska K., Kosek V., Fenclova M., Muchova L., Smid V., Suk J., Chalupsky K., Sticova E., Hurkova K., Hajslova J., Vitek L., Stranska M.: The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease. Biomolecules (2021) 11: 1723. (doi: 10.3390/biom11111723)
3.	Bechynska K., Kosek V., Zlechovcova M., Peukertova P., Hajlsova J.: Cannabis Metabolomic Data Processing: Challenges to be Addressed. LCGC (2021) Special Issues 34(s10): 11-15. (on-line)
4.	Belkova B., Chytilova L., Kocourek V., Slukova M., Mastovska K., Kyselka J., Hajslova J.: Influence of dough composition on the formation of processing contaminants in yeast-leavened wheat toasted bread. Food Chemistry (2021) 338: 127715 (doi: 10.1016/j.foodchem.2020.127715)
5.	Birse N., Chevallier O., Hrbek V., Kosek V., Hajslova J., Elliot Ch.: Ambient mass spectrometry as a tool to determine poultry production system history: A comparison of rapid evaporative ionisation mass spectrometry (REIMS) and direct analysis in real time (DART) ambient mass spectrometry platforms. Food Control (2021). 123: 107740 (doi: 10.1016/j.foodcont.2020.107740)
6.	Blazkova B., Pastorkova A., Solansky I., Veleminsky M. Jr., Veleminsky M., Urbancova K., Vondraskova V., Hajslova J., Pulkrabova J., Sram R.J.: Determining the Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children: A Case Study in the Czech Republic. Recent Developments in Medicine and Medical Research (2021) 10. (doi: 10.9734/bpi/rdmmr/v10/14385D)
7.	Bokšová A., Kazda J., Stejskalová M., Šubrt T., Uttl L., Mráz P., Jan Bartoška: Findings of herbicide and fungicide residues in bee bread. PLANT, SOIL AND ENVIRONMENT (2021) 67(6): 343-352. (doi: 10.17221/135/2021-PSE)
8.	Drábová L.,Mráz P., Krátký F., Uttl L., Vacková P., Schusterova D., Zadražilová B., Kadlec V., Kocourek V., Hajšlová J.: Assessment of pesticide residues in citrus fruit on the Czech market. Food Additives and Contaminants: Part A (2021) 39(2): 311-319. (doi: 10.1080/19440049.2021.2001579)
9.	Dropa T., Dzuman Z., Jonatova P.: Mycotoxins in oat flakes – changes during production and occurrence on the Czech market. Czech Journal of Food Sciences (2021) 39: 131–139. (doi: 10.17221/247/2020-CJFS)
10.	Dvorakova D., Pulkrabova J., Gramblicka T., Polachova A., Buresova M., Hajslova J., López M.E., Castaño A., Nübler S., Haji-Abbas-Zarrabi K., Klausner N., Göen T., Mol H., Koch H.M., Vaccher V., Antignac J.-P., Haug L.S., Vorkamp K.: Interlaboratory Comparison Investigations (ICIs) and External Quality Assurance Schemes (EQUASs) for Flame Retardant Analysis in Biological Matrices: Results from the HBM4EU Project. Environmental Research (2021) 202: 111705. (doi: 10.1016/j.envres.2021.111705)
11.	Gaca A., Kludska E., Hradecky J., Hajslova J., Jelen H.H.: Changes in volatile compound profiles in cold-pressed oils obtained from various seeds during accelerated storage. Molecules (2021) 23(2): 285. (doi: 10.3390/molecules26020285)
12.	Gratz M., Sevenich R., Hoppe T., Schottroff F., Vlaskovic N., Belkova B., Chytilova L, Filatova M., Stupak M., Hajslova J., Rauh C., Jaeger H.: Gentle Sterilization of Carrot-Based Purees by High-Pressure Thermal Sterilization and Ohmic Heating and Influence on Food Processing Contaminants and Quality Attributes. Frontiers in Nutrition (2021). 8: 643837. (doi: 10.3389/fnut.2021.643837)
13.	Hajnal J.E., Kos J., Malachova A., Steiner D., Stranska M., Krska R., Sulyok M.: Mycotoxins in maize harvested in Serbia in the period 2012–2015. Part 2: Non-regulated mycotoxins and other fungal metabolites. Food Chemistry (2021) 317: 126409. (doi: 10.1016/j.foodchem.2020.126409)
14.	Jafari S., Guercetti J., Geballa-Koukoula A., Tsagkaris A.S., Nelis J.L.D., Marco M.-P., Salvador J.-P., Gerssen A., Hajslova J., Elliott Ch., Campbell K., Miglirelli D., Burr L., Generelli S., Nielen M. W. F., Sturla S.J.: ASSURED Point-of-Need Food Safety Screening: A Critical Assessment of Portable Food Analyzers. Foods (2021) 10(6): 1399. (doi: 10.3390/foods10061399)
15.	Jezkova Z., Schulzova V., Krizova I., Karabin M.,Branyik T.: Influence of Cultivation Conditions on the Sioxanthin Content and Antioxidative Protection Effect of a Crude Extract from the Vegetative Mycelium of Salinispora tropica. Drugs (2021) 19(9): 509. (doi: 10.3390/md19090509)
16.	Jiru M., Stranska-Zachariasova M., Kohoutkova J., Schulzova V., Krmela A., Revenco D., Koplik R., Kastanek P., Fulin T., Hajslova J.: Potential of microalgae as source of health-beneficial bioactive components in produced eggs. Journal of Food Science and Technology (2021) 58(11): 4225-4234. (doi: 10.1007/s13197-020-04896-3)
17.	Jursík M., Hamouzová K., Hajšlová J.: Dynamics of the degradation of acetyl-coa carboxylase herbicides in vegetables. Foods (2021) 10(2): 405. (doi: 10.3390/foods10020405)
18.	Koudela M., Schulzova V., Krmela A., Chmelarova H., Hajslova J., Novotny C.: Effect of Agroecological Conditions on Biologically Active Compounds and Metabolome in Carrot. Cells (2021) 104: 784. (doi: 10.3390/cells10040784)
19.	Koulis G.A., Tsagkaris A.S., Aalizadeh R., Dasenaki M.E., Panagopoulou E.I., Drivelos S., Halagarda M., Georgiou C.A., Proestos Ch., Thomaidis N.S.: Honey Phenolic Compound Profiling and Authenticity Assessment Using HRMS Targeted and Untargeted Metabolomics. Molecules (2021) 26(9): 2769. (doi: 10.3390/molecules26092769)
20.	Kulisova M., Vrublevskaya M., Lovecka P., Vrchotova B., Stranska M., Kolarik M., Kolouchova I.: Fungal endophytes of Vitis vinifera – plant growth promotion factors. AGRICULTURE-BASEL (2021). 11(12): 1250. (doi: 10.3390/agriculture11121250)
21.	López M.A., Göen T., Mol H., Nübler S., Haji-Abbas-Zarrabi K., Koch H.M., Kasper-Sonnenberg M., Dvorakova D., Hajslova J., Antignac J.P., Vaccher V., Elbers I., Thomsen C., Vorkamp K., Pedraza – Díaz S., Kolossa-Gehring M., Castaño A.: The European human biomonitoring platform - Design and implementation of a laboratory quality assurance/quality control (QA/QC) programme for selected priority chemicals. International Journal of Hygiene and Environmental Health (2021) 234: 113740. (doi:10.1016/j.ijheh.2021.113740)
22.	Louckova A., Hurkova K., Hajslova J.: Characterization of Biologically Active Compounds in Agrimonia eupatoria. Chemicke listy (2021) 115 (9): 487-490. (on-line)
23.	Maly M., Hajsl M., Bechynska K., Kucerka O., Sramek M., Suttnar J., Hlavackova A., Hajslova J., Kosek V.: Lipidomic analysis to assess oxidative stress in acute coronary syndrome and acute stroke patients. Metabolites (2021) 11(7): 412. (doi: 10.3390/metabo11070412)
24.	Navratilova K., Hurkova K., Hrbek V., Uttl L., Tomaniova M., Valli E., Hajslova J.: Metabolic fingerprinting strategy: Investigation of markers for the detection of extra virgin olive oil adulteration with soft-deodorized olive oils. Food Control (2021), p 108649 (doi: 10.1016/j.foodcont.2021.108649)
25.	Nübler S., López M.E., Castaño A., Mol H., Schäfer M., Haji-Abbas-Zarrabi K., Bury D., Koch H.M., Vaccher V., Antignac J.-P., Dvorakova D., Hajslova J., Thomsen C., Vorkamp K., Göen T.: Interlaboratory comparison investigations (ICI) and external quality assurance schemes (EQUAS) for cadmium in urine and blood: Results from the HBM4EU project. International Journal of Hygiene and Environmental Health (2021) 234: 113711 (doi: 10.1016/j.ijheh.2021.113711)
26.	Oppeltova P., Kasal P., Kratky F., Hajslova J.: Analysis of Selected Water Quality Indicators from Runoff during Potato Cultivation after Natural Precipitation. Agriculture-Basel (2021) 11(12): 1220. (doi: 10.3390/agriculture11121220)
27.	Ovesna J., Hrbek V., Svoboda P., Pianta V., Kučera L., Hajslova J., Milella L.: Microsatellite fingerprinting and metabolite profiling for the geographical authentication of commercial green teas. Journal of Food Composition and Analysis (2021) 101: 103981. (doi: 10.1016/j.jfca.2021.103981)
28.	Panovská Z., Ilko V., Doležal M.: Air Quality as a Key Factor in the Aromatisation of Stores: A Systematic Literature Review. Applied Sciences (2021) 11(16): 7697. (doi: 10.3390/app11167697)
29.	Polachova A., Gramblicka T., Bechynska K., Parizek O., Turnerova, Dvorakov, Honkova K., Rossnerova A., Rossner P., Sram R.J., Topinka J., Pulkrabova J.: Biomonitoring of 89 POPs in blood serum samples of Czech city policemen. Environmental Pollution (2021) 291: 118140 (doi: 10.1016/j.envpol.2021.118140)
30.	Schmidt C.S., Mrnka L., Lovecka P., Frantik T., Fenclova M., Demnerova K., Vosatka M.: Bacterial and fungal endophyte communities in healthy and diseased oilseed rape and their potential for biocontrol of Sclerotinia and Phoma disease. Scientific Reports (2021) 11 (1): article No 3180. (doi: 10.1038/s41598-021-81937-7)
31.	Schottroff F., Lasarus T., Stupak M., Hajslova J., Fauster T., Jäger H.: Decontamination of herbs and spices by gamma irradiation and low-energy electron beam treatments and influence on product characteristics upon storage. Journal of Radiation Research and Applied Sciences (2021) 14(1): 380-395. (doi:10.1080/16878507.2021.1981112)
32.	Schusterova D., Hajslova J., Kocourek V., Pulkrabova J.: Pesticide residues and their metabolites in grapes and wines from conventional and organic farming system. Foods (2021) 10(2): 307. (doi: 10.3390/foods10020307)
33.	Stranska M., Lovecka P., Vrchotova B., Uttl L., Bechynska K., Behner A., Hajslova J.: Bacterial endophytes from Vitis vinifera L. - metabolomics characterization of plant-endophyte crosstalk. Chemistry & Biodiversity (2021) 18(12): e2100516. (doi: 10.1002/cbdv.202100516)
34.	Stranska M., Uttl L., Bechynska K., Hurkova K., Behner A., Hajslova J.: Metabolomic fingerprinting as a tool for authentication of grapevine (Vitis vinifera L.) biomass used in food production. Food Chemistry (2021) 361: 130166. (doi: 10.1016/j.foodchem.2021.130166)
35.	Stupak M., Filatova M., Kocourek V., Hajslova J.: Gas Chromatography Tandem Mass Spectrometry Analysis of Ethylene Oxide: An Emerged Contaminant in Seeds and Spices. LCGC (2021) Special Issues 34(s10): 5-10. (on-line)
36.	Suk J., Hamouzova K., Hajslova J., Jursik M.: Dynamics of herbicides degradation in carrot (Daucus carota l.) roots and leaves. Plant, Soil and Environment (2021) 67(6): 353-359. (doi: 10.17221/46/2021-PSE)
37.	Tittlemier S.A., Brunkhorst J., Cramer B., DeRosa M.C., Lattanzio V.M.T., Malone R., Maragos C., Stranska M., Sumarah M.W.: Developments in mycotoxin analysis: An update for 2019-2020. World Mycotoxins Journal (2021) 14(1): 3-26. (doi: 10.3920/WMJ2020.2664)
38.	Tomasko J., Stupak M., Hajslova J., Pulkrabova J.: Application of the GC-HRMS based method for monitoring of short- and medium-chain chlorinated paraffins in vegetable oils and fish. Food Chemistry (2021) 355: 129640. (doi: 10.1016/j.foodchem.2021.129640)
39.	Tomasko, J., Stupak, M., Parizkova, D., Polachova, A., Sram, R.J., Topinka, J., Pulkrabova, J.: Short- and medium-chain chlorinated paraffins in human blood serum of Czech population. Science of the Total Environment (2021) 797: 149126. (doi: 10.1016/j.scitotenv.2021.149126)
40.	Tsagkaris, A.S., Koulis G.A., Danezis G.P., Martakos I., Dasenaki M., Georgiou C.A., Thomaidis N.S.: Honey authenticity: analytical techniques, state of the art and challenges. RSC Advances (2021) 11: 11273. (doi: 10.1039/D1RA00069A)
41.	Tsagkaris A.S., Prusova N., Dzuman Z., Pulkrabova J., Hajslova J.: Regulated and Non-Regulated Mycotoxin Detection in Cereal Matrices Using an Ultra-High-Performance Liquid Chromatography High-Resolution Mass Spectrometry (UHPLC-HRMS) Method. Toxins (2021) 13(11): 783. (doi: 10.3390/toxins13110783)
42.	Tsagkaris, A.S., Pulkrabova, J., Hajslova, J.: Optical Screening Methods for Pesticide Residue Detection in Food Matrices: Advances and Emerging Analytical Trends. Foods (2021) 10(1): 88. (doi: 10.3390/foods10010088)
43.	Urbancova K., Sram R.J., Hajslova J., Pulkrabova J.: Concentrations of Phthalate and DINCH Metabolites in Urine Samples from Czech Mothers and Newborns. Exposure and Health (2021) 14: 17-27 (doi: 10.1007/s12403-021-00415-7)
44.	Vitova M., Stranska M., Palyzova A., Rezanka T.: Detailed structural characterization of cardiolipins from various biological sources using a complex analytical strategy comprising fractionation, hydrolysis and chiral chromatography. Journal of Chromatography A (2021) 1648: 462185. (doi: 10.1016/j.chroma.2021.462185)

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Publikace / Publications

2020

1.	Benes F., Fenclova M., Peukertova P., Binova Z., Dzuman Z., Hajslova J.: Determination of seventeen phytocannabinoids in various matrices by UHPLC-HRMS/MS. LCGC Europe (2020) 33(1): 8-16. Fulltext
2.	Bhave A., Schulzova V., Mrnka L., Hajslova J.: Influence of harvest date and post-harvest treatment on carotenoids and flavonoids composition in French marigold flowers. Journal of Agricultural and Food Chemistry (2020). 68(30): 7880-7889. (doi: 10.1021/acs.jafc.0c02042)
3.	Blazkova B., Pastorkova A., Solansky I., Veleminsky Jr. M., Veleminsky M., Urbancova K., Vondraskova V., Hajslova J., Pulkrabova J., Sram R.J.: Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children. Brain Sceinces (2020) 10, 619. (doi: :10.3390/brainsci10090619)
4.	Budinska E., Gojda J., Heczkova M., Bratova M., Dankova H., Wohl P., Bastova H., Lanska V., Kostovcik M., Dastych M., Senkyrik M., Krizova J., Mraz M., Hradecky J., Hajslova J., Lenicek M., Podzimkova K., Chalupsky K., Sedlacek R., Cahova M.: Microbiome and Metabolome Profiles Associated With Different Types of Short Bowel Syndrome: Implications for Treatment. Journal of parenteral and enteral nutrition (2020) 44(1): 105-118. (doi: 10.1002/jpen.1595)
5.	Cadkova Z., Szakova J., Mukhtorova D., Hlava J., Pulkrabova J., Balik J., Tlustos P., Vadlejch J.: The response of soil nematode Caenorhabditis elegans on the sewage sludge-derived micropollutants. Journal of Hazardous Materials (2020) 384: 121468. (doi: 10.1016/j.jhazmat.2019.121468)
6.	Cavanna D., Hurkova K., Dzuman Z., Serani A., Serani M., Dall´Asta Ch., Tomaniova M., Hajslova J., Suman M.: A Non-Targeted High-Resolution Mass Spectrometry Study for Extra Virgin Olive Oil Adulteration with Soft Refined Oils: Preliminary Findings from Two Different Laboratories. ACS Omega (2020) accepted (doi: 10.1021/acsomega.0c00346)
7.	Cerna M., Grafnetterova A.P., Dvorakova D., Pulkrabova J., Maly M., Janos T., Vodrazkova N., Tupa Z., Puklova V.: Biomonitoring of PFOA, PFOS and PNFNA in human milk from Czech Republic, time trends and estimation of infant’s daily intake. Environmental Research (2020) 188: 109763. (doi: 10.1016/j.envres.2020.109763)
8.	Ciesarova Z., Murkovic M., Cejpek K., Kreps F., Tobolkova B., Koplik R., Belajova E., Kukurova K., Dasko L., Panovska Z., Revenco D., Burcova Z.: Why is sea buckthorn (Hippophae rhamnoides L.) so exceptional? A review. Food Research International (2020) 133, 109170. (doi: 10.1016/j.foodres.2020.109170)
9.	Dzuman Z., Jonatova P., Stranska-Zachariasova M., Prusova N., Brabenec O., Novakova A., Fenclova M., Hajslova J.: Development of a new LC‒MS method for accurate and sensitive determination of 33 pyrrolizidine and 21 tropane alkaloids in plant-based food matrices. Analytical and Bioanalytical Chemistry (2020). 412(26): 7155-7167. (doi: 10.1007/s00216-020-02848-6)
10.	Fenclova M., Stranska-Zachariasova M., Benes F., Novakova A., Jonatova P., Kren V., Vitek L., Hajslova J.: Liquid chromatography–drift tube ion mobility–mass spectrometry as a new challenging tool for the separation and characterization of silymarin flavonolignans. Analytical and Bioanalytical Chemistry (2020) 412(4): 819-832. (doi: 10.1007/s00216-019-02274-3)
11.	Hajnal E. J., Kos J., Malachova A., Steiner D., Stranska M., Krska R., Sulyok M.: Mycotoxins in maize harvested in Serbia in the period 2012–2015. Part 2: Non-regulated mycotoxins and other fungal metabolites. Food Chemistry (2020) 317, 126409. (doi: 10.1016/j.foodchem.2020.126409. Corrigendum: 10.1016/j.foodchem.2021.129524)
12.	Hoang L., Benes F., Fenclova M., Kronusova O., Svarcova V., Rehorova K., Svecova E. B., Vosatka M., Hajslova J., Kastanek P., Viktorova J., Ruml T.: Phytochemical Composition and In Vitro Biological Activity of Iris spp. (Iridaceae): A New Source of Bioactive Constituents for the Inhibition of Oral Bacterial Biofilms. Antibiotics (2020) 9:403 (doi: 10.3390/antibiotics9070403)
13.	Horska T., Kocourek F., Stara J., Holy K., Mraz P., Kratky F., Kocourek V., Hajslova J.: Evaluation of pesticide residue dynamics in lettuce, onion, leek, carrot and parsley. Foods (2020) 9 (5), 680. (doi: 10.3390/foods9050680)
14.	Hrbek V., Zdenkova K., Jilkova D., Cermakova E., Jiru M., Demnerova K., Pulkrabova J., Hajslova J.: Authentication of meat and meat products using triacylglycerols profiling and by DNA analysis. Foods (2020) 9, 1269. (doi: 10.3390/foods9091269)
15.	Huml L., Drabek O., Pohorela B., Kotikova Z., Umar M., Miksatkova P., Kokoska L.: Analysis of nutrients and compounds potentially reducing risks of overweightness and obesity-related diseases in raw and roasted Adenanthera pavonina seeds from Samoa. Emirates Journal of Food and Agriculture (2020) 32(2): 100-108. (doi: 10.9755/ejfa.2020.v32.i2.2067)
16.	Jonatova P., Dzuman Z., Prusova N., Hajslova J., Stranska-Zachariasova M.: Occurrence of ochratoxin A and its stereoisomeric degradation product in various types of coffee available in the Czech market. World Mycotoxin Journal (2020) 13(1): 97-107. (doi: 10.3920/WMJ2019.2507)
17.	Kos J., Hajnal E.J., Malachova A., Steiner D., Stranska M., Krska R., Poschmaier B., Sulyok M.: Mycotoxins in maize harvested in Republic of Serbia in the period 2012–2015. Part 1: Regulated mycotoxins and its derivatives. Food Chemistry (2020) 312: 126034. (doi: 10.1016/j.foodchem.2019.126034. Corrigendum: 10.1016/j.foodchem.2021.129615)
18.	Kosek V., Heczkova M., Novak F., Meisnerova E., Novakova O., Zelenka J., Bechynska K., Vrzacova N., Suttnar J., Hlavackova A., Dankova H., Bratova M., Daskova N., Malinska H., Oliyarnyk O., Wohl P., Bastova H., Cahova M.: The ω-3 polyunsaturated fatty acids and oxidative stress in long-term parenteral nutrition dependent adult patients: Functional lipidomics approach. Nutrients (2020) 12(8) 2351. (doi: 10.3390/nu12082351)
19.	Krmela A., Kharoshka A., Schulzova V., Pulkrabova J., Hajslova J.: A Simple LC–MS Multi-Analyte Method to Determine Food Additives and Caffeine in Beverages. LCGC Europe (2020) 33(7): 327-335. Fulltext
20.	Nelis J.L.D., Tsagkaris A.S., Dillon M. J., Hajslova J., Elliot C.T.: Smartphone-based optical assays in the food safety field. Trends in Analytical Chemistry (2020), 129: 115934. (doi: 10.1016/j.trac.2020.115934)
21.	Pavelkova P., Krmela A., Schulzova V.: Determination of carotenoids in flowers and food supplements by HPLC-DAD. Acta Chimica Slovaca (2020) 13 (1): 6-12. (doi: 10.2478/acs-2020-0002)
22.	Polachova A., Gramblicka T., Parizek O., Sram R.J., Stupak M., Hajslova J., Pulkrabova J.: Estimation of human exposure to polycyclic aromatic hydrocarbons (PAHs) based on the dietary and outdoor atmospheric monitoring in the Czech Republic. Environmental Research (2020) 182: 108977. (doi: 10.1016/j.envres.2019.108977)
23.	Rektorisova, M.; Hrbek, V.; Jiru, M.; Ovesna, J.; Hajslova, J.: Variability in S-alk(en)yl-l-cysteine sulfoxides in garlic within a seven-month period determined by a liquid chromatography – tandem mass spectrometry method). Plant Foods for Human Nutrition (2020) 75: 376–382. (doi: 10.1007/s11130-020-00817-z)
24.	Rollova M., Gharwalova L., Krmela A., Schulzova V., Hajslova J., Jaros P., Kolouchova I., Matatkova O. (2020): Grapevine extracts and their effect on selected gut-associated microbiota: In vitro study. Czech Journal of Food Sciences (2020) 38(3): 137-143. (doi: 10.17221/308/2019-CJFS)
25.	Sabolova M., Zeman V., Lebedova G., Dolezal M., Soukup J., Reblova Z.: Relationship between the fat and oil composition and their initial oxidation rate during storage. Czech Journal of Food Sciences (2020) 38(6): 404-409 (doi: 10.17221/207/2020-CJFS)
26.	Sevenich R., Rauh C., Belkova B., Hajslova J.: Chapter 6 - Effect of high-pressure thermal sterilization (HPTS) on the reduction of food processing contaminants (e.g., furan, acrylamide, 3-MCPD-esters, HMF). Book Present and Future of High Pressure Processing (2020)139-172 (doi: 10.1016/B978-0-12-816405-1.00006-6)
27.	Tittlemier S.A., Cramer B., Dall´Asta C., Iha M.H., Lattanzio V.M.T., Maragos C., Solfrizzo M., Stranska M., Stroka J., Sumarah M.: Development in mycotoxins analysis: an update for 2018-2019. World Mycotoxin Journal (2020) 13(1): 3-24. (doi: 10.3920/WMJ2019.2535)
28.	Tsagkaris A.S., Migliorelli D., Uttl L., Filippini D., Pulkrabova J., Hajslova J.: A microfluidic paper-based analytical device (μPAD) with smartphone readout for chlorpyrifos-oxon screening in human serum. Talanta (2020) 121535. (doi: 10.1016/j.talanta.2020.121535)
29.	Tsagkaris A.S., Uttl L., Pulkrabova J., Hajslova J.: Screening of carbamate and organophosphate pesticides in food matrices using an affordable and simple spectrophotometric acetylcholinesterase assay. Applied Sciences (2020) 10(2):565. (doi: 10.3390/app10020565)
30.	Urbancova K., Dvorakova D., Gramblicka T., Sram R.J., Hajslova J., Pulkrabova J.: Comparison of polycyclic aromatic hydrocarbon metabolite concentrations in urine of mothers and their newborns. Science of the Total Environment (2020) 723:138116 (doi: 10.1016/j.scitotenv.2020.138116)
31.	Van Nguyen T., Viktorova J., Augustynkova K., Jelenova N., Dobiasova S., Rehorova K., Fenclova M., Stranska-Zachariasova M., Vitek L., Hajslova J., Ruml T.: In Silico and In Vitro Studies of Mycotoxins and Their Cocktails; Their Toxicity and Its Mitigation by Silibinin Pre-Treatment. Toxins (2020), 12, 148. (doi: 10.3390/toxins12030148)
32.	Viktorova J., Stupak M., Rehorova K., Dobiasova S., Hoang L., Hajslova J., Thanh T., Tri L., Tuan N., Ruml T.: Lemon Grass Essential Oil Does not Modulate Cancer Cells Multidrug Resistance by Citral—Its Dominant and Strongly Antimicrobial Compound. Foods (2020) 9(5):585 (doi: 10.3390/foods9050585)

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Publikace / Publications

2019

1.	Bechynska K., Daskova N., Vrzackova N., Harant K., Heczkova M., Podzimkova K., Bratova M., Dankova H., Berkova Z., Kosek V., Zelenka J., Hajslova J., Sedlacek R., Suttnar J., Hlavackova A., Bartonova L., Cahova M.: The effect of omega-3 polyunsaturated fatty acids on the liver lipidome, proteome and bile acid profile: parenteral versus enteral administration. Scientific Reports (2020) 9: 19097. (doi: 10.1038/s41598-019-54225-8)
2.	Chatterjee N.S., Chevallier O.P., Wielogorska E., Black C., Elliott C.T.: Simultaneous authentication of species identity and geographical origin of shrimps: untargeted metabolomics to recurrent biomarker ions. Journal of Chromatography A (2019) 1599: 75-84. (doi: 10.1016/j.chroma.2019.04.001)
3.	Choi H., Song W., Wang M., Sram R.J., Zhang B.: Benzo[a]pyrene is associated with dysregulated myelo-lymphoid hematopoiesis in asthmatic children. Environment International (2019) 128: 218-232. (doi:10.1016/j.envint.2019.04.052)
4.	Drabova L., Alvarez-Rivera G., Suchanova M., Schusterova D., Pulkrabova J., Tomaniova M., Kocourek V., Chevallier O., Elliot Ch., Hajslova J.: Food fraud in oregano: pesticide residues as adulteration markers. Food Chemistry (2019) 276:726-734. (doi:10.1016/j.foodchem.2018.09.143)
5.	Eskola M., Elliot Ch. T., Hajslova J., Steiner D., Krska R.: Towards a dietary-exposome assessment of chemicals in food: An update on the chronic health risks for the European consumer. Critical Reviews in Food Science and Nutrition (2019) published on-line. (doi: 10.1080/10408398.2019.1612320)
6.	Eskola M., Kos G., Elliot Ch. T., Hajslova J., Mayar S., Krska R.: Worldwide contamination of food-crops with mycotoxins: Validity of the widely cited ‘FAO estimate’ of 25%. Critical Reviews in Food Science and Nutrition (2019) published on-line. (doi: 10.1080/10408398.2019.1658570)
7.	Ezekiel Ch. N., Ayeni K. I., Ezeokoli O. T., Sulyok M., van Wyk D. A., Oyedele O. A., Akinyemi O. M., Chibuzor-Onyema I. E., Adeleke R. A., Nwangburuka C. C., Hajslova J., Elliott Ch. T., Krska R.: High-Throughput Sequence Analyses of Bacterial Communities and Multi-Mycotoxin Profiling During Processing of Different Formulations of Kunu, a Traditional Fermented Beverage. Frontiers in Microbiology (2019) 9: 3282. (doi: 10.3389/fmicb.2018.03282)
8.	Faltusová Z., Vaculová K., Pavel J., Svobodová I., Hajšlová J., Ovesná J.: Fusarium culmorum Tri genes and barley Hvugt13248 gene transcription in infected barley cultivars. Plant protection Science (2019) 55 (3): 172-180. (doi: 10.17221/21/2018-PPS)
9.	Fenclova M., Novakova A., Viktorova J., Jonatova P., Dzuman Z., Ruml T., Kren V., Hajslova J., Vitek L., Stranska-Zachariasova M.: Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes. Scientific Reports (2019) 9: 11118. (doi:10.1038/s41598-019-47250-0)
10.	Fersahl M., Yankovych H., Studenyak Y., Bazel Y., Koplik R., Revenco D.: Combination of sequential injection analysis with an integrated [BF4]-potentiometric sensor for the kinetic determination of boron. Sensors and Actuators B - Chemical (2019) 297: UNSP 126778. (doi: 10.1016/j.snb.2019.126778)
11.	Fišnar J., Sabolová M., Réblová Z.: Relationship between tocopherols depletion and polymerised triacylglycerols formation during heating of vegetable oils. Czech Journal of Food Sciences (2019) 36(6): 441-451. (doi: 10.17221/73/2018-CJFS)
12.	Humhal T., Kronusová O., Kaštánek P., Potočár T., Kohoutková J., Brányik T.: Influence of nitrogen sources on growth of thraustochytrids in waste water from the demineralization of cheese whey. Czech Journal of Food Sciences (2019) 37(5): 383-390. (doi: 10.17221/172/2018-CJFS)
13.	Hurkova K., Uttl L., Rubert J., Navratilova K., Kocourek V., Stranska- Zachariasova M., Paprstein F., Hajslova J.: Cranberries versus lingonberries: A challenging authentication of similar Vaccinum fruit. Food Chemistry (2019) 284:162-170. (doi: 10.1016/j.foodchem.2019.01.014)
14.	Jiru M., Stranska-Zachariasova M., Dzuman Z., Hurkova K., Tomaniova M., Stepan R., Cuhra P., Hajslova J.: Analysis of phosphodiesterase type 5 inhibitors as possible adulterants of botanical-based dietary supplements: extensive survey of preparations available at the Czech market. Journal of Pharmaceutical and Biomedical Analysis (2019) 164:713-724 (doi:10.1016/j.jpba.2018.11.007)
15.	Jiru M., Stranska-Zachariasova M., Kocourek V., Krmela A., Tomaniova M., Rosmus J., Hajslova J.: Authentication of meat species and net muscle proteins: updating of an old concept. Czech Journal of Food Sciences (2019) 37:205-211. (doi: 10.17221/94/2019-CJFS)
16.	Kana A., Loula M., Koplik R.,Vosmanska M., Mestek O.: Peak bordering for ultrafast single particle analysis using ICP-MS. Talanta (2019) 197: 189-198. (doi:10.1016/j.talanta.2019.01.030)
17.	Kendall H., Clark B., Rhymer C., Kuznesof S., Hajslova J., Tomaniova M., Brereton P., Frewer L.: A systematic review of consumer perceptions of food fraud and authenticity: A European perspective. Trends of Food Science & Technology (2019). 94: 79-90. (doi: 10.1016/j.tifs.2019.10.005)
18.	Kosek V., Uttl L., Jiru M., Black C., Chevallier O., Tomaniova M., Elliot C.T., Hajslova J.: Ambient mass spectrometry based on REIMS for the rapid detection of adulteration of minced meats by the use of a range of additives. Food Control (2019) 104: 50-56. (doi: 10.1016/j.foodcont.2018.10.029)
19.	Lankova D., Novakova A., Svobodova V., Hajslova J., Novotny T., Dibusz K., Nic M.: Extensive literature search and selection for relevance of studies related to the chemistry and toxicity of glycoalkaloids and quinolizidine alkaloids in food and feed – Final Report. EFSA Journal (2019) 167(11): 1348E. (doi: 10.2903/sp.efsa.2019.EN-1348)
20.	Logerova H., Tuma P., Stupak M., Pulkrabova J., Dlouhy P.: Evaluation of the burdening on the Czech population by brominated flame retardants. International Journal of Environmental Research and Public Health (2019) 16(21) 4105. (doi: 10.3390/ijerph16214105 )
21.	Loula M., Kaňa A., Koplík R., Hanuš J., Vosmanská M., Mestek O.: Analysis of Silver Nanoparticles Using Single-Particle Inductively Coupled Plasma – Mass Spectrometry (ICP-MS): Parameters Affecting the Quality of Results. Analytical Letters (2019), 52(2):288-307. (doi: 10.1080/00032719.2018.1459657)
22.	Navratilova K., Hrbek V., Kratky F., Hurkova K., Tomaniova M., Pulkrabova J., Hajslova J.: Green tea: authentication of geographic origin based on UHPLC-HRMS fingerprints. Journal of Food Composition and Analysis (2019) 78:121-128. (doi:10.1016/j.jfca.2019.02.004)
23.	Nelis J.L.D., Tsagkaris A.S., Zhao Y., Lou-Franco J., Nolan P., Zhou H., Cao C., Rafferty K., Hajslova J., Elliott C.T., Campbell K.: The end user sensor tree: An end-user friendly sensor database. Biosensors and Bioelectronics (2019) 130:245-253 (doi:10.1016/j.bios.2019.01.055)
24.	Ojuri O. T., Ezekiel C. N., Eskola M. K., Šarkanj B., Babalola A.D., Sulyok M., Hajšlová J., Elliott C. T., Krska R.: Mycotoxin co-exposures in infants and young children consuming household- and industrially-processed complementary foods in Nigeria and risk management advice. Food Control (2019) 98: 312-322. (doi: 10.1016/j.foodcont.2018.11.049)
25.	Paldrychová, M., Kolouchová, I., Vaňková, E., Maťátková, O., Šmidrkal, J., Krmela, A., Schulzová, V., Hajšlová, J., Masák, J.: Effect of resveratrol and Regrapex-R-forte on Trichosporon cutaneum biofilm. Folia Microbiologica (2019) 64(1):73-81. (doi: 10.1007/s12223-018-0633-0)
26.	Pulkrabova J., Cerny J., Szakova J., Svarcova A., Gramblicka T., Hajslova J., Balik J., Tlustos P.: Is the long-term application of sewage sludge turning soil into a sink for organic pollutants?: evidence from field studies in the Czech Republic. Journal of Soils and Sediments (2019) 19: 2445-2458. (doi:10.1007/s11368-019-02265-y)
27.	Revenco D., Vomackova M., Jelinek L., Mestek O., Koplik R.: Selenium species in selenium-enriched malt. Kvasny prumysl (2019) 65 (4) 134-141. (doi: 10.18832/kp2019.65.134)
28.	Schusterova D., Suchanova M., Pulkrabova J., Kocourek V., Urban J., Hajslova J.: Can occurrence of pesticide metabolites detected in crops provide the evidence on illegal practices in organic farming? Journal of Agricultural and Food Chemistry (2019) 67(22): 6102-6115. (doi:10.1021/acs.jafc.8b06999 )
29.	Stiborova H., Kronusova O., Kastanek P., Brazdova L., Lovecka P., Jiru M., Belkova B., Poustka J., Stranska M., Hajslova J., Demnerova K.: Waste products from the poultry industry: a source of high-value dietary supplements. Journal of Chemical Technology and Biotechnology (2019) (doi: 10.1002/jctb.6131)
30.	Susakate S., Poapolathep S., Chokejaroenrat Ch., Tanhan P., Hajslova J., Giorgi M., Saimek K., Zhang Z., Poapolathep A.: Multiclass analysis of antimicrobial drugs in shrimp muscle by ultra high performance liquid chromatography-tandem mass spectrometry. Journal of Food and Drug Analysis (2019) 27 (1): 118-134. (doi:10.1016/j.jfda.2018.06.003)
31.	Svarcova A., Lankova D., Gramblicka T., Stupak M., Hajslova J., Pulkrabova J.: Integration of five groups of POPs into one multi-analyte method for human blood serum analysis: An innovative approach within biomonitoring studies. Science of The Total Environment (2019) 667: 701-709. (doi: 10.1016/j.scitotenv.2019.02.336)
32.	Szakova J., Pulkrabova J., Cerny J., Mercl F., Svarcova A., Gramblicka T., Najmanova J., Tlustos P., Balik J.: Selected persistent organic pollutants (POPs) in the rhizosphere of sewage sludge-treated soil: Implications for the biodegradability of POPs. Archives of Agronomy and Soil Science (2019) 65(7): 994-1009. (doi:10.1080/03650340.2018.1543945)
33.	Tittlemier S. A., Cramer B., Dall'Asta C., Iha M. H., Lattanzio V. M. T., Malone R. J., Maragos C., Solfrizzo M., Stranska-Zachariasova M., Stroka J.: Developments in mycotoxin analysis: an update for 2017-2018. World Mycotoxin Journal (2019) 12 (1): 3-29. (doi:10.3920/WMJ2018.2398)
34.	Tsagkaris A.S., Nelis J.L.D., Ross G.M.S., Jafari S., Guercetti J., Kopper K., Zhao Y., Rafferty K., Salvador J.P., Migliorelli D., Salentijn G.I.J., Campbell K., Marco M.P., Elliot C.T., Nielen M.W.F., Pulkrabova J., Hajslova J.: Critical assessment of recent trends related to screening and confirmatory analytical methods for selected food contaminants and allergens. Trends in Analytical Chemistry (2019) 121: 115688. (doi: 10.1016/j.trac.2019.115688)
35.	Tsagkaris A.S., Pulkrabova J., Hajslova J., Filippini D.: A Hybrid Lab-on-a-Chip Injector System for Autonomous Carbofuran Screening. Sensors (2019) 19: 5579. (doi: 10.3390/s19245579)
36.	Urbancova K., Lankova D., SramR.J., Hajslova J., Pulkrabova J.: Urinary metabolites of phthalates and di-iso-nonyl cyclohexane-1,2-dicarboxylate (DINCH) – Czech mothers´ and newborns´ exposure biomarkers. Environmental Research (2019), 173: 342-348. (doi: 10.1016/j.envres.2019.03.067)
37.	Uttl L., Hurkova K., Kocourek V., Pulkrabova J., Tomaniova M. Hajslova J.: Metabolomics-based authentication of wines according to grape variety. Czech Journal of Food Sciences (2019) 37(4): 239-245. (doi: 10.17221/82/2019-CJFS)
38.	Vaclavik L., Benes F., Fenclova M, Hricko J., Krmela A., Svobodova V., Hajslova J., Mastovska K.: Quantitation of Cannabinoids in Cannabis Dried Plant Materials, Concentrates, and Oils Using Liquid Chromatography-Diode Array Detection Technique with Optional Mass Spectrometric Detection: Single-Laboratory Validation Study, First Action 2018.11. Journal of AOAC International (2019) 102(6): 1822-1833. (doi: 10.5740/jaoacint.18-0426)
39.	Viktorova J., Stranska-Zachariasova M., Fenclova M., Vitek L., Hajslova J., Kren V., Ruml T.: Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements. Antioxidants (2019) 8, 317. (doi: 10.3390/antiox8080317)
40.	Welten R.D., Meneely J.P., Chevallier O.P., Kosek V., Greer B., Hajslova J., Elliot Ch.T.: Oral Microcystin-LR Does Not Cause Hepatotoxicity in Pigs: Is the Risk of Microcystin-LR Overestimated? Exposure and Health (2019) pp 1-18. (doi: 10.1007/s12403-019-00336-6)
41	Wielogorska E., Ahmed Y., Meneely J., Graham W.G., Elliott C.T., Gilmore B.F.: A holistic study to understand the detoxification of mycotoxins in maize and impact on its molecular integrity using cold atmospheric plasma treatment. Food Chemistry (2019) 301: UNSP 125281. (doi: 10.1016/j.foodchem.2019.125281)
42.	Wielogorska E., Mooney M., Eskola M., Ezekiel Ch., Stranska M., Krska R., Elliott Ch.: Occurrence and Human Health Impacts of Exposure to Mycotoxins in Somalia. Journal of Agriculture and Food Chemistry (2019) 67(7):2052-2060. (doi: 10.1021/acs.jafc.8b05141)

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Publikace / Publications

2018

1.	Belkova B., Hradecky J., Hurkova K., Forstova V., Vaclavik L., Hajslova J.: Impact of vacuum frying on quality of potato crisps and frying oil. Food Chemistry (2018) 241: 51-59. (doi: 10.1016/j.foodchem.2017.08.062)
2.	Berthiller F., Cramer B., Iha M.H., Krska R., Lattanzio V.M.T., MacDonald S., Malone R.J., Maragos C., Solfrizzo M., Stranska-Zachariasova M., Stroka J., Tittlemier S.A.: Developments in mycotoxin analysis: An update for 2016-2017. (doi: 10.3920/WMJ2017.2250)
3.	Ezekiel Ch. N., Ayeni K. I., Ezeokoli O. T., Sulyok M., van Wyk D. A., Oyedele O. A., Akinyemi O. M., Chibuzor-Onyema I. E., Adeleke R. A., Nwangburuka C. C., Hajslova J., Elliott Ch. T., Krska R.: High-Throughput Sequence Analyses of Bacterial Communities and Multimycotoxin Profiling During Processing of Different Formulations of Kunu. A Traditional Beverage. Frontiers in Microbiology (2018) 9:3282. (doi: 10.3389/fmicb.2018.03282)
4.	Fisnar J., Sabolova M., Reblova Z.: Relationship Between Tocopherols Depletion and Polymerised Triacylglycerols Formation During Heating of Vegetable Oils. Czech Journal of Food Sciences (2018) 36(6): 441-451. (doi: 10.17221/73/2018-CJFS)
5.	Gracka A., Majcher M., Kludská E., Hradecky J., Hajslov J., Jelen H.H.: Storage-Induced Changes in Volatile Compounds in Argan Oils Obtained rom Raw and Roasted Kernels. Journal of the American Oil Chemists Society (2018) 95 (12): 1475-1485. (doi: 10.1002/aocs.12148)
6.	Hanus O., Krizova L., Hajslova J., Lojza J., Klimesova M., Janu L., Roubal P., Kopecky J., Jedelska R.: Effect of Increasing Zearalenone Levels on the Coagulation Properties of Milk and the Viability of Yogurt Bacteria. Czech Journal of Food Sciences (2018) 36(4): 277-283. (doi: 10.17221/391/2017-CJFS)
7.	Hrbek, V., Rektorisova, M., Chmelarova, H., Ovesna, J., Hajslova, J.: Authenticity assessment of garlic using a metabolomic approach based on high resolution mass spectrometry. Journal of Food Composition and Analysis (2018) 67: 19-28. (doi: 10.1016/j.jfca.2017.12.020 )
8.	Koplik R., Prugar J., Davidek J.: Other toxic compounds. Natural Toxic Compounds of Food (2018) 143-163. (doi: 10.1201/9781351074933)
9.	Kouřimská L., Čítek J., Zadinová K, Okrouhlá M. Panovská Z., Yunus Khatri Y., Stupka R.: Sensory Quality of Meat from Crossbred Boars in Relation to their Age and Slaughter Weight. Czech Journal of Food Sciences (2018) 36 (5): 415-419. (doi: 10.17221/151/2018-CJFS)
10.	Kyselka J., Matějková K., Šmidrkal J., Berčíková M., Pešek E., Bělková B., Ilko V., Doležal M., Filip V.: Elimination of 3-MCPD fatty acid esters and glycidyl esters during palm oil hydrogenation and wet fractionation. European Food Research and Technology (2018) 244 (11):1887-1895. (doi: 10.1007/s00217-018-3101-9 )
11.	Malachová A., Stránská M., Václavíková M., Elliott C.T., Black C., Meneely J., Hajšlová J., Ezekiel C.N., Schuhmacher R., Krska R.: Advanced LC–MS-based methods to study the co-occurrence and metabolization of multiple mycotoxins in cereals and cereal-based food. Analytical and Bioanalytical Chemistry (2018) 410 (3): 801-825. (doi: 10.1007/s00216-017-0750-7)
12.	Meneely J.P., Hajšlová J., Krska R., Elliott C.T.: Assessing the combined toxicity of the natural toxins, aflatoxin B1, fumonisin B1 and microcystin-LR by high content analysis. Food and Chemical Toxicology. (2018) 121: 527-540. (doi:10.1016/j.fct.2018.09.052)
13.	Novotny C., Schulzova V., Krmela A., Hajslova J., Svobodova K., Koudela M.: Ascorbic Acid and Glucosinolate Levels in New Czech Cabbage Cultivars: Effect of Production System and Fungal Infection. Molecules (2018) 23(8): 1855. (doi: 10.3390/molecules23081855)
14.	Ojuri O. T., Ezekiel N. C., Sulyok M., Ezeokoli O. T., Oyedele O. A., Ayeni K. I., Eskola M. K., Šarkanj B., Hajslova J., Adeleke R. A., Nwangburuka C. C., Elliott C. T., Krska R.: Assessing the mycotoxicological risk from consumption of complementary foods by infants and young children in Nigeria. Food and Chemical Toxicology (2018) 121:37-50. (doi: 10.1016/j.fct.2018.08.025)
15.	Prchal M., Vandeputte M., Gela D., Doležal M., Buchtová H., Rodina M., Flajšhans M., Kocour M.: Estimation of genetic parameters of fatty acids composition in flesh of market size common carp (cyprinus carpio L.) and their relation to performance traits revealed that selective breeding can indirectly affect flesh quality. Czech Journal of Animal Science (2018) 63 (7): 280-291. (doi: 10.17221/30/2018-CJAS)
16.	Richterova D., Fabelova L., Patayova H., Pulkrabova J., Lankova D., Rausova K., Sovcikova E., Stencl J., Hajslova J., Trnovec T., Palkovicova Murinova L.: Determinants of prenatal exposure to perfluoroalkyl substances in the Slovak birth cohort. Environment International (2018) 121 (2):1304-1310. (doi:10.1016/j.envint.2018.10.051)
17.	Righetti L., Fenclova M., Dellaﬁora L., Hajslova J., Stranska-Zachariasova M., Dall'Asta Ch.: High resolution-ion mobility mass spectrometry as an additional powerful tool for structural characterization of mycotoxin metabolites. Food Chemistry (2018) 245: 768-774. (doi: org/10.1016/j.foodchem.2017.11.113)
18.	Righetti L., Rubert J., Galaverna G., Hurkova K., Dall'Asta C., Hajslova J., Stranska-Zachariasova M.: A novel approach based on untargeted lipidomics reveals differences in the lipid pattern among durum and common wheat. Food Chemistry (2018) 240: 775-783. (doi: 10.1016/j.foodchem.2017.08.020)
19.	Rubert J., Hurkova K., Stranska M., Hajslova J.: Untargeted metabolomics reveals links between Tiger nut (Cyperus esculentus L.) and its geographical origin by metabolome changes associated with membrane lipids. Food Additives & Contaminants: Part A(2018) 35 (4): 605–613. (doi: 10.1080/19440049.2017.1400694)
20.	Sabolová M., Czornyj Š., Fišnar J., Doležal M., Sosnová M., Matějková K., Réblová Z.: Tocochromanol content in commercially prepared fried foods. Czech Journal of Food Sciences (2018) 36 (5): 392-402. (doi: 10.17221/143/2018-CJFS)
21.	Stejskalova M., Konradyova V., Suchanova M., Kazda J.: Is pollinator visitation of Helianthus annuus (sunflower) influenced by cultivar or pesticide treatment? Crop Protection (2018) 114: 83-89. (doi: 10.1016/j.cropro.2018.08.018
22.	Stupak M., Goodall I., Tomaniova M., Pulkrabova J., Hajslova J.: A novel approach to assess the quality and authenticity of Scotch Whisky based on gas chromatography coupled to high resolution mass spectrometry. Analytica Chimica Acta (2018) 1042:60-70. (doi: 10.1016/j.aca.2018.09.017
23.	Suk J., Jursik M., Suchanova M., Schusterova D., Hamouzova K.: Dynamics of herbicide degradation in cauliflower. Plant, Soil and Environment (2018) 64(11):551-556. (doi:10.17221/312/2018-PSE)

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Publikace / Publications

2017

1.	Berthiller F., Brera C., Iha M.H., Krska R., Lattanzio V.M.T., MacDonald S., Malone R.J., Maragos C., Solfrizzo M., Stranska-Zachariasova M., Stroka J., Tittlemier S.A.: Developments in mycotoxin analysis: an update for 2015-2016, Review Article. World Mycotoxin Journal (2017) 10 (1): 5-29. (doi: 10.3920/WMJ2016.2138)
2.	Bhave A., Schulzova V., Chmelarova H., Mrnka L., Hajslova J.: Assessment of the rosehips based on their biologically active compound content. Journal of Food and Drug Analysis (2017) 25 (3): 681-690. (doi: 10.1016/j.jfda.2016.12.019 )
3.	Gbelcová H., Rimpelová S., Ruml T., Fenclová M., Kosek V., Hajšlová J., Strnad H., Kolár M., Vítek L.: Variability in statin-induced changes in gene expression profiles of pancreatic cancer. Scientific Reports (2017) 7: 44219. (doi: 10.1038/srep44219)
4.	Gracka A., Raczyk M., Hradecky J., Hajslova J., Jeziorski S., Karlovits G., Michalak B., Bąk N. and Jeleń H.: Volatile compounds and other indicators of quality for cold-pressed rapeseed oils obtained from peeled, whole, flaked, and roasted seeds. European Journal of Lipid Science Technology (2017) 119 (10): . (doi:10.1002/ejlt.201600328)
5.	Hradecky J., Kludska E., Belkova B., Wagner M., Hajslova, J.: Ohmic heating: A promising technology to reduce furan formation in sterilized vegetable and vegetable/meat baby foods. Innovative Food Science and Emerging Technologies (2017) 43: 1-6. (doi: 10.1016/j.ifset.2017.07.018)
6.	Hrbek V., Krtkova V., Rubert J., Chmelarova H., Demnerova K., Ovesna J., Hajslova J.: Metabolomic Strategies Based on High-Resolution Mass Spectrometry as a Tool for Recognition of GMO (MON 89788 Variety) and Non-GMO Soybean: a Critical Assessment of Two Complementary Methods. Food Analytical Methods (2017), 10 (11): 3723-3737. (doi: 10.1007/s12161-017-0929-8)
7.	Humhal T., Kastanek P., Jezkova Z., Cadkova A., Kohoutkova J., Branyik T.: Use of saline waste water from demineralization of cheese whey for cultivation of Schizochytrium limacinum PA-968 and Japonochytrium marinum AN-4. Bioprocess and Biosystems Engineering (2017) 40 (3): 395-402. (doi: 10.1007/s00449-016-1707-5)
8.	Hurkova K., Rubert J., Stranska-Zachariasova M., Hajslova J.: Strategies to Document Adulteration of Food Supplement Based on Sea Buckthorn Oil: a Case Study. Food Analytical Methods (2017) 10 (5): 1317-1327. (doi: 10.1007/s12161-016-0674-4)
9.	Jursik M., Kovacova J., Kocarek M., Hamouzova K., Soukup J.: Effect of a non-woven fabric covering on the residual activity of pendimethalin in lettuce and soil. Pest Management Science (2017) 73 (5): 1024-1030. (doi: 10.1002/ps.4421)
10.	Kahl J. , Busscher N., Doesburg P., Mergardt G., Will F., Schulzova V., Hajslova J., Ploeger A.: Application of Crystallization with Additives to Cloudy and Clear Apple Juice. Food Analytical Methods (2017) 10 (1): 247-255. (doi: 10.1007/s12161-016-0575-6)
11.	Kocourek F., Stará J., Holý K., Horská T., Kocourek V., Kováčová J., Kohoutková J., Suchanová M., Hajšlová J.: Evaluation of pesticide residue dynamics in Chinese cabbage, head cabbage and cauliflower. Food Additives & Contaminants: Part A (2017) 34 (6): 980-989. (doi: 10.1080/19440049.2017.1311419)
12.	Kosek V., Stránská M., Fenclová M., Ruml T., Vítek L., Hajšlová J.: High resolution mass spectrometry based method applicable for a wide range of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors in blood serum including intermediates and products of the cholesterol biosynthetic pathway. Journal of Chromatography A (2017) 1489: 86-94. (doi: 10.1016/j.chroma.2017.01.084 )
13.	Nguyen D., Novakova A., Spurna K., Hricko J., Phung H., Viktorova J., Stranska M., Hajslova J., Ruml T.: Antidiabetic Compounds in Stem Juice from Banana. Journal of Food Science (2017) 35 (5): 407 - 413. (doi: 10.17221/172/2017-CJFS)
14.	Poapolathep S., Tanhan P., Piasai O., Imsilp K., Hajslova J., Giorgi M., Kumagai S., Poapolathep A.: Occurrence and Health Risk of Patulin and Pyrethroids in Fruit Juices Consumed in Bangkok, Thailand. Journal of Food Protection (2017) 80 (9): 1415-1421. (doi: 10.4315/0362-028X.JFP-17-026)
15.	Roberts D., Hajslova J., Pulkrabova J., Silcock P.: Identifying whiskey adulteration by GC/MS through chemical profiling and differential analysis. American Laboratory (2017) 49 (3): 12-15.
16.	Rubert J., Monforte A., Hurkova K., Pérez-Martínez G., Blesa J., Navarro J.L., Stranka M., Soriano J.M., Hajslova J.: Untargeted metabolomics of fresh and heat treatment Tiger nut (Cyperus esculentus L.) milks reveals further insight into food quality and nutrition. Journal of Chromatography A (2017) 1514 (8): 80-87. (doi:10.1016/j.chroma.2017.07.071)
17.	Rubert J., Righetti L., Stranska-Zachariasova M., Dzuman Z., Chrpova J., Dall'Asta C., Hajslova J.: Untargeted metabolomics based on ultra-high-performance liquid chromatography–high-resolution mass spectrometry merged with chemometrics: A new predictable tool for an early detection of mycotoxins. Food Chemistry (2017) 224: 423-431. (doi: 10.1016/j.foodchem.2016.11.132 )
18.	Sabolová M., Johanidesová A., Hasalíková E., Fišnar J., Doležal M., Réblová, Z.: Relationship between the composition of fats and oils and their oxidative stability at different temperatures, determined using the Oxipres apparatus. European Journal of Lipid Science and Technology (2017) 119 (9). (doi: 10.1002/ejlt.201600454)
19.	Sabolová M., Pohořelá B., Fišnar J., Chrpová D., Kouřimská L., Pánek J.: Formation of oxysterols during thermal processing and frozen storage of cooked minced meat. Journal of the Science od Food and Agriculture (2017) 97(15): 5092-5099. (doi: 10.1002/jsfa.8386)
20.	Socas-Rodríguez B., Lanková D., Urbancová K., Krtková V., Hernández-Borges J., Rodríguez-Delgado M. A., Pulkrabová J., Hajšlová J.: Multiclass analytical method for the determination of natural/synthetic steroid hormones, phytoestrogens, and mycoestrogens in milk and yogurt. Analytical and Bioanalytical Chemistry (2017) 409 (18): 4467-4477. (doi: 10.1007/s00216-017-0391-x)
21.	Sochorova L., Hanzlikova L., Cerna M., Drgacova A., Fialova A., Svarcova A., Gramblicka T., Pulkrabova J.: Perfluorinated alkylated substances and brominated flame retardants in serum of the Czech adult population. International Journal of Hygiene and Environmental Health (2017) 220 (2A): 235-243. (doi: 10.1016/j.ijheh.2016.09.003)
22.	Sram R. J., Ambroz A., Dostal M., Honkova K., Hajslova J., Pulkrabova J., Urbancova K., Kosek V., Veleminsky M.,Jr.: THE OSTRAVA REGION, CZECH REPUBLIC: IMPACT OF AIR POLLUTION ON CHILDREN’S HEALTH. PUBLIC HEALTH PANORAMA (2017) 3 (20): 156-164.
23.	Stiborova H., Kolar J., Vrkoslavova J., Pulkrabova J., Hajslova J., Demnerova K., Uhlik O.: Linking toxicity profiles to pollutants in sludge and sediments. Journal of Hazardous Materials (2017) 321: 672-680. (doi: 10.1016/j.jhazmat.2016.09.051)
24.	Stranska-Zachariasova M., Kurniatanty I, Gbelcova H., Jiru M., Rubert J., Nindhia T.G.T., D’Acunto C.W., Sumarsono S.H., Tan M.I., Hajslova J., Ruml T.: Bioprospecting of Turbinaria macroalgae as a potential source of health protective compounds. Chemistry & Biodiversity (2017), 14 (2): e1600192. (doi: 10.1002/cbdv.201600192)
25.	Stupak M, Kocourek V., Kolouchova I., Hajslova J.: Rapid approach for the determination of alcoholic strength and overall quality check of various spirit drinks and wines using GC–MS. Food Control (2017) 80: 307-313 (doi: 10.1016/j.foodcont.2017.05.008)
26.	Sumikova T., Chrpova J., Dzuman Z., Salava J., Sterbova L., Palicova J., Slavikova P., Stranska-Zachariasova M., Hajslova J.: Mycotoxins content and its association with changing patterns of Fusarium pathogens in wheat in the Czech Republic. World Mycotoxin Journal (2017) 10 (2) 143-151. (doi: 10.3920/WMJ2016.2133)
27.	Urbancova K., Lankova D., Rossner P., Rossnerova A., Svecova V., Tomaniova M., Veleminsky M., Jr., Sram R. J., Hajslova J., Pulkrabova J.: Evaluation of 11 polycyclic aromatic hydrocarbon metabolites in urine of Czech mothers and newborns. Science of the Total Environment (2017) 577: 212–219. (doi: 10.1016/j.scitotenv.2016.10.165)
28.	Vytejčková S., Vápenka L., Hradecký J., Dobiáš J., Hajšlová J., Loriot C., Vannini L., Poustka J.: Testing of polybutylene succinate based films for poultry meat packaging. Polymer Testing (2017) 60: 357–364. (doi: 10.1016/j.polymertesting.2017.04.018)

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Publikace / Publications

2016

1.	Ambroz A., Vlkova V., Rossner P. Jr., Rossnerova A., Svecova V., Milcova A., Pulkrabova J., Hajslova J., Veleminsky M. Jr., Solansky I., Sram R. J.: Impact of air pollution on oxidative DNA damage and lipid peroxidation in mothers and their newborns. International Journal of Hygiene and Environmental Health (2016) 219: 545–556. (doi:10.1016/j.ijheh.2016.05.010)
2.	Chrpova J., Sip V., Sumikova T., Salava J., Palicova J., Stockova L., Dzuman Z., Hajslova J.: Occurrence of fusarium species and mycotoxins in wheat grain collected in the Czech Republic. World Mycotoxin Journal (2016) 9: 317-327. (doi: 10.3920/WMJ2015.1917)
3.	Dzuman Z., Stranska-Zachariasova M., Vaclavikova M., Tomaniova M., Veprikova Z., Slavikova P., Hajslova J.: The fate of free and conjugated mycotoxins within the production of distiller’s dried grains with solubles (DDGS). Journal of Agricultural and Food Chemistry (2016) 64: 5085-5092. (doi: 10.1021/acs.jafc.6b00304)
4.	de Jong J., López P., Mol H., Baeten V., Fernández Pierna J. A., Vermeulen P., Vincent U., Boix A., von Holst C., Tomaniova M., Hajslova J., Yang Z., Han L., MacDonald S., Haughey S. A., Elliott C. T.: Analytical strategies for the early quality and safety assurance in the global feed chain: Approaches for nitrogen adulterants in soybean meal and mineral and transformer oils in vegetable oils. Trac-Trends in Analytical Chemistry (2016) 76: 203–215. (doi:10.1016/j.trac.2015.11.003)
5.	Huml L., Miksatkova P., Novy P., Drabek O., Sabolova M., Fiedlerova V., UmarM., Tejnecky V., Pohorela B., Kourimska L., Maskova E., Tulin A., Lapcik O.,Kokoska L.: Fatty acids, minerals, phenolics and vitamins in the seeds of Inocarpus fagifer, a Pacific Island underutilized legume. Journal of Applied Botany and Food Quality (2016) 89, 264-+. (doi: 10.5073/JABFQ.2016.089.034)
6.	Lankova D., Urbancova K., Sram R.J., Hajslova J., Pulkrabova J.: A novel strategy for the determination of polycyclic aromatic hydrocarbon monohydroxylated metabolites in urine using ultra-high-performance liquid chromatography with tandem mass spectrometry. Analytical and Bioanalytical Chemistry (2016) 408: 2515–25. (doi: 10.1007/s00216-016-9350-1)
7.	Loula M. Transfer, Kaňa A., Vosmanská M., Koplík R., Mestek O.: Transfer of thallium from rape seed to rape oil is negligible and oil is fit for human consumption. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment (2016) 33: 668-673. (doi: 10.1080/19440049.2016.1160329)
8.	Mekhanoshina L., Réblová Z.: Content of Polymerised Triacylglycerols in Fat of Fried Foods. Czech Journal of Food Sciences (2016) 34: 211-216. (doi: 10.17221/372/2015-CJFS)
9.	Mitrova K., Hrbek V., Svoboda P., Hajslova J., Ovesna J.: Antioxidant activity, s-alk(en)yl-l-cysteine sulfoxide and polyphenol content in onion (allium cepa L.) cultivars are associated with their genetic background. Czech Journal of Food Sciences (2016) 34: 127-132. (doi: 10.17221/268/2015-CJFS)
10.	Mulder PPJ, De Nijs M., Castellari M., Hortos M., MacDonald S., Crews C., Hajslova J. and Stranska M.: Occurrence of tropane alkaloids in food. EFSA supporting publication 2016: EN-1140, 200 pp. (doi:10.2903/sp.efsa.2016.EN-1140)
11.	Pazderu, K., Veprikova, Z., Capouchova, I., Konvalina, P., Prokinova, E., Janovska D., Skerikova A., Honsova, H.: Changes in the content of various Fusarium mycotoxins forms in germinating winter wheat and spring barley kernels. Plant Soil and Environment (2016) 62 (1): 42-46. (doi: 10.17221/708/2015-PSE)
12.	Pulkrabova J., Stupak M., Svarcova A., Rossner P., Rossnerova A., Ambroz A., Sram R., Hajslova J.: Relationship between atmospheric pollution in the residential area and concentrations of polycyclic aromatic hydrocarbons (PAHs) in human breast milk. Science of the Total Environment (2016) 562: 640-647. (doi: 10.1016/j.scitotenv.2016.04.013)
13.	Righetti L., Rubert J., Galaverna G., Folloni S., Ranieri R., Stranska-Zachariasova M., Hajslova J., Dall´Asta C.: Characterization and discrimination of ancient grains: A metabolomics approach. International Journal of Molecular Sciences (2016) 17:1217-1230. (doi: 10.3390/ijms17081217)
14.	Rubert J., Lacina O., Zachariasova M., Hajslova J.: Saffron authentication based on liquid chromatography high resolution tandem mass spectrometry and multivariate data analysis. Food Chemistry (2016) 204: 201–209. (doi:10.1016/j.foodchem.2016.01.003)
15.	Šrám J. R., Rössner P., Jr, Rössnerová A., Dostál M., Milcová A., Švecová V., Pulkrabová J., Hajšlová J., Velemínský M., Jr: Impact of Air Pollution to Genome of Newborns. Central European Journal of Public Health (2016) 24: S40-S44. (doi: 10.21101/cejph.a4536)
16.	Stiborova H. , Branska B., Vesela T., Lovecka P., Stranska M., Hajslova J., Jiru M., Patakova P., Demnerova K.: Transformation of raw feather waste into digestible peptides and amino acids. Journal of Chemical Technology and Biotechnology (2016) 91: 1629–1637. (doi: 10.1002/jctb.4912)
17.	Stranska Zachariasova M. Book review on Masked mycotoxins in food: formation, occurrence and toxicological relevance, edited by C. Dall’Asta and F. Berthiller. World Mycotoxin Journal, 2016; 9 (4): 645-646
18.	Stranska-Zachariasova M., Kastanek P., Dzuman Z., Rubert J., Godula M., Hajslova J.: Bioprospecting of microalgae: Proper extraction followed by high performance liquid chromatographic–high resolution mass spectrometric fingerprinting as key tools for successful metabolom characterization. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences (2016) 1015–1016: 22–33. (doi:10.1016/j.jchromb.2016.01.050)

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Publikace / Publications

2015

1.	Cepák V., Přibyl P., Kohoutková J., Kaštánek P.: Optimization of cultivation conditions for fatty acid composition and EPA production in the eustigmatophycean microalga Trachydiscus minutus. Journal of Applied Phycology (2014) 26: 181–190. (doi: 10.1007/s10811-013-0119-z ).
2.	Chrpova J., Sip V., Sumikova T., Salava J., Palicova J., Stockova L., Dzuman Z., Hajslova J.: Occurrence of Fusarium species and mycotoxins in wheat grain collected in the Czech Republic. World Mycotoxin Journal (2015) 9 (2): 317-327. (doi: 10.3920/WMJ2015.1917 ).
3.	Číhal P.,Vopička O., Pilnáček K., Poustka J., Friess K., Hajšlová J., Dobiáš J., Dole P.: Aroma scalping characteristics of polybutylene succinate based films. Polymer Testing (2015) 46: 108–115. (doi: 10.1016/j.polymertesting.2015.07.006 ).
4.	D’Hollander W., de Voogt P., Herzke D., Huber S., Hajslova J., Pulkrabova J., Brambilla G., Di Filippise S.P., Bervoets L.: Occurrence of perfluorinated alkylated substances in cereals, sweets and fruit items collected in four European Countries. Chemosphere (2015) 129: 179–185. (doi: 10.1016/j.chemosphere.2014.10.011).
5.	Dzuman Z., Zachariasova M., Veprikova Z., Godula M., Hajslova J.: Multi–analyte high performance liquid chromatography coupled to high resolution tandem mass spectrometry method for control of pesticide residues, mycotoxins, and pyrrolizidine alkaloids. Analytica Chimica Acta (2015) 863: 29–40. (doi:10.1016/j.aca.2015.01.021 )
6.	Faltusová Z., Chrpová J., Salačová L., Džuman Z., Pavel J., Zachariášová M., Hajšlová J., Ovesná J.: Effect of Fusarium culmorum Tri Gene Transcription on Deoxynivalenol and D3G Levels in Two Different Barley Cultivars. Journal of Phytopathology (2015) 163: 593-603. (doi: 10.1111/jph.12359 ).
7.	Horáčková Š., Mühlhansová A., Sluková M., Schulzová V., Plocková M.: Fermentation of soymilk by yoghurt and bifidobacteria strains. Czech Journal of Food Sciences (2015) 33 (4): 313-319. (pdf )
8.	Hrbek V., Ovesná J., Demnerová K., Hajšlová J.: Využití superkritické fluidní chromatografie pro lipidomické profilování sójového a kravského mléka: Autenticita a detekce falšování. Chemické listy (2015) 109: 518-526. (pdf )
9.	Janda M., Šašek V., Chmelařová H., Andrejch J., Nováková M., Hajšlová J., Burketová L., Valentová O.: Phospholipase D affects translocation of NPR1 to the nucleus in Arabidopsis thaliana. Frontiers in Plant Science (2015) 6, Article number 59, 11p. (doi: 10.3389/fpls.2015.00059).
10.	Kubec R., Urajová P., Lacina O., Hajšlová J., Kuzma M., Zápal J.: Allium Discoloration: Color Compounds Formed during Pinking of Onion and Leek. Journal of Agricultural and Food Chemistry (2015) 63: 10192-10199. (doi: 10.1021/acs.jafc.5b04564)
11.	Lankova D., Svarcova A., Kalachova K., Lacina O., Pulkrabova J., Hajslova J.: Multi-analyte method for the analysis of various organohalogen compounds in house dust. Analytica Chimica Acta (2015) 854: 61–69. (doi: 10.1016/j.aca.2014.11.007).
12.	Kubec R., Urajová P., Lacina O., Hajšlová J., Kuzma M., Zápal J.: Allium Discoloration: Color Compounds Formed during Pinking of Onion and Leek. Journal of Agricultural and Food Chemistry (2015) 63 (46): 10192–10199. (doi: 10.1021/acs.jafc.5b04564 )
13.	Mališová K., Koplík R., Mestek O.: Speciation of mercury in terrestrial plants using vapor generation and liquid chromatography–inductively coupled plasma mass spectrometry. Analytical Letters (2015) 48: 2446–2462. (doi: 10.1080/00032719.2015.1039017 )
14.	Mastovska K., Sorenson W.R., Hajslova J., Perez R., Betz J., Perez S., Keide K., Misunis M., Wang J., Jabusch J., Schmitz J., Stepp J., Hammack W., Cook J.M., Lopez-Sanchez P., Lizak R., Wenzl T., Drabova L., Pulkrabova J., Binkley J., Staples D., Pugh S., Taffe B., Rosmus J., Bousova K., Mittendorf K.: Determination of Polycyclic Aromatic Hydrocarbons (PAHs) in seafood using gas chromatography-mass spectrometry: Collaborative study. Journal of AOAC International (2015) 98: 477–505. (doi: 10.5740/jaoacint.15-032).
15.	Réblová Z., Součková Š., Fišnar J., Koplík R.: Prooxidant capacity of thermoxidised plant oils. Czech Journal of Food Sciences (2015) 33: 416-423. (pdf )
16.	Rubert J., Lacina O., Fauhl-Hassek C., Hajslova J.: Metabolic fingerprinting based on high resolution tandem mass spectrometry: a reliable tool for wine authentication? Analytical and Bioanalytical Chemistry (2015) 406: 6791–6803. (doi: 10.1007/s00216-014-7864-y).
17.	Rubert J., Zachariasova M., Hajslova J.: Advances in high-resolution mass spectrometry based on metabolomics studies for food – a review. Food Additives & Contaminants: Part A. (2015) 32: 1685–1708. (doi: 10.1080/19440049.2015.1084539 )
18.	Sevenich R., Bark F., Kleinstueck E., Crews C., Hradecky. J., Reineke K., Lavilla M., Martinez-de-Maranon I., Briand JC.: The impact of high pressure thermal sterilization on the microbiological stability and formation of food processing contaminants in selected fish systems and baby food puree at pilot scale. Food Control. (2015) 50: 539-547. (doi:10.1016/j.foodcont.2014.09.050)
19.	Stiborova H., Vrkoslavova J., Lovecka P., Pulkrabova J., Hradkova P., Hajslova J., Demnerova K.: The aerobic biodegradation of selected polybrominated diphenyl ethers (PBDEs) in wastewater sludge. Chemospehere (2015) 118: 315–321. (doi: 10.1016/j.chemosphere.2014.09.048).
20.	Stiborova H., Vrkoslavova J., Pulkrabova J., Poustka J., Hajslova J., Demnerova K.: Dynamics of brominated flame retardants removal in contaminated wastewater sewage sludge under anaerobic conditions. Science of The Total Environment (2015) 533: 439–445. (doi: 10.1016/j.scitotenv.2015.06.131 ).
21.	Svihlikova V., Lankova D., Poustka J., Tomaniova M., Hajslova J., Pulkrabova J.: Perfluoroalkyl substances (PFASs) and other halogenated compounds in fish from the upper Labe River basin. Chemospehere (2015) 129: 170–178. (doi: 10.1016/j.chemosphere.2014.09.096).
22.	Vaclavik L., Capuano E., Gökmen V., Hajslova J.: Prediction of acrylamide formation in biscuits based on fingerprint data generated by ambient ionization mass spectrometry employing direct analysis in real time (DART) ion source. Food Chemistry (2015) 173: 290–297. (doi: 10.1016/j.foodchem.2014.09.151).
23.	Vaclavikova M., Dzuman Z., Lacina O., Fenclova M., Veprikova Z., Zachariasova M., Hajslova J.: Monitoring survey of patulin in a variety of fruit-based products using a sensitive UHPLC-MS/MS analytical procedure. Food Control (2015) 47: 577–584. (doi: 10.1016/j.foodcont.2014.07.064).
24.	Veprikova Z., Zachariasova M. , Dzuman Z., Zachariasova A., Fenclova M., Slavikova P., Vaclavikova M., Mastovska K., Hengst D., Hajslova J.: Mycotoxins in Plant-Based Dietary Supplements: Hidden Health Risk for Consumers. Journal of Agricultural and Food Chemistry (2015) 63: 6633-6643. (doi: 10.1021/acs.jafc.5b02105 ).
25.	Vermeulen P., Nietner T., Haughey S. A., Yang Z., Tena N., Chmelarova H., van Ruth S., Tomaniova M., Boix A., Han L., Elliott C. T., Baeten V., Fauhl-Hassek C.: Origin authentication of distillers’ dried grains and solubles (DDGS)—application and comparison of different analytical strategies. Analytical and Bioanalytical Chemistry (2015) 407 (21): 6447-61. (doi: 10.1007/s00216-015-8807-y ).
26.	Žitný R., Landfeld A., Skočilas J., Štancl J., Flegl V., Zachariášová M., Jírů M., Houška M.: Hydraulic characteristic of collagen. Czech Journal of Food Sciences (2015) 33: 479–485. (pdf )

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Publikace / Publications

2014

1.	Cajka T., Vaclavikova M., Dzuman Z., Vaclavik L., Ovesna J., Hajslova J.: Rapid LC-MS-based metabolomics method to study the Fusarium infection of barley. J. Sep. Sci. (2014) 37:912–919. (doi: 10.1002/jssc.201301292).
2.	Dzuman Z., Vaclavikova M., Polisenska I., Veprikova Z., Fenclova M., Zachariasova M., Hajslova J.: Enzyme-linked immunosorbent assay in analysis of deoxynivalenol: Investigation of the impact of sample matrix on results accuracy. Anal. Bioanal. Chem. (2014) 406:505–514. (doi: 10.1007/s00216-013-7463-3).
3.	Dzuman Z., Zachariasova M., Lacina O., Veprikova Z., Slavikova P., Hajslova J.: A rugged high-throughput analytical approach for the determination and quantification of multiple mycotoxins in complex feed. Talanta (2014) 121:263–272. (doi: 10.1016/j.talanta.2013.12.064).
4.	Fisnar J., Dolezal M., Reblova Z.: Tocopherol losses during pan-frying. European Journal of Lipid Science and Technology (2014) 116(12): 1694-1700. (doi: 10.1002/ejlt.201400188)
5.	Forstova V., Belkova B., Riddellova K., Vaclavik L., Prihoda J., Hajslova J.: Acrylamide formation in traditional Czech leavened wheat-rye breads and wheat rolls. Food Control (2014) 38:221–226. (doi: 10.1016/j.foodcont.2013.10.022).
6.	Hloušková V., Lanková D., Kalachová K., Hrádková P., Poustka J., Hajšlová J., Pulkrabová J.: Brominated flame retardants and perfluoroalkyl substances in sediments from the Czech aquatic ecosystem. Sci. Total. Environ (2014) 470–471:407–416. (doi: 10.1016/j.scitotenv.2013.09.074).
7.	Hrbek V., Ovesná J., Demnerová K., Hajšlová J.: Lze využít metabolomické profilování pro autenticitu geneticky modifikované sóji?: pilotní studie. Chem. Listy, (2014) 108: 875-881. (pdf )
8.	Hrbek V., Vaclavik L., Elich O., Hajslova J.: Authentication of milk and milk-based foods by direct analysis in real time ionization–high resolution mass spectrometry (DART–HRMS) technique: a critical assessment. Food Control (2014) 36:138–145. (doi: 10.1016/j.foodcont.2013.08.003).
9.	Kahl, J., Bodroza-Solarov, M., Busscher, N., Hajslova, J., Kneifel, W., Kokornaczyk, M.O., van Ruth, S., Schulzova, V., Stolz, P.: Status quo and future research challenges on organic food quality determination with focus on laboratory methods. J. Sci. Food Agr., (2014) 94: 2595-2599. (doi: 10.1002/jsfa.6553).
10.	Kouřimská L., Sabolová, M., Dvořáková B., Roubíčková I., Pánek J., Nový P.: Antioxidant activity of Lamiaceae herbs grown under organic and conventional farming. Scientia Agriculturae Bohemica (2014) 45(1):19–25. (doi: 10.7160/sab.2014.450103).
11.	Kovacova J., Kocourek V., Kohoutkova J., Lansky M., Hajslova J.: Production of apple-based baby food: changes in pesticide residues. Food Addit. Contam. A (2014) 31:1089–1099. (doi: 10.1080/19440049.2014.912356).
12.	Krtkova V., Schulzova V., Lacina O., Hrbek V., Tomaniova M., Hajslova J.: Analytical strategies for controlling polysorbate-based nanomicelles in fruit juice. Anal. Bioanal. Chem., (2014) 406: 3909-3918. (doi: 10.1007/s00216-014-7823-7).
13.	Pudil F., Uvíra R., Janda V.: Volatile compounds in stinkhorn (Phallus impudicus L. ex Pers.) at different stages of growth. Eur. Sci. J. (2014) 10:163–171. (pdf)
14.	Rubert J., Lacina O., Fauhl-Hassek C., Hajslova J.: Metabolic fingerprinting based on high resolution tandem mass spectrometry: a reliable tool for wine authentication? Anal. Bioanal. Chem., (2014) 406: 6791-680. (doi: 10.1007/s00216-014-7864-y).
15.	Zachariasova M., Cuhra P., Hajslova J.: Cross reactivity of rapid immunochemical methods for mycotoxins detection towards metabolites and masked mycotoxins: the current state of knowledge. World Mycotoxins Journal (2014), 7 (4): 449–464. (doi: 10.3920/WMJ2014.1701)
16.	Zachariasova M., Dzuman Z., Veprikova Z., Hajkova K., Jiru M., Vaclavikova M., Pospichalova M., Florian M., Hajslova J.: Occurrence of multiple mycotoxins in European feedingstuffs, assessment of dietary intake by farm animals. Anim. Feed. Sci. Tech. (2014) 193:124–140. (doi: 10.1016/j.anifeedsci.2014.02.007).

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Publikace / Publications

2013

1.	Cajka T., Danhelova H., Zachariasova M., Riddellova K., Hajslova J.: Application of direct analysis in real time ionization–mass spectrometry (DART–MS) in chicken meat metabolomics aiming at the retrospective control of feed fraud. Metabolomics (2013) 9:545–557. (doi: 10.1007/s11306-013-0495-z).
2.	Cajka T., Danhelova ., Vavrecka A., Riddellova K., Kocourek V., Vacha F., Hajslova J.: Evaluation of direct analysis in real time ionization–mass spectrometry (DART–MS) in fish metabolomics aimed to assess the response to dietary supplementation. Talanta (2013) 115: 263-270. (doi:10.1016/j.talanta.2013.04.025).
3.	Dellatte E., Brambilla G., De Filippis S. P., di Domenico A., Pulkrabova J., Eschauzier C., Klenow S., Heinemeyer G., de Voogt P.: Occurrence of selected perfluorinated alkyl acids in lunch meals served at school canteens in Italy and their relevance for children’s intake. Food Addit. Contam. A, (2013), 30:1590–159 (doi: 10.1080/19440049.2013.813648).
4.	Drabova L., Tomaniova M., Kalachova K., Kocourek V., Hajslova J., Pulkrabova J.: Application of solid phase extraction and two-dimensional gas chromatography coupled with time-of-flight mass spectrometry for fast analysis of polycyclic aromatic hydrocarbons in vegetable oils. Food Control (2013) 33: 489–497. (doi: 10.1016/j.foodcont.2013.03.018).
5.	Drabova L., Pulkrabova J., Kalachova K., Tomaniova M., Kocourek V., Hajslova J.: Polycyclic aromatic hydrocarbons (PAHs) and halogenated persistent organic pollutants (POPs) in canned fish and seafood products: smoked versus non-smoked products. Food Addit. Contam. A (2013) 30:5152–527. (doi: 10.1080/19440049.2012.755645).
6.	Herzke D., Huber S., Bervoets L., D’Hollander W., Hajslova J., Pulkrabova J., Brambilla G., De Filippis S. P., Klenow S., Heinemeyer G., de Voogt P.:PFAS in vegetables collected in four European countries; raw and processed products. Environ. Sci. Pollut. Res., (2013), 20(11):7930–7939 (doi:10.1007/s11356-013-1777-8).
7.	Hlouskova V., Hradkova P., Poustka J., Brambilla G., SDe Filipps. P., D´Hollander W., Bervoets, L. Herzke D., Huber S., de Voogt P., Pulkrabova J.:Occurrence of PFASs in various food items of animal origin collected in four European countries. Food Addit. Contam. A, (2013), 30 (11): 1918–1932. (doi: 10.1007/s11356-013-1777-8).
8.	Hloušková V., Lanková D., Kalachová K., Hrádková P., Poustka J., Hajšlová J., Pulkrabová J.: Occurrence of brominated flame retardants and perfluoroalkyl substances in fish from the Czech aquatic ecosystem. Sci. Total. Environ. (2013) 461–462:88–98. (doi:10.1016/j.scitotenv.2013.04.081).
9.	Hradkova P., Poustka J., Pulkrabova J., Hlouskova V., Kocourek V., Llorca M., Farre M., Barceló D., Hajslova J.: A fast and simple procedure for determination of perfluoroalkyl substances in food and feed: a method verification by an interlaboratory study. Anal. Bioanal. Chem., (2013) 405: 7817–7827 (doi: 10.1007/s00216-013-6962-6).
10.	Hubert J., Nesvorna M., Hujslova M., Stara J., Hajslova J., Stejskal V.: Acarus siro and Tyrophagus putrescentiae (Acari: Acarididae) transfer of Fusarium culmorum into germinated barley increases mycotoxin deoxynivalenol content in barley under laboratory conditions. International Journal of Acarology (2013) 39: 235–238. (doi:10.1080/01647954.2013.770794).
11.	Kalachova K., Cajka T., Sandy C., Hajslova J., Pulkrabova J.: High throughput sample preparation in combination with gas chromatography coupled to triple quadrupole tandem mass spectrometry (GC-MS/MS): a smart procedure for (ultra)trace analysis of brominated flame retardants in fish. Talanta (2013) 105:109–116.(doi: 10.1016/j.talanta.2012.11.073).
12.	Kalachova K., Pulkrabova J., Cajka T., Drabova L., Stupak M., Hajslova J.: Gas chromatography–triple quadrupole tandem mass spectrometry: A powerful tool for the (ultra)trace analysis of multi-class environmental contaminants in fish and fish feed. Anal. Bioanal. Chem., (2013) 405: 7803–7815 (doi: 10.1007/s00216-013-7000-4).
13.	Kaňa A., Koplík R., Eichler Š., Mestek O.: Software solution for post-column isotope dilution liquid chromatography – inductively coupled plasma mass spectrometry. Anal. Lett. (2013), ), 46: 2430–2443 (doi: 10.1080/00032719.2013.800534).
14.	Kouřimská L., Panovská Z., Legarová V., Pacáková Z.: Correlation of sensory and physiochemical properties of selected apple cultivars. Acta Alimentaria, An International Journal of Food Science (2013), 208–219. (doi: 10.1556/AAlim.42.2013.2.8).
15.	Kovacova J., Hrbek V., Kloutvorova J., Kocourek V., Drabova L., Hajslova J.: Assessment of pesticide residues in strawberries grown under various treatment regimes. Food Addit. Contam. A (2013) 30: 2123–2135. (doi: 10.1080/19440049.2013.850537 )
16.	Lankova D., Kockovska M., Lacina O., Kalachova K., Pulkrabova J., Hajslova J.: Rapid and simple method for determination of hexabromocyclododecanes and other LC–MS/MS-amenable brominated flame retardants in fish. Anal. Bioanal. Chem., (2013) 405:7829–7839 (doi:10.1007/s00216-013-7076-x).
17.	Lankova D., Lacina O., Pulkrabova J., Hajslova J.: The determination of perfluoroalkyl substances, brominated flame retardants and their metabolites in human breast milk and infant formula. Talanta (2013), 117: 318–325. (doi: 10.1016/j.talanta.2013.08.040 )
18.	Malachova A., Sulyok M., Schuhmacher R., Berthiller F., Hajslova J., Veprikova Z., Zachariasova M., Lattanzio V.M.T., De Saeger S., Di Mavungu J.D., Malysheva S.V., Biselli S., Winkelmann O., Breidbach A., Hird S., Krska R.: Collaborative investigation of matrix effects in mycotoxin determination by high performance liquid chromatography coupled to mass spektrometry. Quality Assurance and Safety of Crops & Foods (2013) 5:91–103. (doi:10.3920/QAS2012.0213).
19.	Martinez-Villalba A., Vaclavik L., Moyano E., Galceran M.T., Hajslova J.: Direct analysis in real time high-resolution mass spectrometry for high-throughput analysis of antiparasitic veterinary drugs in feed and food. Rapid. Commun. Mass. Spectrom. (2013) 27:467–475. (doi:10.1002/rcm.6466).
20.	Petersson E.V., Arif U., Schulzova V., Krtková V., Hajšlová J., Meijer J., Andersson H.C., Jonsson L., Sitbon F.: Glycoalkaloid and calystegine levels in table potato cultivars subjected to wounding, light, and heat treatments. J. Agr. Food Chem. (2013) 61:5893-5902. (doi: 10.1021/jf400318p).
21.	Réblová Z., Peprná T.: Představují tuky a oleje po smažení zdravotní riziko? Chem. Listy (2013) 107: 271-276. (pdf).
22.	Sevenich R., Bark F., Crews C., Anderson W., Pye C., Riddellova K., Hradecky J., Moravcova E., Reineked K., Knorr D.: Effect of high pressure thermal sterilization on the formation of food processing contaminants. Innovative Food Science & Emerging Technologies 20:42–50 (2013). (doi:10.1016/j.ifset.2013.07.006)
23.	Sousa M.A., Lacina O., Hrádková P., Pulkrabová J., Vilar V. J.P., Gonçalves C., Boaventura R. A.R., Hajšlová J., Alpendurada M.F.: Lorazepam Photofate under Photolysis and TiO₂-assisted Photocatalysis: Identification and Evolution Profiles of By-products formed during Phototreatment of a WWTP Effluent. Water Res., (2013), 47:5584–5593. (doi: 10.1016/j.watres.2013.06.029).
24.	Średnicka-Tober D., Barański M., Gromadzka-Ostrowska J., Skwarło-Sońta K., Rembiałkowska E., Hajslova J., Schulzova V., Çakmak I., Öztürk L., Królikowski T., Wiśniewska K., Hallmann E., Baca E., Eyre M., Steinshamn H., Jordon T., Leifert C.: Effect of crop protection and fertilization regimes used in organic and conventional production systems on feed composition and physiological parameters in rats. J. Agr. Food Chem (2013) 61: 1017–1029. (doi: 10.1021/jf303978n).
25.	Vaclavik L., Ovesna J., Kucera L., Hodek J., Demnerova K., Hajslova J.: Applic.ation of ultra-high performance liquid chromatography–mass spectrometry (UHPLC–MS) metabolomic fingerprinting to characterize GM and conventional maize varieties. Czech J. Food Sci. (2013), (pdf).
26.	Vaclavik L., Mishra A., Mishra K., Hajslova J.: Mass spectrometry-based metabolomic fingerprinting for screening cold tolerance in Arabidopsis thaliana accessions. Anal. Bioanal. Chem. (2013) 405:2671–2683. (doi: 10.1007/s00216-012-6692-1).
27.	Vaclavik L., Belkova B., Reblova Z., Riddellova K., Hajslova J.: Rapid monitoring of heat-accelerated reactions in vegetable oils using direct analysis in real time ionization coupled with high resolution mass spectrometry. Food Chem. (2013) 138:2312–2320.(doi: 10.1016/j.foodchem.2012.12.019).
28.	Václavíková M., Malachová A., Vepříková Z., Džuman Z., Zachariášová M., Hajšlová J.: ‘Emerging’ mycotoxins in cereals processing chains: Changes of enniatins during beer and bread making. Food Chem. (2013) 136:750–757. (doi: 10.1016/j.foodchem.2012.08.031).

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Publikace / Publications

2012

1.	Cajka T., Sandy C., Bachanova V., Drabova L., Kalachova K., Pulkrabova J., Hajslova J.: Streamlining sample preparation and gas chromatography-tandem mass spectrometry analysis of multiple pesticide residues in tea. Anal. Chim. Acta (2012) 743:51–60. (doi: 10.1016/j.aca.2012.06.051).
2.	Danhelova H., Hradecky J., Prinosilova S., Cajka T., Riddellova K., Vaclavik L., Hajslova J.: Rapid analysis of caffeine in various coffee samples employing direct analysis in real time ionization–high-resolution mass spectrometry. Anal. Bioanal. Chem. (2012) 403:2883–2889. (doi:10.1007/s00216-012-5820-2).
3.	Drabova L., Pulkrabova J., Kalachova K., Tomaniova M., Kocourek V., Hajslova J.: Rapid determination of polycyclic aromatic hydrocarbons (PAHs) in tea using Two-Dimensional Gas Chromatography coupled with Time of Flight Mass Spectrometry. Talanta (2012) 100:207–216. (doi:10.1016/j.talanta.2012.07.081).
4.	Čechovská L., Konečný M., Velíšek J., Cejpek K.: Effect of the Maillard reaction on reducing power of malts and beers. Czech J. Food Sci. (2012) 30: 548–556. (pdf).
5.	Eichler Š, Vosmanská M., Hofmanová E., Koplík R., Mestek O.: Analýza anorganických specií selenu s využitím HPLC a ICP/MS pro sledování mobility selenu v inženýrských bariérách jaderného úložiště. Chem. Listy (2012) 106: 189–194. (pdf).
6.	Hrádková P., Pulkrabová J., Kalachová K., Hloušková V., Tomaniová M., Poustka J., Hajšlová J.: Occurrence of halogenated contaminants in fish from selected river localities and ponds in the Czech Republic. Arch. Environ. Contam. Toxicol. (2012) 62:85–96. (doi: 10.1007/s00244-011-9681-z).
7.	Joudalová K., Réblová Z.: Dietary Intake of antioxidants in the Czech Republic. Czech J. Food Sci. (2012) 30: 268–275. (doi: pdf).
8.	Kalachova K., Hradkova P., Lankova D., Hajslova J., Pulkrabova J.: Occurrence of brominated flame retardants in household and car dust from the Czech Republic. Sci. Total. Environ. (2012) 441:182–193. (doi: 10.1016/j.scitotenv.2012.09.061).
9.	Kalachova K., Pulkrabova J., Cajka T., Drabova L., Hajslova J.: Implementation of comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry for the simultaneous determination of halogenated contaminants and polycyclic aromatic hydrocarbons in fish. Anal. Bioanal. Chem. (2012) 403:2813–2824. (doi: 10.1007/s00216-012-6095-3).
10.	Lacina O., Zachariasova M., Urbanova J., Vaclavikova M., Cajka T., Hajslova J.: Critical assessment of extraction methods for the simultaneous determination of pesticide residues and mycotoxins in fruits, cereals, spices and oil seeds employing ultra-high performance liquid chromatography–tandem mass spectrometry. J. Chromatogr. A (2012) 1262:8–18. (doi: 10.1016/j.chroma.2012.08.097).
11.	Lojza J., Cajka T., Schulzova V., Riddellova K., Hajslova J.: Analysis of isoflavones in soybeans employing direct analysis in real time ionization–high-resolution mass spectrometry. J. Sep. Sci. (2012) 35:476–481. (doi: 10.1002/jssc.201100882).
12.	Meneely J.P., Quinn J.G., Flood E.M., Hajšlová J., Elliott C.T.: Simultaneous screening for T-2/HT-2 and deoxynivalenol in cereals using a surface plasmon resonance immunoassay. World Mycotoxin J. (2012) 5:117–126. (doi: 10.3920/WMJ2011.1351).
13.	Mestek O., Komínková J., Šantrůček J., Kačer P., Mališová K., Koplík R.: Analyses of trace metals, peptide ligands of trace metals and mercury speciation in home prepared bread. Chem. Spec. Bioavailab. (2012) 24:79–88. (doi: 10.3184/095422912X13325261626531).
14.	Moravcova E., Vaclavik L., Lacina O., Hrbek V., Riddellova K., Hajslova J.: Novel approaches to analysis of 3-chloropropane-1,2-diol esters in vegetable oils. Anal. Bioanal. Chem. (2012) 402:2871–2883. (doi: 10.1007/s00216-012-5732-1).
15.	Novotná H., Kmiecik O., Galazka M., Krtková V., Hurajová A., Schulzová V., Rembialkowska E., Hajšlová J: Metabolomic fingerprinting employing DART-TOFMS for authentication of tomatoes and peppers from organic and conventional farming. Food Addit. Contam. A (2012) 29:1335–1346. (doi:10.1080/19440049.2012.690348).
16.	Panovská Z., Váchová A. Pokorný J.: Effect of thickening agents on the perceived viscosity and acidity of model beverages. Czech J. Food Sci. Vol. (2012) 30: 442–445. (pdf).
17.	Réblová Z.: Effect of temperature on the antioxidant activity of phenolic acids. Czech J. Food Sci. (2012) 30: 171–177. (pdf).
18.	Réblová Z., Fišnar J., Tichovská D., Doležal M., Joudalová K.: Effect of temperature and oil composition on the ability of phenolic acids to protect naturally present ?-tocopherol during the heating of plant oils. Czech J. Food Sci. (2012) 30: 351–357.(pdf).
19.	Rubert J., Džuman Z., Václavíková M., Zachariášová M., Soler C., Hajšlová J.: Analysis of mycotoxins in barley using ultra high liquid chromatography high resolution mass spectrometry: Comparison of efficiency and efficacy of different extraction procedures. Talanta (2012) 99:712–719. (doi:10.1016/j.talanta.2012.07.010).
20.	Schulzová V., Babička L., Hajšlová, J.: Furanocoumarins in celeriac from different farming systems: a 3-year study. J. Sci. Food Agric. (2012) 92:2849–2854. (doi: 10.1002/jsfa.5629).
21.	Siříšťová L., Přinosilová Š., Riddellová K., Hajšlová J., Melzoch K.: Changes in quality parameters of vodka filtered through activated charcoal. Czech J. Food Sci. (2012) 30:474–482. (pdf).
22.	Vaclavik L., Schreiber A., Lacina O., Cajka T., Hajslova J: Liquid chromatography–mass spectrometry-based metabolomics for authenticity assessment of fruit juices. Metabolomics (2012) 8:793–803. (doi: 10.1007/s11306-011-0371-7).
23.	Vaclavikova M., Malachová A., Veprikova Z., Dzuman Z., Zachariasova M., Hajslova J.: ‘Emerging’ mycotoxins in cereals processing chains: changes of enniatins during beer and bread making. Food Chemistry 136 (2012): 750–757.
24.	Valterová B., Száková J., Koplík R., Havlík J., Tlustoš P., Mestek O.: Frakcionace a speciace As, Cd a Zn v nadzemní biomase penízku modravého (Thlaspi caerulescens J. & C. Presl). Chem. Listy (2012) 106: 392–397. (pdf).
25.	Veprikova Z., Vaclavikova M., Lacina O., Dzuman Z., Zachariasova M., Hajslova J.: Occurrence of mono- and di-glucosilated conjugates of T-2 and HT-2 toxins in naturally contaminated cereals. World Mycotoxin J. (2012) 5:231–240. (doi: 10.3920/WMJ2012.1453).
26.	Zachariasova M., Vaclavikova M., Lacina O., Vaclavik L., Hajslova J.: Deoxynivalenol-oligoglycosides: new „masked“ Fusarium toxins occurring in malt, beer and breadstuff. J. Agric. Food Chem. (2012) 60:9280–9291. (doi: 10.1021/jf302069z).

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Publikace / Publications

2011

1.	Buřičová L., Andjelkovic M., Čermáková A., Réblová Z., Jurček O., Kolehmainen E., Verhé R., Kvasnička F.: Antioxidant capacity and antioxidants of strawberry, blackberry and raspberry leaves. Czech J. Food Sci. (2011) 29: 181–189. (pdf).
2.	Cajka T., Hajslova J.: Volatile compounds in food authenticity and traceability testing. In: Food Flavors: Chemical, Sensory and Technological Properties. H. Jelen (editor), ISBN: 9781439814918, CRC Press (2011) 355–411. (info).
3.	Cajka T., Riddellova K., Tomaniova M., Hajslova J.: Ambient mass spectrometry employing a DART ion source for metabolomic fingerprinting/profiling: a powerful tool for beer origin recognition. Metabolomics (2011) 7:500–508. (doi: 10.1007/s11306-010-0266-z).
4.	Cajka T., Riddellova K., Zomer P., Mol H., Hajslova J.: Direct analysis of dithiocarbamate fungicides in fruit by ambient mass spectrometry. Food Addit. Contam. A (2011) 28:1372–1382. (doi: 10.1080/19440049.2011.590456).
5.	Cajka T., Hajslova J.: Halogenated persistent organic pollutants and polycyclic aromatic hydrocarbons in food. In: Mass Spectrometry in Food Safety: Methods and Protocols. J. Zweigenbaum (editor), ISBN: 978-1617791352, Humana Press (2011) 373–410. (doi: 10.1007/978-1-61779-136-9_15).
6.	Capouchova I., Kostelanska M., Erhartova D., Prokinova E., Hajslova J., Skerikova A., Salava J., Pazderu K.: Risks of the Fusarium infestation for bioethanol production from wheat. Listy cukrovarnicke a reparske (2011) 127:95–99.
7.	Čechovská L., Cejpek K., Konečný M., Velíšek J.: On the role of 5,6-dihydro-3,5-dihydroxy-2-methyl-(4H)-pyran-4-one in antioxidant capacity of prunes. Eur. Food Chem. Technol. (2011) 233:367-376. (doi: 10.1007/s00217-011-1527-4).
8.	Drábová L., Pulkrabová J., Kalachová K., Hradecký J., Suchanová M., Tomaniová M., Kocourek V., Hajšlová J.: Novel approaches to determination of PAHs and halogenated POPs in canned fish. Czech J. Food Sci. (2011) 29:498–507.
9.	Hajslova J., Zachariasova M., Cajka T.: Analysis of multiple mycotoxins in food. In: Mass Spectrometry in Food Safety: Methods and Protocols. J. Zweigenbaum (editor), ISBN: 978-1617791352, Humana Press (2011) 233–258. (doi: 10.1007/978-1-61779-136-9_10).
10.	Hajslova J., Cajka T., Vaclavik L.: Challenging applications offered by direct analysis in real time (DART) in food-quality and safety analysis. Trend Anal. Chem. (2011) 30:204–218. (doi: 10.1016/j.trac.2010.11.001).
11.	Hamlet C.G., Asuncion L., Velíšek J., Doležal M., Zelinková Z., Crews C.: Formation and occurrence of esters of 3-chloropropane-1,2-diol (3-CPD) in foods: What we know and what we assume. Eur. J. Lipid Sci. Technol. (2011) 113: 279–303. (doi: 10.1002/ejlt.201000480).
12.	Horníčková J., Kubec, R., Velíšek J., Cejpek K., Ovesná J., Stavělíková H.: Changes of S alk(en)ylcysteine sulfoxide levels during the growth of different garlic morphotypes. Czech J. Food Sci. (2011) 29:373–381. (pdf).
13.	Ilko V., Zelinková Z., Doležal M., Velíšek J.: 3-Chloropropane-1,2-diol fatty acid esters in potato products. Czech J. Food Sci. (2011) 29: 411–419. (pdf).
14.	Kalachova K., Pulkrabova J., Drabova L., Cajka T., Kocourek V., Hajslova J.: Simplified and rapid determination of polychlorinated biphenyls, polybrominated diphenyl ethers, and polycyclic aromatic hydrocarbons in fish and shrimps integrated into a single method. Anal. Chim. Acta (2011) 707:84–91. (doi: 10.1016/j.aca.2011.09.016).
15.	Koplík R., Linková M., Mestek O.: Changes of phosphorus and trace element species in rye and oat flakes and oat porridge induced by simulated digestion. Eur. Food Res. Technol. (2011) 232:1007–1016. (doi: 10.1007/s00217-011-1471-3).
16.	Kostelanska M., Dzuman Z., Malachova A., Capouchova I., Prokinova E., Skerikova A., Hajslova J.: Effects of milling and baking technologies on levels of deoxynivalenol and its masked form deoxynivalenol-3-glucoside. J. Agric. Food Chem. (2011) 59:9303–9312. (doi: 10.1021/jf202428f).
17.	Kostelanska M., Zachariasova M., Lacina O., Fenclova M., Kollos A.-L., Hajslova J.: The study of deoxynivalenol and its masked metabolites fate during the brewing process realised by UPLC-TOFMS method. Food Chem. (2011) 126:1870–1876. (doi: 10.1016/j.foodchem.2010.12.008).
18.	Křížová L., Veselý A., Třináctý J., Schulzová V., Hurajová A., Hajšlová J., Kvasničková E., Havlíková Š.: Changes in isoflavones concentrations in cheese during processing and ripening. Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis (2011) 59:153–162.
19.	Kubec R., Krejcova P., Simek P., Vaclavik L., Hajslova J., Schraml J.: Precursors and formation of pyrithione and other pyridyl-containing sulfur compounds in drumstick onion, Allium stipitatum. J. Agric. Food Chem. (2011) 59:5763–5770. (doi: 10.1021/jf200704n).
20.	Lacina. O., Hradkova P., Pulkrabova J., Hajslova J.: Simple, high throughput ultra-high performance liquid chromatography/tandem mass spectrometry trace analysis of perfluorinated alkylated substances in food of animal origin: Milk and fish. J. Chromatogr. A (2011) 1218:4312–4321. (doi: 10.1016/j.chroma.2011.04.061).
21.	Li Z.-H., Zlabek V., Turek J., Velisek J., Pulkrabova J., Kolarova J., Sudova E., Berankova P., Hradkova P., Hajslova J., Randak T.: Evaluating environmental impact of STPs situated on streams in the Czech Republic: An integrated approach to biomonitoring the aquatic environment. Water Res. (2011) 45:1403–1413. (doi: 10.1016/j.watres.2010.10.032).
22.	Malachova A., Dzuman Z., Veprikova Z., Vaclavikova M., Zachariasova M., Hajslova J.: Deoxynivalenol, deoxynivalenol-3-glucoside, and enniatins: The major mycotoxins found in cereal-based products on the Czech market. J. Agric. Food Chem. (2011) 59:12990–12997. (doi: 10.1021/jf203391x).
23.	Meimaridou A., Kalachova K., Shelver W. L., Franek M., Pulkrabova J., Haasnoot W., Nielen M. W. F.: Multiplex screening of persistent organic pollutants in fish using spectrally encoded microspheres. Anal. Chem. (2011) 83:8696–9702. (doi: 10.1021/ac201969z).
24.	Modra H., Vrskova D., Macova S., Kohoutkova J., Hajslova J., Haluzova I., Svobodova Z.: Comparison of diazinon toxicity to embryos of Xenopus laevis and Danio rerio; Degradation of diazinon in water. Bull. Envir. Contam. Tox. (2011) 86:601–604. (doi: 10.1007/s00128-011-0273-4).
25.	Papousková L., Capouchová I., Kostelanská M., Škeříkova A., Prokinová E., Hajšlová J., Salava J., Faměra O.: Changes in baking quality of winter wheat with different intensity of fusarium spp. Contamination detected by means of new rheological system mixolab. Czech J. Food Sci. (2011) 29:420–429.
26.	Peters R., Dam G.T., Bouwmeester H., Helsper H., Allmaier G., Kammer F.V., Ramsch R., Solans C., Tomaniová M., Hajslova J., Weigel S.: Identification and characterization of organic nanoparticles in food. Trend Anal. Chem. (2011) 30:100–112. (doi: 10.1016/j.trac.2010.10.004).
27.	Réblová Z.: Vliv vnějších faktorů na aktivitu antioxidantů. Chem. Listy (2011) 105: 667–673. (pdf).
28.	Sousa M.A., Goncalves C., Cunha E., Hajslova J., Alpendurada M.F.: Cleanup strategies and advantages in the determination of several therapeutic classes of pharmaceuticals in wastewater samples by SPE-LC-MS/MS. Anal. Bioanal. Chem. (2011) 399:807–822. (doi: 10.1007/s00216-010-4297-0).
29.	Škrbić B., Malachova A., Živančev J., Veprikova Z., Hajšlová J.: Fusarium mycotoxins in wheat samples harvested in Serbia: A preliminary survey. Food Control (2011) 22:1261–1267. (doi: 10.1016/j.foodcont.2011.01.027).
30.	Šmidrkal J., Ilko V., Filip V., Doležal M., Zelinková Z., Kyselka J., Hrádková I., Velíšek J.: Formation of acylglycerol chloro derivatives in vegetable oils and mitigation strategy. Czech J. Food Sci. (2011) 29: 448–456. (pdf).
31.	Vaclavik L., Hrbek V., Cajka T., Rohlik B.-A., Pipek P., Hajslova J.: Authentication of animal fats using direct analysis in real time (DART) ionization–mass spectrometry and chemometric tools. J. Agric. Food Chem. (2011) 59:5919–5926. (doi: 10.1021/jf200734x).
32.	Vaclavik L., Lacina O., Hajslova J., Zweigenbaum J.: The use of high performance liquid chromatography-quadrupole time-of-flight mass spectrometry coupled to advanced data mining and chemometric tools for discrimination and classification of red wines according to their variety. Anal. Chim. Acta (2011) 685:45–51. (doi: 10.1016/j.aca.2010.11.018).
33.	Velíšek J., Cejpek K.: Pigments of higher fungi: a review. Czech J. Food Sci. (2011) 29: 87–102. (pdf).

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Publikace / Publications

2010

1.	Aulický R., Stejskal V., Dohnal P., Kocourek V., Plachý J., Hajšlová J.: Validation of insecticide aerosol generated by smoke-generator for German cockroach control. Int. Pest Control (2010) 52:84–86.
2.	Cajka T., Riddellova K., Tomaniova M., Hajslova J.: Recognition of beer brand based on multivariate analysis of volatile fingerprint. J. Chromatogr. A (2010) 1217:4195–4203. (doi: 10.1016/j.chroma.2009.12.049).
3.	Cajka T., Riddellova K., Klimankova E., Cerna M., Pudil F., Hajslova J.: Traceability of olive oil based on volatiles pattern and multivariate analysis. Food Chem. (2010) 121:282–289. (doi: 10.1016/j.foodchem.2009.12.011).
4.	Cunha S.C., Kalachova K., Pulkrabova J., Fernandes J.O., Oliveira M.B.P.P., Alves A., Hajslova J.: Polybrominated diphenyl ethers (PBDEs) contents in house and car dust of Portugal by pressurized liquid extraction (PLE) and gas chromatography–mass spectrometry (GC–MS). Chemosphere (2010) 78:1263–1271. (doi: 10.1016/j.chemosphere.2009.12.037).
5.	Godula M., Zachariasova M., Hajslova J.: Examining the benefits of high resolution mass spectrometry for high throughput screening of priority mycotoxins in food samples. Lab Asia, March 2010, 30–31.
6.	Hajslova J., Kalachova K., Drabova L., Kocourek V., Pulkrabova J.: Rapid sample preparation procedure for the simultaneous determination of PCBs, PBDEs and PAHs in fish. Organohal. Comp. (2010) 72.
7.	Horníčková J., Kubec R., Cejpek K., Velíšek J., Ovesná J., Stavělíková H.: Profiles of S-alk(en)ylcysteine sulfoxides in various garlic genotypes. Czech J. Food Sci. (2010) 28:298–308. (pdf).
8.	Hrádková P., Poustka J., Hloušková V., Pulkrabová J., Tomaniová M., Hajšlová J. Perfluorinated compounds: occurrence of emerging food contaminants in canned fish and seafood products. Czech J. Food Sci. (2010) 28:326–335.
9.	Chrpová, D., Kouřimská, L., Gordon, M.H., Heřmanová, V., Roubíčková, I., Pánek, J.: Antioxidant activity of selected phenols and herbs used in diets for medical conditions. Czech J. Food Sci. (2010) 28: 317–325. (pdf).
10.	Kouřimská, L., Chrpová, D., Pánek, J., Kolesárová, L., Legarová, V.: Analytické metody hodnocení účinnosti antioxidantů ve vybraných druzích koření. Chem. Listy (2010) 104:441–444. (pdf).
11.	Krajčová A., Schulzová V., Lojza J., Křížová L., Hajšlová J.: Phytoestrogens in bovine plasma and milk – LC-MS/MS analysis. Czech J. Food Sci. (2010) 28:315–325.
12.	Lacina O., Urbanova J., Poustka J., Hajslova J.: Identification/quantification of multiple pesticide residues in food plants by ultra-high-performance liquid chromatography-time-of-flight mass spectrometry. J. Chromatogr. A (2010) 1217:648–659. (doi: 10.1016/j.chroma.2009.11.098).
13.	Leitnerová D., Panovská Z., Váchová A., Boháčková B.: Posouzení čichového vnímání prostřednictvím komerčně dostupné sady pachů. Chem. Listy (2010). 104: 861–866. (pdf).
14.	Malachova A., Cerkal R., Ehrenbergerova J., Dzuman Z., Vaculova K., Hajslova J.: Fusarium mycotoxins in various barley cultivars and their transfer into malt. J. Sci. Food Agric. (2010) 90:2495–2505. (doi: 10.1002/jsfa.4112).
15.	Meimaridou A., Haasnoot W., Noteboom L., Mintzas D., Pulkrabova J., Hajslova J., Nielen M.W.F.: Color encoded microbeads-based flow cytometric immunoassay for polycyclic aromatic hydrocarbons in food. Anal. Chim. Acta (2010) 672:9–14. (doi: 10.1016/j.aca.2010.05.005).
16.	Mestek O., Komínková J., Koplík R., Šantrůček J., Polák J.: Trace elements distribution and species fractionation in the wheat (Triticum aestivum) plant. Chem. Spec. Bioavailab. (2010) 22:61–70. (doi: 10.3184/095422910X12632366016796).
17.	Pulkrabova J., Hradkova P., Vrkoslavova J., Stiborova H., Mackova M., Stavelova M., Kalachova K., Demnerova K., Hajslova J.: Contribution of BFRs and other contaminants to toxicity profiles of the Czech river sediments and sewage sludge. Organohal. Comp. (2010) 72.
18.	Pulkrabova J., Lacina O., Lankova D., Kalachova K., Hajslova J.: Novel LC–MS strategy to monitor brominated flame retardants together with their metabolites in food matrices. Organohal. Comp. (2010) 72.
19.	Réblová Z., Okrouhlá P.: Ability of phenolic acids to protect ?-tocopherol. Czech J. Food Sci. (2010) 28: 290-297. (pdf).
20.	Rohlik B.-A., Pipek P., Pánek J.: The Effect of Natural Antioxidants on the Colour of Dried/Cooked Sausages. Czech J. Food Sci. (2010) 28:249–257. (pdf).
21.	Schurek J., Nazafarin L., Kovalczuk T.: Application potential of gas chromatography high speed time-of-flight mass spectrometry system in analysis of pesticides. Part 1. J. Anal. Chem. (2010) 65:1540–1544. (doi: 10.1134/S1061934810140169).
22.	Schurek J., Pulkrabova J., Hajslova J., Nazafarin L., Kovalczuk T.: Application potential of microextraction in packed syringe coupled with gas chromatography time-of-flight mass spectrometry in analysis of brominated flame retardants in waste water. Part 2. J. Anal. Chem. (2010) 65:1545–1548. (doi: 10.1134/S1061934810140170).
23.	Stanimirova I., Üstün B., Cajka T., Riddellova K., Hajslova J., Buydens L.M.C., Walczak B.: Tracing the geographical origin of honeys based on volatile compounds profiles assessment using pattern recognition techniques. Food Chem. (2010) 118:171–176. (doi: 10.1016/j.foodchem.2009.04.079).
24.	Stavelova M., Kalachova K., Pulkrabova J., Hradkova P., Kovar M., Demnerova K., Hajslova J.: PBDEs, HBCD and other non-PBDEs flame retardants in car dust sampled in the Czech Republic in 2009. Organohal. Comp. (2010) 72.
25.	Stern P., Panovska Z., Pokorny, J.: Psychorheology of food dispersions. Journal of Hydrology and hydromechanics.(2010) 29–35. (doi: 10.2478/v10098-010-0004-2).
26.	Svobodová J., Křížová L., Pavlík A., Schulzová V., Hajšlová J., Lojza J.: The effect of soybean-derived phytoestrogens on concentrations of plasma 15-keto-13,14-dihydroprostaglandin F2a and progesterone in dairy cows. Acta Vet. Brno (2010) 79:525–532. (doi: 10.2754/avb201079040525).
27.	Vaclavik L., Zachariasova M., Hrbek V., Hajslova J.: Analysis of multiple mycotoxins in cereals under ambient conditions using direct analysis in real time (DART) ionization coupled to high resolution mass spectrometry. Talanta (2010) 82:1950–1957. (doi: 10.1016/j.talanta.2010.08.029).
28.	Vaclavik L., Rosmus J., Popping B., Hajslova J.: Rapid determination of melamine and cyanuric acid in milk powder using direct analysis in real time-time-of-flight mass spectrometry. J. Chromatogr. A (2010) 1217:4204–4211. (doi: 10.1016/j.chroma.2010.03.014).
29.	Vrana B., Mills G.A., Leonards P.E.G., Kotterman M., Weideborg M., Hajlova J., Kocourek V., Tomaniova M., Pulkrabova J., Suchanova M., Hajkova K., Herve S., Ahkola H., Greenwood R.: Field performance of the Chemcatcher passive sampler for monitoring hydrophobic organic pollutants in surface water. J. Environ. Monit. (2010) 12:863–872. (doi: 10.1039/B923073D)
30.	Vrkoslavová J., Demnerová K., Macková M., Zemanová T., Macek T., Hajšlová J., Pulkrabová J., Hrádková P., Stiborová H.: Absorption and translocation of polybrominated diphenyl ethers (PBDEs) by plants from contaminated sewage sludge. Chemosphere (2010) 81:381–386. (doi: 10.1016/j.chemosphere.2010.07.010).
31.	Zachariasova M., Cajka T., Godula M., Malachova A., Veprikova Z., Hajslova J.: Analysis of multiple mycotoxins in beer employing (ultra)-high resolution mass spectrometry. Rapid Commun. Mass Spectrom. (2010) 24:3357–3367. (doi: 10.1002/rcm.4746).
32.	Zachariasova M., Hajslova J., Godula M.: Multimycotoxin screening and quantitation in beer samples using UHPLC and high resolution and accurate mass approach. Am. Lab. (2010) 3:15–21.
33.	Zachariasova M., Lacina O., Malachova A., Kostelanska M., Poustka J., Godula M., Hajslova J.: Novel approaches in analysis of Fusarium mycotoxins in cereals employing ultra performance liquid chromatography coupled with high resolution mass spectrometry. Anal. Chim. Acta (2010) 662:51–61. (doi: 10.1016/j.aca.2009.12.034).

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Publikace / Publications

2009

1.	Cajka T., Hajslova J., Pudil F., Riddellova K.: Traceability of honey origin based on volatiles pattern processing by artificial neural networks. J. Chromatogr. A (2009) 1216:1458–1462. (doi: 10.1016/j.chroma.2008.12.066).
2.	Cejpek K., Maloušková I., Konečný M., Velíšek J.: Antioxidant activity in variously prepared elderberry food and supplements. Czech J. Food Sci.( 2009) 27:S45–S48. (pdf).
3.	Cejpek K., Velíšek J.: Advances in the chemistry of isothiocyanate-derived colorants. Czech J. Food Sci.( 2009) 27:S207–S210. (pdf).
4.	Čmejlová K; Panovská Z.; Váchová A., Lukešová D.: Time intensity study of sweeteners. Czech J. Food Sci. (2009). 27: S327–S329. (pdf).
5.	Doležal M., Kertisová J., Zelinková Z., Velíšek J.: Analysis of bread lipids for 3-MCPD esters. Czech J. Food Sci. (2009) 27: S417–S420. (pdf).
6.	Kalachová K., Pulkrabová J., Hrádková P., Poustka J., Hajšlová J.: Polybrominated diphenyl ethers (PBDEs in dust samples from Czech households. Organohal. Comp. (2009) 71:2320–2324.
7.	Konečný M., Cejpek K., Čechovská L., Velíšek J.: Transformation pathways of reductones in the advanced Maillard reaction. Czech J. Food Sci. (2009) 27: S149–S152. (pdf).
8.	Kostelanska M., Hajslova J., Zachariasova M., Malachova A., Kalachova K., Poustka J., Fiala J., Scott P.M., Berthiller F., Krska R.: Occurrence of deoxynivalenol and its major conjugate, deoxynivalenol-3-glucoside, in beer and some brewing intermediates. J. Agric. Food Chem. (2009) 57:3187–3194. (doi: 10.1021/jf803749u).
9.	Krajcova A. Schulzova V., Hajslova J., Bjelkova M.: Lignans in flaxseed. Czech J. Food Sci. (2009) 27:S252–S255.
10.	Lacmanova I., Pazlarova J., Kostelanska M., Hajslova J.: PCR-based identification of toxinogenic Fusarium species. Czech J. Food Sci. (2009) 27:90–94.
11.	Lojzova L., Riddellova K., Zrostlikova J., Schurek J., Cajka T.: Alternative GC–MS approaches in the analysis of substituted pyrazines and other volatile aromatic compounds formed during Maillard reaction in potato chips. Anal. Chim. Acta (2009) 641: 101–109. (doi: 10.1016/j.aca.2009.03.036).
12.	Macova S., Harustiakova D., Kolarova J., Machova J., Zlabek V., Vykusova B., Randak T., Velisek J., Poleszczuk G., Hajslova J., Pulkrabova J., Svobodova Z.: Leeches as sensor-bioindicators of river contamination by PCBs. Sensors (2009) 9:1807–1820. (doi: 10.3390/s90301807).
13.	Martinek P., Klem K., Vanova M., Bartackova V., Vecerkova L., Bucher P., Hajslova J.: Effects of nitrogen nutrition, fungicide treatment and wheat genotype on free asparagine and reducing sugars content as precursors of acrylamide formation in bread. Plant Soil Envir. (2009) 55:187–195.(pdf).
14.	Mestek O., Koplík R.: Dual detector calibration of PE-Elan inductively coupled plasma mass spectrometers. Chem. Anal. (Warsaw) (2009) 54:1245–1252.
15.	Panovská Z., Štern P., Váchová A., Lukešová D., Pokorný J.: Textural and flavour characteristics of commercial tomato ketchup. Czech J. Food Sci. (2009). 27:165–170. (pdf).
16.	Panovská Z., Váchová A., Řeřichová J.: Sensitivity of assessors to different ferrous salts. Czech J. Food Sci. (2009). 27: S333-S336. (pdf).
17.	Polák J., Mestek O., Koplík R., Šantrůček J., Komínková J., Kodíček M.: Trace elements species fractionation in rye flour and rye (Secale cereale L.) seedlings. Czech J. Food Sci. (2009) 27:39–48. (pdf).
18.	Pulkrabova J., Hrádková P., Hajšlová J., Poustka J., Nápravníková M., Poláček V.: Brominated flame retardants and other organochlorine pollutants in human adipose tissue samples from the Czech Republic. Environ. Int. (2008) 35:63–68. (doi: 10.1016/j.envint.2008.08.001).
19.	Pulkrabova J., Suchanova M., Hajslova J., Kocourek V., Tomaniova M.: Passive sampling of water and porous media for monitoring of organic pollutants. Chemicke Listy (2009) 103:159–165.
20.	Pulkrabova J., Kalachova K., Drabova L., Cajka T., Poustka J., Hajslova J.: Rapid method for simultaneous determination of PCBs, PBDEs and PAHs in fish samples. Organohal. Comp. (2009) 71:2230–2235.
21.	Rajchl A., Čížková H., Voldřich M., Lukešová D., Panovská Z.: Methoxypyrazines in Sauvignon Blanc Wines, Detection of Addition of Artificial Aroma. Czech J. Food Sci. (2009) 27: 259–266. (pdf).
22.	Randak T., Zlabek V., Pulkrabova J., Kolarova J., Kroupova H., Siroka Z., Velisek J., Svobodova Z, Hajslova J.: Effects of pollution on chub in the River Elbe, Czech Republic. Ecotox. Environ. Safe. (2009) 72:737–746. (doi: 10.1016/j.ecoenv.2008.09.020).
23.	Réblová Z., Tichovská D., Doležal M.: Heating of plant oils – fatty acid reactions versus tocopherols degradation. Czech J. Food Sci. (2009) 27:S185–S187. (pdf).
24.	Schulzova V., Hajslova J., Peroutka R., Hlavasek J., Gry J., Andersson H.C.: Agaritine content of 53 Agaricus species collected from nature. Food. Addit. Contam. (2009) 26:82–93. (doi: 10.1080/02652030802039903).
25.	Stavelova M., Pulkrabova J., Hradkova P., Kalachova K., Zlamalikova J., Stiborova H., Poustka J., Kovar M., Mackova M., Demnerova K., Hajslova J.: PBDEs and HBCD in sewage sludge and river sediments in the Czech Republic: A 3-year survey (2006–2008). Organohal. Comp. (2009) 71:631–636.
26.	Trinacty J., Krizova L., Schulzova V., Hajslova J., Hanus O.: The effect of feeding soybean-derived phytoestogens on their concentration in plasma and milk of lactating dairy cows. Arch. Anim. Nutr. (2009) 63:219–229. (doi: 10.1080/17450390902859739).
27.	Váchová A., Panovská Z., Lukešová D.: The selection of optimal rate of acid and sweet taste for lemon flavoured drops. Czech J. Food Sci.: (2009). 27, 330–332.
28.	Vaclavik L., Cajka T., Hrbek V., Hajslova J.: Ambient mass spectrometry employing direct analysis in real time (DART) ion source for olive oil quality and authenticity assessment. Anal. Chim. Acta (2009) 645:56–63. (doi: 10.1016/j.aca.2009.04.043).
29.	Velíšek J., Hajšlová J. a kol.: Chemie potravin I, II, nakladatelství OSSIS,Tábor, 2009, ISBN 978-80-86659-17-6. (info).
30.	Zelinková Z., Doležal M., Velíšek J.: Occurrence of 3-chloropropane-1,2-diol fatty acid esters in infant and baby foods. Eur. Food Res. Technol. (2009) 228: 571–578. (doi: 10.1007/s00217-008-0965-0).

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Bioactive secondary metabolites of plants and microorganisms

Natural toxic compounds, mycotoxins, alkaloids

◳ mykotoxiny (jpg) → (šířka 215px)

Some plants or microorganisms have the ability to synthesize complex organic compounds, products of specific secondary metabolism, generally used to protect producers from the harmful effects of the environment (predators or parasites). However, these substances are also usually toxic to humans, and can pose a significant health risk to consumers. Our working group deals mainly with mycotoxins, toxic secondary metabolites of filamentous micromycetes, and natural alkaloids, toxic products of some of the higher plants and some microscopic fungi. We work not only on the development of sensitive analytical methods based on chromatography and mass spectrometry, which are able to detect dozens of substances within a single analysis, but we also participate in the evaluation and interpretation of risks arising from the presence of these substances in food and natural products.

Publications

Dzuman Z., Jonatova P., Stranska-Zachariasova M., Prusova N., Brabenec O., Novakova A., Fenclova M., Hajslova J.: Development of a new LC‒MS method for accurate and sensitive determination of 33 pyrrolizidine and 21 tropane alkaloids in plant-based food matrices. Analytical and Bioanalytical Chemistry (2020). Accepted. (doi: 10.1007/s00216-020-02848-6)
Fenclova M., Novakova A., Viktorova J., Jonatova P., Dzuman Z., Ruml T., Kren V., Hajslova J., Vitek L., Stranska-Zachariasova M.: Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes. Scientific Reports (2019) 9: 11118. (doi:10.1038/s41598-019-47250-0)
Righetti L., Fenclova M., Dellaﬁora L., Hajslova J., Stranska-Zachariasova M., Dall'Asta Ch.: High resolution-ion mobility mass spectrometry as an additional powerful tool for structural characterization of mycotoxin metabolites. Food Chemistry (2018) 245: 768-774. (doi: 10.1016/j.foodchem.2017.11.113)

Overview of all publications:

Projects

8E18B045: New mask masked ’Fusarium mycotoxins found in malt and beer, clarification of their origin and proposal of strategies for their minimization (Ministry of Education, Youth and Sports)

Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.

20-14649S: Pulsed electric field as an innovative tool to reduce the occurrence of micromycetes of the genus Fusarium and mycotoxins in the barley-malt-beer chain (Czech Science Foundation)

Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.

16-06008S: A novel comprehensive strategy for assessment of biological effects elicited by mixtures of chemicals occurring foods and food supplements (Czech Science Foundation)

Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.

Cannabinoids

◳ kanabinoidy (jpg) → (šířka 215px)

Plant cannabinoids (phytocannabinoids) are a group of structurally diverse bioactive secondary metabolites occurring in Cannabis sativa L. plants. C. sativa and cannabinoids are now increasingly popular in connection with the production and distribution of "healthy foods" and cannabis-based dietary supplements. Besides the most well-known psychotropic tetrahydrocannabinol (THC), being produced by certain C. sativa varieties (in particular C. sativa L. var. indica), tens up to hundreds of other phytocannabinoids with numerous positive biological effects (antioxidant, anti-inflammatory, immunomodulatory, etc.) are the subject of our current interdisciplinary research. In addition to development of analytical methods for efficient separation and sensitive detection of cannabinoids in various cannabis varieties and derived products, our working group collaborates also on determination of biological availability and biological endpoints of these compounds.

It should be noted that in addition to natural phytocannabinoids, the subject of our interest are also so-called synthetic cannabinoids, substances of completely different structure, but similar pharmacological effect such as THC. Their occurrence in food has recently been observed in the Czech Republic.

Publications

Benes F., Fenclova M., Peukertova P., Binova Z., Dzuman Z., Hajslova J.: Determination of seventeen phytocannabinoids in various matrices by UHPLC-HRMS/MS. LCGC Europe (2020) 33(1): 8-16. Fulltext
Vaclavik L., Benes F., Fenclova M, Hricko J., Krmela A., Svobodova V., Hajslova J., Mastovska K.: Quantitation of Cannabinoids in Cannabis Dried Plant Materials, Concentrates, and Oils Using Liquid Chromatography-Diode Array Detection Technique with Optional Mass Spectrometric Detection: Single-Laboratory Validation Study, First Action 2018.11. Journal of AOAC International (2019) 102(6): 1822-1833. (doi: 10.5740/jaoacint.18-0426)

Overview of all publications:

Projects

TJ02000238: Development of innovative analytical strategies usable for checking the safety and authenticity of food and food raw materials (Technology Agency of the Czech Republic)

Principal Investigator at UCT Prague: doc. Ing. Milena Stránská, Ph.D.

FV40103: Biotechnology of cannabis cultivation for the production of CBD (Ministry of Industry and Trade)

Principal Investigator at UCT Prague: prof. Ing. Jana Hajšlová, CSc.

TN01000048/04: Biorefining as a circulating technology - valorization of plant biomass by biorefining processes (Technology Agency of the Czech Republic)

Principal Investigator at UCT Prague: prof. Ing. Jana Hajšlová, CSc.

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Food Chemistry and Elemental Analysis

The Maillard reaction and other non-enzymatic browning reactions in foods

◳ Obrázek1_Maillardova_reakce (png) → (originál)

We address many aspects of non-enzymatic browning reactions - monitoring the formation of aromatic, coloured, biologically and redox-active products, the reactivity of sugars, or the glycation of proteins. We mainly focus on the most important intermediates of these reactions, such as reductones and reactive carbonyl compounds. We are also interested in reducing carbonyl stressors in reactions with phenolic substances and other food components.

Publications

Cejpek K.: Vonné a chuťové složky sladů. Chemické Listy 108, 426–435, 2014.
Čechovská L., Konečný M., Velíšek J., Cejpek K.: Effect of the Maillard reaction on reducing power of malts and beers. Czech Journal of Food Sciences, 30, 548–556, 2012.

Minerals and trace elements in food

We deal with the methodology of elemental analysis of biological materials (using AAS and ICP-MS) and monitor the content of essential and toxic elements in different foods. Besides the total content, we are also interested in the chemical forms of the elements and the changes in the content of elements during food processing. We cooperate with the atomic spectrometry group of the Institute of Analytical Chemistry of the Technical University of Applied Sciences.

Publications

Fersahl M., Yankovych H., Studenyak Y., Bazel Y., Koplik R., Revenco D.: Combination of sequential injection analysis with an integrated [BF4]-potentiometric sensor for the kinetic determination of boron. Sensors and Actuators B - Chemical (2019) 297: UNSP 126778. (doi: 10.1016/j.snb.2019.126778)
Koplík R., Mestek O., Komínková J., Borková M., Suchánek M. : Effect of cooking on phosphorus and trace elements species in peas. Food Chemistry 85, 31–39, 2004.
Koplík R., Mestek O., Fingerová H., Suchánek M.: Validation protocol for the determination of copper in plant samples by isotope dilution inductively coupled plasma mass spectrometry. Journal of Analytical Atomic Spectrometry 14, 241–245, 1999.

Elemental speciation analysis

◳ Obrázek5_prvková_speciační_analýza (png) → (šířka 215px) Speciation analysis is a differentiated determination of individual forms (species, compounds) of a chemical element or fractions of these forms in a sample. Methodically, we combine different variants of liquid chromatography with ICP-MS. Among other things, we are interested in the fractions of iron, copper, zinc and other elements in legumes, cereals and pseudocereals and their possible changes during the processing of the raw materials and the digestion of the food as the representation of these fractions influences the bioavailability of the elements. We also deal with speciation analysis of selenium and mercury.

Publications

Revenco D., Vomackova M., Jelinek L., Mestek O., Koplik R.: Selenium species in selenium-enriched malt. Kvasny prumysl (2019) 65 (4) 134-141. (doi: 10.18832/kp2019.65.134)
Koplík R., Klimešová I., Mališová K., Mestek O.: Determination of mercury species in foodstuffs using LC-ICP-MS: the applicability and limitations of the method. Czech Journal of Food Sciences 32, 249–259, 2014.

Analysis of inorganic nanoparticles

◳ Obrázek6b_nanočástice_vertikálně (png) → (výška 215px)

In collaboration with the Atomic Spectrometry group of the Institute of Analytical Chemistry of the Technical University of Applied Sciences we develop methods for the determination of silver nanoparticles in samples of biological origin. We use the single particle ICP-MS technique. During the analysis, due to the very fast measurement, the signals of individual particles are recorded and sorted by size. Based on a calibration, a particle weight is assigned to them, which can be converted into a diameter in nanometres. The result is data on the number and size distribution of the particles in the sample. We are interested in the changes in the state of the nanoparticles that can occur during the processing and digestion of food.

Publications

Revenco D., Loula M., Mestek O., Koplík R.: Stanovení anorganických nanočástic v biologických materiálech a potravinách analýzou jednotlivých částic hmotnostní spektrometrií s indukčně vázaným plazmatem. Chemické Listy 113, 478–484, 2019
Loula M., Kaňa A., Koplík R., Hanuš J., Vosmanská M., Mestek O.: Analysis of Silver Nanoparticles Using Single-Particle Inductively Coupled Plasma – Mass Spectrometry (ICP-MS): Parameters Affecting the Quality of Results. Analytical Letters (2019), 52(2):288-307. (doi: 10.1080/00032719.2018.1459657)

Other areas of interest

biologically active substances of garlic and cruciferous vegetables (S-alk(en)yl-cysteine sulfoxides and their reaction products glucosinolates)
aromatic substances of mushrooms

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Pesticide/biocide residues in food and the environment

The production of crops and various natural raw materials cannot yet take place without pesticides. Depending on the target pesticide, we classify them as herbicides, fungicides, insecticides or acaricides, including plant growth regulators and repellents. Unlike persistent pesticides such as DDT and other chlorinated insecticides, which are banned today, the currently approved pesticides are, after appropriate application, gradually degraded or detoxified by plant or microbial enzymes (in soil, water) over time under the influence of various physico-chemical factors (sunlight, rain, etc.). At the time of harvest maturity, after the expiry of the protection period, it can be assumed that the residue levels have reliably fallen below the legislatively established maximum residue limit (MLR) value. With the choice of rapidly degradable pesticides and compliance with the conditions of good agricultural practice (GAP), residues are often either undetectable or very low. On the other hand, not all principles of pesticide application are always followed; residues enter the food chain and health risks related to chronic dietary intake cannot be excluded. These concerns apply when several pesticides (cocktails) are contained in one product. In line with current trends to reduce the exposure of the environment to contaminating substances, efforts to minimize pesticide residues and promote low-residue and organic food production are also increasing. In this context, the study of residue dynamics and the search for alternative and not least effective methods of plant protection naturally play an important role.

The working group focuses on the comprehensive investigation of pesticide residues (including biocides) both from the point of view of their analytical determination and with regard to their (bio)transformation, the quality of the treated crops and the protection of consumers and the environment.

Determination of pesticide residues and their metabolites in the framework of the monitoring programmes of the SZPI and the EU. GC-MS/MS and LC-MS/MS methods accredited according to ISO17025 are used. Multi-residue methods (MRM) and specific methods for individual pesticides (SRM) are used to analyse food and natural raw materials or commodities, water samples and other environmental components.
Evaluation of pesticide residue findings in relation to EU legislation, estimation of exposure risks according to EFSA strategy and suggestions for HACCP optimisation. Evaluation of chemical protection on the quality of treated crops.
Establishment of methods for newly authorised pesticides / their metabolites and monitoring of active components of biopreparations with pesticide activity, evaluation of residue dynamics in field trials.
Control, monitoring and evaluation of the quality of BIO products, comparison with conventional products and authentication based on evidence of illegal use of pesticides.
Investigate the transfer of pesticide residues into the final product or biowaste, assess the impact of different technological processes on residues in the final product and propose remedial measures.

Publications

Drábová L.,Mráz P., Krátký F., Uttl L., Vacková P., Schusterova D., Zadražilová B., Kadlec V., Kocourek V., Hajšlová J.: Assessment of pesticide residues in citrus fruit on the Czech market. Food Additives and Contaminants: Part A (2021) 39(2): 311-319. (doi: 10.1080/19440049.2021.2001579)
Schusterova D., Hajslova J., Kocourek V., Pulkrabova J.: Pesticide residues and their metabolites in grapes and wines from conventional and organic farming system. Foods (2021) 10(2): 307. (doi: 10.3390/foods10020307)
Horska T., Kocourek F., Stara J., Holy K., Mraz P., Kratky F., Kocourek V., Hajslova J.: Evaluation of pesticide residue dynamics in lettuce, onion, leek, carrot and parsley. Foods (2020) 9 (5), 680. (doi: 10.3390/foods9050680)
Drabova L., Alvarez-Rivera G., Suchanova M., Schusterova D., Pulkrabova J., Tomaniova M., Kocourek V., Chevallier O., Elliot Ch., Hajslova J.: Food fraud in oregano: pesticide residues as adulteration markers. Food Chemistry (2019) 276:726-734. (doi:10.1016/j.foodchem.2018.09.143)
Schusterova D., Suchanova M., Pulkrabova J., Kocourek V., Urban J., Hajslova J.: Can occurrence of pesticide metabolites detected in crops provide the evidence on illegal practices in organic farming? Journal of Agricultural and Food Chemistry (2019) 67(22): 6102-6115. (doi:10.1021/acs.jafc.8b06999 )

Projects

Ministry of Agriculture

QK21020238: Inovace integrované produkce zeleniny při změně spektra prostředků ochrany, zdokonaleném monitoringu škodlivých organismů a omezení rizik pesticidů v produktech (2021 - 2023)
SS01020234: Snižování zátěže potravního řetězce a životního prostředí rezidui přípravků na ochranu rostlin při produkci ovoce (2020 - 2023)

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Metabolomics of biological systems

Metabolomics is a relatively new field of science that deals with the analysis of the metabolome, the collection of all low molecular weight substances (usually less than 1,500 Da) in and outside living organisms. This analysis is challenging due to the high temporal dynamics of the metabolome and the highly variable concentrations of metabolites. However, knowledge of the metabolome and its changes in the context of different phenomena (pathological states of the organism, altered diet, different plant species) can often provide crucial insights into understanding these phenomena.

◳ metabolomika (jpg) → (originál)

Our group analyses the metabolome of mainly biological samples (body fluids, tissues) and plants and describes changes in the metabolome in connection with many phenomena. For metabolome analysis, we use various mass spectrometric techniques, often in combination with chromatographic methods, which allow us to identify individual metabolites associated with the changes studied in organisms.

Publications

Uttl L., Bechynska K., Ehlers M., Kadlece V., Navratilova K., Dzuman Z., Fauhl-Hassek C., Hajslova J.: Critical assessment of chemometric models employed for varietal authentication of wine based on UHPLC-HRMS data. Food Control (2023) 143: 109336. (doi: 10.1016/j.foodcont.2022.109336)
Fiserova I., Trinh M.D., Elkalaf M., Vacek L., Heide M., Martinkova S., Bechynska K., Kosek V., Hajslova J., Fiser O., Tousek P., Polak J.: Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes: In vitro model of takotsubo syndrome. Frontiers in Cardiovascular Medicine (2022) 9:917989. (doi: 10.3389/fcvm.2022.917989)
Garcia C.J., Kosek V., Beltran D., Tomas-Barberan F.A., Hajslova J.: Production of New Microbially Conjugated Bile Acids by Human Gut Microbiota. Biomolecules (2022) 12(5): 687. (doi: 10.3390/biom12050687)
Kosek V., Hajsl M., Bechynska K., Kucerka O., Suttnar J., Hlavackova A., Hajslova J., Maly M.: Long-Term Effects on the Lipidome of Acute Coronary Syndrome Patients. Metabolites (2022) 12(2): 124. (doi: 10.3390/metabo12020124)
Smid V., Dvorak K., Sedivy P., Kosek V., Lenicek M., Dezortova M., Hajslova J., Hajek M., Vitek L., Bechynska K., Bruha R.: Effect of Omega-3 Polyunsaturated Fatty Acids on Lipid Metabolism in Patients With Metabolic Syndrome and NAFLD. Hepatology Communications (2022) 6(6): 1336-1349. (doi: 10.1002/hep4.1906)
Vacek L., Dvorak A., Bechynska K., Kosek V., Elkalaf M., Trinh M.D., Fiserova I., Pospisilova K., Slovakova L., Vitek L., Hajslova J., Polak J.: Hypoxia Induces Saturated Fatty Acids Accumulation and Reduces Unsaturated Fatty Acids Independently of Reverse Tricarboxylic Acid Cycle in L6 Myotubes. Frontiers in Endocrinology (2022). 13: 663625. (doi: 10.3389/fendo.2022.663625)
Bechynska K., Kosek V., Fenclova M., Muchova L., Smid V., Suk J., Chalupsky K., Sticova E., Hurkova K., Hajslova J., Vitek L., Stranska M.: The Effect of Mycotoxins and Silymarin on Liver Lipidome of Mice with Non-Alcoholic Fatty Liver Disease. Biomolecules (2021) 11: 1723. (doi: 10.3390/biom11111723)
Bechynska K., Kosek V., Zlechovcova M., Peukertova P., Hajlsova J.: Cannabis Metabolomic Data Processing: Challenges to be Addressed. LCGC (2021) Special Issues 34(s10): 11-15. (on-line)
Birse N., Chevallier O., Hrbek V., Kosek V., Hajslova J., Elliot Ch.: Ambient mass spectrometry as a tool to determine poultry production system history: A comparison of rapid evaporative ionisation mass spectrometry (REIMS) and direct analysis in real time (DART) ambient mass spectrometry platforms. Food Control (2021). 123: 107740 (doi: 10.1016/j.foodcont.2020.107740)
Maly M., Hajsl M., Bechynska K., Kucerka O., Sramek M., Suttnar J., Hlavackova A., Hajslova J., Kosek V.: Lipidomic analysis to assess oxidative stress in acute coronary syndrome and acute stroke patients. Metabolites (2021) 11(7): 412. (doi: 10.3390/metabo11070412)
Bechynska K., Daskova N., Vrzackova N., Harant K., Heczkova M., Podzimkova K., Bratova M., Dankova H., Berkova Z., Kosek V., Zelenka J., Hajslova J., Sedlacek R., Suttnar J., Hlavackova A., Bartonova L., Cahova M.: The effect of omega-3 polyunsaturated fatty acids on the liver lipidome, proteome and bile acid profile: parenteral versus enteral administration. Scientific Reports (2020) 9: 19097. (doi: 10.1038/s41598-019-54225-8)
Kosek V., Heczkova M., Novak F., Meisnerova E., Novakova O., Zelenka J., Bechynska K., Vrzacova N., Suttnar J., Hlavackova A., Dankova H., Bratova M., Daskova N., Malinska H., Oliyarnyk O., Wohl P., Bastova H., Cahova M.: The ω-3 polyunsaturated fatty acids and oxidative stress in long-term parenteral nutrition dependent adult patients: Functional lipidomics approach. Nutrients (2020) 12(8) 2351. (doi: 10.3390/nu12082351)

Projecsts

AZV

NU22-04-00389: Vliv metabolomu aterosklerotického plátu v karotidě na jeho embolizační potenciál (2022 - 2025)
NU21-01-00259: Nové inhibitory lipolýzy v léčbě poruch metabolismu lipidů a glukózy při syndromu obstrukční spánkové apnoe (2021 – 2024)
NV18-08-00149: Kritické zhodnocení lipidomu u pacientů s akutním koronárním syndromem a cévní mozkovou příhodou ve vztahu ke stupni oxidačního stresu (2018 – 2021)

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Process contaminants

Heat treatment of food serves to ensure microbial safety, longer sustainability, increase digestibility, but also to improve sensory properties such as taste, smell or color of food. The formation of these sensory active compounds is accompanied by many chemical reactions, the most important of which is the Maillard reaction. In addition to the desirable properties, so-called processing contaminants also occur, which may be probable or potential human carcinogens. The aim in such a case is to find ways to minimize the formation of these compounds in food without affecting their nutritional and sensory value.

Our research group investigates the influence of alternative mild processing technologies (e.g. vacuum frying, pulsed electric field, ohmic heating, heat sterilization under high pressure) on the formation of processing contaminants (acrylamide, furans, esters of 2- and 3-monochloropropanediol and glycidol) and on the content of biologically active compounds.

Publications

Belkova B., Chytilova L., Kocourek V., Slukova M., Mastovska K., Kyselka J., Hajslova J.: Influence of dough composition on the formation of processing contaminants in yeast-leavened wheat toasted bread. Food Chemistry (2021) 338: 127715 (doi: 10.1016/j.foodchem.2020.127715)
Gaca A., Kludska E., Hradecky J., Hajslova J., Jelen H.H.: Changes in volatile compound profiles in cold-pressed oils obtained from various seeds during accelerated storage. Molecules (2021) 23(2): 285. (doi: 10.3390/molecules26020285)
Gratz M., Sevenich R., Hoppe T., Schottroff F., Vlaskovic N., Belkova B., Chytilova L, Filatova M., Stupak M., Hajslova J., Rauh C., Jaeger H.: Gentle Sterilization of Carrot-Based Purees by High-Pressure Thermal Sterilization and Ohmic Heating and Influence on Food Processing Contaminants and Quality Attributes. Frontiers in Nutrition (2021). 8: 643837. (doi: 10.3389/fnut.2021.643837)
Robert Sevenich, Cornelia Rauh, Beverly Belkova, Jana Hajslova, Chapter 6 - Effect of high-pressure thermal sterilization (HPTS) on the reduction of food processing contaminants (e.g., furan, acrylamide, 3-MCPD-esters, HMF), Editor(s): Francisco J. Barba, Carole Tonello-Samson, Eduardo Puértolas, María Lavilla, Present and Future of High Pressure Processing, Elsevier, 2020, Pages 139-172, ISBN 9780128164051. https://doi.org/10.1016/B978-0-12-816405-1.00006-6.

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Organic pollutants in food, environment and human biomonitoring studies

Industrial contaminants in the food chain

Human population uses a number of chemicals on a daily basis that can be released into the environment, where they can have negative effects and persist for a long time. These compounds can be found in various environmental compartments, including water, air, or soil, which together with sediments can represent a significant reservoir of persistent substances. Undesirable substances penetrate into environment by various ways, including atmospheric deposition, the use of contaminated water for irrigation or through accidental spills.

Our research group has been involved in the analysis of environmental contaminants for a long time. From the group of persistent organic pollutants (POPs), we focus on brominated flame retardants. (BFR), polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), chlorinated paraffins (CPs), perfluoroalkylated substances (PFAS), but also polycyclic aromatic hydrocarbons (PAHs), phthalates, UV filters, organophosphate flame retardants (OPFRs). In many studies, we monitor these chemicals not only in food and food supplements, but also in environmental compartments such as air, dust, sediments, soil, water, etc. Recently, we have been analyzing these compounds in food contact materials and other object of everyday use as they represent significant sources of human exposure to these chemicals. Within the research projects, we develop the required multianalytical methods, in which gas or liquid chromatography coupled with mass spectrometry is used as an instrumental technique.

Publications

Drabova L., Dvorakova D., Urbancova K., Gramblicka T., Hajslova J., Pulkrabova J.: Critical Assessment of Clean-Up Techniques Employed in Simultaneous Analysis of Persistent Organic Pollutants and Polycyclic Aromatic Hydrocarbons in Fatty Samples. Toxics (2022), 10 (1),12. (doi: 10.3390/toxics10010012)
Jurikova M., Dvorakova D., Pulkrabova J.: The occurrence of perfluoroalkyl substances (PFAS) in drinking water in the Czech Republic: a pilot study. Environmental Science and Pollution Research (2022) published (doi: 10.1007/s11356-022-20156-7)
Tomasko J., Hrbek V., Kourimsky T., Stupak M., Hajslova J., Pulkrabova J.: Are fish oil-based dietary supplements a significant source of exposure to chlorinated paraffins? Science of the Total Environment (2022) 833, 155137. (doi: 10.1016/j.scitotenv.2022.155137)
Tomasko J., Stupak M., Hajslova J., Pulkrabova J.: Application of the GC-HRMS based method for monitoring of short- and medium-chain chlorinated paraffins in vegetable oils and fish. Food Chemistry (2021) in press. (doi: 10.1016/j.foodchem.2021.129640)
Polachova A., Gramblicka T., Parizek O., Sram R.J., Stupak M., Hajslova J., Pulkrabova J.: Estimation of human exposure to polycyclic aromatic hydrocarbons (PAHs) based on the dietary and outdoor atmospheric monitoring in the Czech Republic. Environmental Research (2020) 182: 108977. (doi: 10.1016/j.envres.2019.108977)

Projects

GAČR - Vliv nových chlorovaných kontaminantů na adipogenezi, 21-19437S, 01/2021 – 12/2023
Horizon 2020 - PAPILLONS - Plastic in Agricultural Production: Impacts, Lifecycles and Long-term Sustainability, 101000210, 6/2021 - 5/2025
EFSA - Screening for emerging chemical risks in the food chain, OC/EFSA/SCER/2020/02, 02/2021 – 01/2024

Biomonitoring, exposom

Today, humans are exposed to mixtures of chemicals that are released into the environment from various commercial and industrial applications. Some of them can have an adverse effect on human health. Therefore, it is necessary to monitor the quality of the environment and to assess its impact on humans. For this purpose, human biological monitoring (biomonitoring) is applied and provides, which provides data on the amount of chemicals and their metabolites in the body by analyzing suitable biological samples, such as blood serum / plasma, urine, breast milk, etc.

◳ HBM obrázek web - návrh_finAJ (png) → (šířka 215px)

„Human Biological Monitoring“, Zielhuis, 1984

“a systematic continuous or repetitive activity for collection of biological samples for analysis of concentrations of pollutants, metabolites or specific non-adverse biological effect parameters for immediate application, with the objective to assess exposure and health risk to exposed subjects, comparing the data observed with the reference level and — if necessary — leading to corrective actions”

Our research group has been involved in European biomonitoring for many years. We develop multianalytical procedures based on chromatography and mass spectrometry, which meet the requirements of ultratrace analysis for the determination of different groups of environmental contaminants in one analysis. The group of persistent organohalogenated pollutants are represented by brominated flame retardants, polychlorinated biphenyls, chlorinated pesticides, chlorinated paraffins, perfluoroalkylated compounds, but also polycyclic aromatic hydrocarbons, phthalates, UV filters, organophosphate flame retardants, including their metabolites.

Publications

Nübler S., Lopez M. E., Castano A., Mol H. G. J., Haji-Abbas-Zarrabi K., Schäfer M., Hajslova J., Dvorakova D., Antignac J.-P., Koch H. M., Huag L. S., Vorkamp K., Göen T.: Interlaboratory Comparison Investigations (ICIs) and External Quality Assurance Schemes (EQUASs) for human biomonitoring of perfluoroalkyl substances (PFASs) in serum as part of the quality assurance programme under HBM4EU. Science of The Total Environment (2022) 847: 157481 (doi: 10.1016/j.scitotenv.2022.157481)
Ambroz A., Rossner Pavel Jr., Rossnerova A., Honkova K., Milcova A., Pastorkova A., Klema J., Pulkrabova J., Parizek O., Vondraskova V., Zelenka J., Vrzackova N., Schmuczerova J., Topinka J., Sram R.J.: Oxidative Stress and Antioxidant Response in Populations of the Czech Republic Exposed to Various Levels of Environmental Pollutants. Environmental Research and Public Health (2022). 19, 3609. (doi: 10.3390/ijerph19063609)
Cerna M., Grafnetterova A.P., Dvorakova D., Pulkrabova J., Maly M., Janos T., Vodrazkova N., Tupa Z., Puklova V.: Biomonitoring of PFOA, PFOS and PNFNA in human milk from Czech Republic, time trends and estimation of infant’s daily intake.Environmental Research (2020) in press. (doi: 1016/j.envres.2020.109763)
Dvorakova D., Pulkrabova J., Gramblicka T., Polachova A., Buresova M., Hajslova J., López M.E., Castaño A., Nübler S., Haji-Abbas-Zarrabi K., Klausner N., Göen T., Mol H., Koch H.M., Vaccher V., Antignac J.-P., Haug L.S., Vorkamp K.: Interlaboratory Comparison Investigations (ICIs) and External Quality Assurance Schemes (EQUASs) for Flame Retardant Analysis in Biological Matrices: Results from the HBM4EU Project. Environmental Research (2021) 202: 111705. (doi: 10.1016/j.envres.2021.111705)
Polachova A., Gramblicka T., Bechynska K., Parizek O., Turnerova, Dvorakov, Honkova K., Rossnerova A., Rossner P., Sram R.J., Topinka J., Pulkrabova J.: Biomonitoring of 89 POPs in blood serum samples of Czech city policemen. Environmental Pollution (2021) 291: 118140(doi: 10.1016/j.envpol.2021.118140)
Urbancova K., Sram R.J., Hajslova J., Pulkrabova J.: Concentrations of Phthalate and DINCH Metabolites in Urine Samples from Czech Mothers and Newborns. Exposure and Health (2021) 14: 17-27 (doi: 10.1007/s12403-021-00415-7)

Projects

GAČR - Vliv nových chlorovaných kontaminantů na adipogenezi, 21-19437S, 01/2021 – 12/2023

Horizon Europe - PARC - European Partnership for the Assessment of Risks from Chemicals, HORIZON-HLTH-2021-ENVHLTH-03, No. 101057014, 5/2022 - 4/2029

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Nutritionally significant food components and food additives

Biologically active compounds, nutritional assessment of food quality

Biologically active compounds can have positive as well as negative biological effects. Their content depends on the type of plant or growing conditions, but is also affected by the conditions of storage and technological processing. Modern analytical methods are used to monitor the levels of biologically active compounds and to assess their stability, based primarily on liquid chromatography techniques in conjunction with conventional detection and mass spectrometry.

The working group is dedicated to the determination of levels of carotenoids, tocopherols, chlorophylls, cyanogenic glycosides, polyphenols, flavonoids, phytoestrogens, galactolitips, glycoalkaloids and many other groups of substances in foods and food raw materials, feeds, microalgae or food supplements. Attention is paid to the determination of hydrophilic (B1, B2, B6, B9, C) but also lipophilic (A, E, D) vitamins, basic food components and raw materials such as carbohydrates (sugars, polyalcohols, starches, inulin polysaccharide), proteins, amino acids, fats (fatty acids) and others. The aim is a comprehensive assessment of food quality, including the determination of nutritional value. The stability of the monitored substances is studied.

As a member of the Czech Technological Platform for Organic Agriculture, we study the quality of organic farming products and organic food.

Publications:

Jiru M., Stranska-Zachariasova M., Kohoutkova J., Schulzova V., Krmela A., Revenco D., Koplik R., Kastanek P., Fulin T., Hajslova J.: Potential of microalgae as source of health-beneficial bioactive components in produced eggs. Journal of Food Science and Technology (2021) (doi: 10.1007/s13197-020-04896-3)
Koudela M., Schulzova V., Krmela A., Chmelarova H., Hajslova J., Novotny C.: Effect of Agroecological Conditions on Biologically Active Compounds and Metabolome in Carrot. Cells (2021) 104, 784. (doi: 10.3390/cells10040784)
Bhave A., Schulzova V., Mrnka L., Hajslova J.: Influence of harvest date and post-harvest treatment on carotenoids and flavonoids composition in French marigold flowers. Journal of Agricultural and Food Chemistry (2020) 68 (30): 7880-7889. (doi: 10.1021/acs.jafc.0c02042)
Novotny C., Schulzova V., Krmela A., Hajslova J., Svobodova K., Koudela M.: Ascorbic Acid and Glucosinolate Levels in New Czech Cabbage Cultivars: Effect of Production System and Fungal Infection. Molecules (2018) 23(8): 1855. (doi: 10.3390/molecules23081855)
Bhave A., Schulzova V., Chmelarova H., Mrnka L., Hajslova J.: Assessment of the rosehips based on their biologically active compound content. Journal of Food and Drug Analysis (2017) 25 (3): 681-690. (doi: 10.1016/j.jfda.2016.12.019 )
Pavelkova P., Krmela A., Schulzova V.: Determination of carotenoids in flowers and food supplements by HPLC-DAD. Acta Chimica Slovaca (2020) 13 (‏ 1): 6-12
Rollova M., Gharwalova L., Krmela A., Schulzova V., Hajslova J., Jaros P., Kolouchova I., Matatkova O.: Grapevine extracts and their effect on selected gut-associated microbiota: In vitro study. Czech Journal of Food Sciences (2020) 38 (3):‏. 137-143 doi: 10.17221/308/2019-CJFS
Humhal T., Kronusová O., Kaštánek P., Potočár T., Kohoutková J., Brányik T.: Influence of nitrogen sources on growth of thraustochytrids in waste water from the demineralization of cheese whey. Czech Journal of Food Sciences (2019) 37(5): 383-390. (doi: 10.17221/172/2018-CJFS)

Certified methodologies:

Hajšlová J., Kohoutková J., Zachariášová M.: Method for determining the content of polyunsaturated fatty acids in micro-algae as part of feed for poultry and other animals. (2015) Certified methodology. VŠCHT, ISBN 978-80-7080-925-9
Hajšlová J., Krmela A., Schulzová V.: Determination of inulin polysaccharide. Certified methodology (2015) VŠCHT, Praha. ISBN 978-80-7080-926-6
Hajšlová J., Schulzová V., Krtková V., Nedělník J.: Determination of phytoestrogens in plant matrices. Certified methodology No. 2014/96506, (2014). ISBN 978-80-7080-874-0
Hajšlová J., Schulzová V., Křížová L., Pavlok S.: Determination of phytoestrogens in biological material and dairy products. Certified methodology No. 2011/12-1 (2011) ISBN 978-80-7080-805-4

Additives

◳ aditiva Schulzova (png) → (šířka 215px)

Additives, whether of natural or synthetic origin, are intentionally added to foods for technological purposes such as improving or maintaining their durability, appearance, consistency, taste or smell. It is a diverse group of substances, especially from the categories of organic and inorganic dyes, sweeteners, aroma intensifiers, preservatives, antioxidants, emulsifiers, etc., differing in chemical structure and properties and their use is legally controlled. The research topic of the group includes the development and implementation of modern analytical strategies, providing new possibilities in the control of food safety and authenticity. Attention is focused on the development of multidetection methods, using mainly the technique of liquid chromatography in conjunction with high-resolution mass spectrometry to control the levels of additives, defined by Regulation (EC) No. 1333/2008 from the group of sweeteners, preservatives and synthetic colors in food. The working group also offers significant use in proving the addition of unauthorized synthetic substances, especially dyes, to food.

Publications:

Krmela A., Kharoshka A., Schulzova V., Pulkrabova J., Hajslova J.: A Simple LC–MS Multi-analyte Method to Determine Food Additives and Caffeine in Beverages. LCGC Europe (2020) 33(7): 327-335

Certified methodologies:

Krmela A., Kharoshka A., Schulzová V., Stránská M., Hajšlová J.: Method for determination of sweeteners and preservatives in beverages and foodstuffs. (2020) Certified methodology. VŠCHT, ISBN: 978-80-7592-080-5

Projects:

TAČR - Development of innovative analytical strategies usable for control of safety and authenticity of food and food raw materials TJ02000238, 2019 - 2020

International projects - ongoing

Název	Poskytovatel	Kód	Období
PARC - European Partnership for the Assessment of Risks from Chemicals	EK, Horizon Europe	No. 101057014	2022 - 2029
PAPILLONS - Plastic in Agricultural Production: Impacts, Lifecycles and Long-term Sustainability About project PAPILLONS will elucidate ecological and socioeconomic sustainability of agricultural plastics (APs) in relation to releases and impacts of micro- and nanoplastics (MNPs) in European soils. We will advance knowledge on sources, behaviour and impacts through cross-disciplinary research, bringing together scientists from chemistry, materials engineering, agronomy, soil ecology, toxicology and social sciences. We will transform the scientific knowledge generated into guidance on specific solutions by applying a Multi-actor approach, involving actors in the agricultural and policy sector and world-leading industries. This will enable co-creation of knowledge and provide the scientific background to enable policy, agricultural and industrial innovation towards sustainable farm production systems. We will deliver the first digital European atlas of AP use, management and waste production to estimate sources of MNP to agricultural soils. We will run integrative studies at laboratory, mesocosm and field scales in different parts of Europe to address: occurrence of AP-derived MNPs; MNP behaviour and transport in soil; uptake by biota and crops; long-term impacts on soil properties, fertility and ecological services; effects on biological and functional diversity across multiple scales; effects on plant production and quality; and socioeconomic impacts of AP-based practices. We will focus on multigenerational effect studies for relevant traditional and biodegradable polymers, at realistic and future high-exposure scenarios. PAPILLONS partners pioneered soil MNP research, host the majority of European analytical capacity for assessing soil contamination and will provide validated, high-throughput analysis for MNPs in soil. Using innovative applications of state-of the- art analytical chemistry, we will advance analysis down to the nanoscale range and develop novel radiolabelled nanoplastics for accurately tracking behaviour and transport in soil and uptake by biota and crops.	EK, H2020	No. 101000210	2021 - 2025
Screening for emerging chemical risks in the food chain	EFSA	OC/EFSA/SCER/2020/02	2021 - 2023
FOODSAFETY4EU - MULTI-STAKEHOLDER PLATFORM FOR FOOD SAFETY IN EUROPE	EK, H2020	H2020-FNR-2020-1 No. 101000613	2021 - 2023

International projects - finished

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International projects - finished

Coordinator UCT Prague: Prof. Jana Hajslova, Ph.D.

Finished projects

Title	Funded by	Code	Period
METROFOOD-PP - METROFOOD-RI Preparatory Phase Project	EK, H2020	H2020-INFRADEV-2019-2 No. 871083	2020 - 2022
EU-China-Safe - Delivering an Effective, Resilient and Sustainable EU-China Food Safety Partnership	EK, H2020	H2020-SFS-2016-2 No. 727864	2017 - 2022
HBM4EU - European Human Biomonitoring Initiative	EK, H2020	SC1-PM-05-2016, H2020-SC1-2016-RTD No. 733032	2017 - 2022
FoodSmartphone - Smartphone analyzers for on-site testing of food quality and safety	EK, H2020	H2020-MSCA-ITN-2016 No. 720325	2017 - 2021
NORFRYG - Increased assortment, quality and value of Norwegian frozen vegetables	The Research Council of Norway/Foundation for Research Levy on Agricultural Products (FFL)	256388/E50	2016 - 2019
MultiCoop - Multidisciplinary approach to strengthen cooperation and establish novel platform for comprehensive assessment of food and feed safety	EK, H2020	H2020-TWINN-2015-Twinning 692195	2016 - 2018
FOODINTEGRITY - Ensuring the Integrity of the European food chain	EK, FP7	CL, 613688, FP7-KBBE-2013-7-single-stage	2014 – 2018
AUTHENT-NET - Food Authenticity Research Network	EK, H2020	H2020-SFS-2015-1-696371	2016 - 2018
Establishing of Institutional Cooperation between UiT The Arctic University of Norway and University of Chemistry and Technology in Prague in education in the field of food quality and biotechnology www.uct-uit-cooperation.eu	EEA and Norway grants, CZ07 - Bilateral Scholarship Programme	NF-CZ07-ICP-3-2642015	2015 - 2016
Occurrence of tropane alkaloids in food	EFSA	BIOCONTAM_2014_GA1	2015 - 2016
AuthenticFood - Fast methods for AUTHENTICation of organic plant based FOODs	EK, FP7	ERA–NET–CORE ORGANIC II	2010 - 2013
FOODSEG - Safe Food for Europe – Coordination of research activities and Dissemination of research results of EC funded research on food safety	EK, FP7	FP7–266061–CSA	2011 - 2014
NANOLYSE - Nanoparticles in food: Analytical methods for detection and characterisation	EK, FP7	FP7–245162–CP	2011 - 2013
PROMETHEUS - PROcess contaminants: Mitigation and Elimination Techniques for High food quality and their Evaluation Using Sensors & Simulation	EK, FP7	FP7–265558–CP	2011 - 2014
QSAFFE - Quality and SAfety of Feeds and Food for Europe	EK, FP7	FP7–265702–CP	2011 - 2014
SUCCIPACK - Development of active, intelligent and sustainable food PACKaging using PolybutyleneSUCCInate	EK, FP7	FP7–289196–CP	2012 - 2014
PERFOOD – PERFluorinated Organics in Our Diet	EK, FP7	FP7-KBBE-2008-2B	2009 – 2012
CONFFIDENCE – Contaminants in Food and Feed, Inexpensive detection for control of exposure	EK, FP7	KBBE-2007-2-4-02	2009 – 2012
EMERCON – Identification and quantification of emerging organic contaminants in the Czech aquatic ecosystem and food market supply. With focus on perfluorinated alkylated compounds	EEA Grants / NVF	A/CZ0046/2/0026	2009 – 2010
TRUEFOOD – Traditional United Europe Food	EK, FP6	FOOD CZ-2006-016264	2006 – 2010
TRACE – Tracing the origin of food	EK, FP6	FOOD-006942	2003 – 2009
QUALITY LOW INPUT FOOD – Improving quality and safety and reduction of cost in the European organic and "low input" supply chains	EK, FP6	FOOD-CT-2003-506358	2003 – 2009
HEATOX – Heat-generated food toxicants – Identification, characterisation and risk minimisation	EK, FP6	Food-CT-2003-506820	2003 – 2010
BIOCOP – New Technologies to Screen Multiple Contaminants in Foods	EK, FP6	FOOD-CT-2004-06988	2004 – 2010
STAMPS – Standardized passive samplers. Sampling and determination of priority pollutants in surface waters bioavailable fraction.	EK, FP5	EVK1-CT-2002-00119	2003 – 2006
FIRE – Brominated flame retardants – integrated risk assessment for endocrine effects. Assessment of contamination levels, analytical techniques	EK, FP5	QLK4-CT-2002-00596	2003 – 2007
The presence and risk of nitro-polycyclic aromatic hydrocarbons. INCO – COPERNICUS	EK, FP4	IC15 CT98 0339	1999 – 2002
IENICA-MILLENIUM: Interactive European Network For Industrial Crops And Their Applications	EK, FP4	QLRT-2000-0011	2000 – 2003
Disseminating the results of EU food research programmes to small and medium sized food industries, health professionals and consumer groups a 24 – country interactive network. Flair Flow 4	EK, FP4	QLK1-CT-2000-00040	2000 – 2003
Biological reference materials for organic contaminants – BROC	EK	EU-SMT BROC01/05	2002 – 2004
Minimization of pesticide residues in processed products and the environment. Pesticides in baby food Analytical methods and the effect of processing on pesticide residues – minimization of residues, HACCP.	NATO SfP	SfP-977983	1999 – 2005

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Bachelor Study Programme

Chemistry and Technology, specialization Food Chemistry and Technology

Master Study Programmes

Biotechnology and Food Science

Doctoral Study Programme

Food and Natural Products

A. FOOD/FEED CHEMICAL SAFETY, HUMAN EXPOSURE, AND FORENSIC ISSUES

B. FOOD QUALITY ATTRIBUTES AND AUTHENTICATION; BIOPROSPECTION

DATA

A. FOOD/FEED CHEMICAL SAFETY, HUMAN EXPOSURE, AND FORENSIC ISSUES

B. FOOD QUALITY ATTRIBUTES AND AUTHENTICATION; BIOPROSPECTION

GC-MS/MS Agilent 7000B Triple Quadrupole

GC-MS/MS Agilent 7000B Triple Quadrupole

GC-MS/MS Agilent 7000C Triple Quadrupole

GC-MS/MS Agilent 7010 Triple Quadrupole

GC-HRMS Pegasus HRT (LECO)

GC-MS Agilent 5973 Single Quadrupole

GCxGC-MS Pegasus® 4D

GC-HRMS Agilent 7200b

The instrumentation is utilized at the Department of Analytical Chemistry and in the field of metabolomic analysis, ultra-trace analysis, and it is also used for the identification of unknown compounds.

Liquid chromatograph Vanquish Horizon hyphenated to mass spectrometer Exploris 240

U-HPLC‒MS/MS (Acquity UPLC – QTRAP 5500)

U-HPLC‒MS/MS (Agilent 1290 Infinity II – QTRAP 6500+)

U-HPLC‒HRMS (Acquity UPLC – Exactive)

U-HPLC‒HRMS/MS (UltiMate 3000 – Q-Exactive Plus)

Acquity UPLC liquid chromatograph coupled with with Xevo TQ-S mass spectrometer (LC-MS/MS)

Acquity UPLC liquid chromatograph coupled with Synapt G2 high resolution mass spectrometer (LC-HRMS)

Aquity UPC2 supercritical fluid chromatograph coupled with Synapt G2 Si high-resolution mass spectrometer (SFC-HRMS)

Acquity UPLC liquid chromatograph coupled with Quattro Premier XE mass spectrometer (LC-MS/MS)

Acquity UPLC liquid chromatograph coupled with QDa mass spectrometer (LC-MS)

Dionex UltiMate 3000 U-HPLC liquid chromatograph coupled with TripleTOFTM 6600 high resolution tandem mass spectrometric detector (LC-HRMS)

Agilent 6560 Ion Mobility Q-TOF LC/MS (Agilent Technologies)

AutoPure prep LC – LCT Premier XE (Waters)

Agilent 6495 Triple Quadrupole LC/MS (Agilent Technologies)

Agilent 6495C Triple Quadrupole LC/MS (Agilent Technologies)

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Bioactive secondary metabolites of plants and microorganisms

Natural toxic compounds, mycotoxins, alkaloids

Cannabinoids

Food Chemistry and Elemental Analysis

The Maillard reaction and other non-enzymatic browning reactions in foods

Minerals and trace elements in food

Elemental speciation analysis

Analysis of inorganic nanoparticles

Other areas of interest

Pesticide/biocide residues in food and the environment

Metabolomics of biological systems

Process contaminants

Organic pollutants in food, environment and human biomonitoring studies

Industrial contaminants in the food chain

Biomonitoring, exposom

Nutritionally significant food components and food additives

Biologically active compounds, nutritional assessment of food quality

Additives

International projects - ongoing

International projects - finished

International projects - finished

Finished projects